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Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading.

LeBlanc KT, Walcott ME, Gaur T, O'Connell SL, Basil K, Tadiri CP, Mason-Savas A, Silva JA, van Wijnen AJ, Stein JL, Stein GS, Ayers DC, Lian JB, Fanning PJ.

J Cell Physiol. 2014 Jul 30. doi: 10.1002/jcp.24727. [Epub ahead of print]


Surface zone articular chondrocytes modulate the bulk and surface mechanical properties of the tissue-engineered cartilage.

Peng G, McNary SM, Athanasiou KA, Reddi AH.

Tissue Eng Part A. 2014 Dec;20(23-24):3332-41. doi: 10.1089/ten.TEA.2014.0099.


Role of miR-146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro.

Jin L, Zhao J, Jing W, Yan S, Wang X, Xiao C, Ma B.

Int J Mol Med. 2014 Aug;34(2):451-63. doi: 10.3892/ijmm.2014.1808. Epub 2014 Jun 16.


Age-related alterations in TGF beta signaling as a causal factor of cartilage degeneration in osteoarthritis.

van der Kraan PM.

Biomed Mater Eng. 2014;24(1 Suppl):75-80. doi: 10.3233/BME-140976.


Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1β-stimulated production of chemokines and matrix-degrading enzymes in vitro.

Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borzì RM, Meliconi R.

PLoS One. 2014 May 12;9(5):e96925. doi: 10.1371/journal.pone.0096925. eCollection 2014.


Oxygen tension affects lubricin expression in chondrocytes.

Hatta T, Kishimoto KN, Okuno H, Itoi E.

Tissue Eng Part A. 2014 Oct;20(19-20):2720-7. doi: 10.1089/ten.TEA.2013.0353. Epub 2014 May 20.


Cartilage-specific deletion of Mig-6 results in osteoarthritis-like disorder with excessive articular chondrocyte proliferation.

Staal B, Williams BO, Beier F, Vande Woude GF, Zhang YW.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2590-5. doi: 10.1073/pnas.1400744111. Epub 2014 Feb 3.


Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis.

Akasaki Y, Hasegawa A, Saito M, Asahara H, Iwamoto Y, Lotz MK.

Osteoarthritis Cartilage. 2014 Jan;22(1):162-70. doi: 10.1016/j.joca.2013.11.004. Epub 2013 Nov 21.


Toll-like receptors in human chondrocytes and osteoarthritic cartilage.

Sillat T, Barreto G, Clarijs P, Soininen A, Ainola M, Pajarinen J, Korhonen M, Konttinen YT, Sakalyte R, Hukkanen M, Ylinen P, Nordström DC.

Acta Orthop. 2013 Dec;84(6):585-92. doi: 10.3109/17453674.2013.854666. Epub 2013 Nov 18.


Biomechanical properties and mechanobiology of the articular chondrocyte.

Chen C, Tambe DT, Deng L, Yang L.

Am J Physiol Cell Physiol. 2013 Dec 15;305(12):C1202-8. doi: 10.1152/ajpcell.00242.2013. Epub 2013 Sep 25. Review.


rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ.

Venkatesan JK, Rey-Rico A, Schmitt G, Wezel A, Madry H, Cucchiarini M.

J Transl Med. 2013 Sep 13;11:211. doi: 10.1186/1479-5876-11-211.


Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis.

Pesesse L, Sanchez C, Delcour JP, Bellahcène A, Baudouin C, Msika P, Henrotin Y.

Osteoarthritis Cartilage. 2013 Dec;21(12):1913-23. doi: 10.1016/j.joca.2013.08.018. Epub 2013 Aug 22.


Effect of preculture and loading on expression of matrix molecules, matrix metalloproteinases, and cytokines by expanded osteoarthritic chondrocytes.

Jeon JE, Schrobback K, Meinert C, Sramek V, Hutmacher DW, Klein TJ.

Arthritis Rheum. 2013 Sep;65(9):2356-67. doi: 10.1002/art.38049.


Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo.

Shepard JB, Jeong JW, Maihle NJ, O'Brien S, Dealy CN.

Arthritis Res Ther. 2013;15(3):R60.


Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage.

Fernandes AM, Herlofsen SR, Karlsen TA, Küchler AM, Fløisand Y, Brinchmann JE.

PLoS One. 2013 May 9;8(5):e62994. doi: 10.1371/journal.pone.0062994. Print 2013.


Identification of soluble 14-3-3∊ as a novel subchondral bone mediator involved in cartilage degradation in osteoarthritis.

Priam S, Bougault C, Houard X, Gosset M, Salvat C, Berenbaum F, Jacques C.

Arthritis Rheum. 2013 Jul;65(7):1831-42. doi: 10.1002/art.37951.


Dynamic compression improves biosynthesis of human zonal chondrocytes from osteoarthritis patients.

Jeon JE, Schrobback K, Hutmacher DW, Klein TJ.

Osteoarthritis Cartilage. 2012 Aug;20(8):906-15. doi: 10.1016/j.joca.2012.04.019. Epub 2012 Apr 28.


Cryopreservation effect on proliferative and chondrogenic potential of human chondrocytes isolated from superficial and deep cartilage.

Muiños-López E, Rendal-Vázquez ME, Hermida-Gómez T, Fuentes-Boquete I, Díaz-Prado S, Blanco FJ.

Open Orthop J. 2012;6:150-9. doi: 10.2174/1874325001206010150. Epub 2012 Apr 6.


Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice.

Oh H, Chun CH, Chun JS.

Arthritis Rheum. 2012 Aug;64(8):2568-78. doi: 10.1002/art.34481.


Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage.

Wei F, Zhou J, Wei X, Zhang J, Fleming BC, Terek R, Pei M, Chen Q, Liu T, Wei L.

Osteoarthritis Cartilage. 2012 Jul;20(7):755-63. doi: 10.1016/j.joca.2012.03.010. Epub 2012 Mar 30.

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