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Results: 1 to 20 of 105

Similar articles for PubMed (Select 25079318)

1.

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.

Anders C, Niewoehner O, Duerst A, Jinek M.

Nature. 2014 Sep 25;513(7519):569-73. doi: 10.1038/nature13579. Epub 2014 Jul 27.

2.

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

Sternberg SH, Redding S, Jinek M, Greene EC, Doudna JA.

Nature. 2014 Mar 6;507(7490):62-7. doi: 10.1038/nature13011. Epub 2014 Jan 29.

3.

Crystal structure of Cas9 in complex with guide RNA and target DNA.

Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O.

Cell. 2014 Feb 27;156(5):935-49. doi: 10.1016/j.cell.2014.02.001. Epub 2014 Feb 13.

4.

Programmable RNA recognition and cleavage by CRISPR/Cas9.

O'Connell MR, Oakes BL, Sternberg SH, East-Seletsky A, Kaplan M, Doudna JA.

Nature. 2014 Dec 11;516(7530):263-6. doi: 10.1038/nature13769. Epub 2014 Sep 28.

PMID:
25274302
5.

Cas9 specifies functional viral targets during CRISPR-Cas adaptation.

Heler R, Samai P, Modell JW, Weiner C, Goldberg GW, Bikard D, Marraffini LA.

Nature. 2015 Mar 12;519(7542):199-202. doi: 10.1038/nature14245. Epub 2015 Feb 18.

PMID:
25707807
6.

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems.

Fonfara I, Le Rhun A, Chylinski K, Makarova KS, LĂ©crivain AL, Bzdrenga J, Koonin EV, Charpentier E.

Nucleic Acids Res. 2014 Feb;42(4):2577-90. doi: 10.1093/nar/gkt1074. Epub 2013 Nov 22.

7.

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

Cho SW, Kim S, Kim Y, Kweon J, Kim HS, Bae S, Kim JS.

Genome Res. 2014 Jan;24(1):132-41. doi: 10.1101/gr.162339.113. Epub 2013 Nov 19.

8.

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.

Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR.

Nat Biotechnol. 2013 Sep;31(9):839-43. doi: 10.1038/nbt.2673. Epub 2013 Aug 11.

9.

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.

Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK.

Nat Biotechnol. 2014 Mar;32(3):279-84. doi: 10.1038/nbt.2808. Epub 2014 Jan 26.

10.

CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences.

Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G.

Nucleic Acids Res. 2014 Jun;42(11):7473-85. doi: 10.1093/nar/gku402. Epub 2014 May 16.

11.

Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA.

Science. 2014 Mar 14;343(6176):1247997. doi: 10.1126/science.1247997. Epub 2014 Feb 6.

12.

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus.

Karvelis T, Gasiunas G, Miksys A, Barrangou R, Horvath P, Siksnys V.

RNA Biol. 2013 May;10(5):841-51. doi: 10.4161/rna.24203. Epub 2013 Mar 27.

13.

Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.

Szczelkun MD, Tikhomirova MS, Sinkunas T, Gasiunas G, Karvelis T, Pschera P, Siksnys V, Seidel R.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9798-803. doi: 10.1073/pnas.1402597111. Epub 2014 May 27.

15.

CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference.

Hochstrasser ML, Taylor DW, Bhat P, Guegler CK, Sternberg SH, Nogales E, Doudna JA.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6618-23. doi: 10.1073/pnas.1405079111. Epub 2014 Apr 18.

16.

Programmable DNA cleavage in vitro by Cas9.

Karvelis T, Gasiunas G, Siksnys V.

Biochem Soc Trans. 2013 Dec;41(6):1401-6. doi: 10.1042/BST20130164. Review.

PMID:
24256227
17.

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E.

Science. 2012 Aug 17;337(6096):816-21. doi: 10.1126/science.1225829. Epub 2012 Jun 28.

18.

Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition.

Westra ER, Semenova E, Datsenko KA, Jackson RN, Wiedenheft B, Severinov K, Brouns SJ.

PLoS Genet. 2013;9(9):e1003742. doi: 10.1371/journal.pgen.1003742. Epub 2013 Sep 5.

19.

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease.

Cho SW, Kim S, Kim JM, Kim JS.

Nat Biotechnol. 2013 Mar;31(3):230-2. doi: 10.1038/nbt.2507. Epub 2013 Jan 29.

PMID:
23360966
20.

Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage.

Cencic R, Miura H, Malina A, Robert F, Ethier S, Schmeing TM, Dostie J, Pelletier J.

PLoS One. 2014 Oct 2;9(10):e109213. doi: 10.1371/journal.pone.0109213. eCollection 2014.

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