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Attenuation of IFN-γ-induced B7-H1 expression by 15-deoxy-delta(12,14)-prostaglandin J2 via downregulation of the Jak/STAT/IRF-1 signaling pathway.

Seo SK, Seo DI, Park WS, Jung WK, Lee DS, Park SG, Choi JS, Kang MS, Choi YH, Choi I, Yu BC, Choi IW.

Life Sci. 2014 Sep 1;112(1-2):82-9. doi: 10.1016/j.lfs.2014.07.021. Epub 2014 Jul 26.


Inhibition of IL-10-induced STAT3 activation by 15-deoxy-Delta12,14-prostaglandin J2.

Ji JD, Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon HJ, Sohn J, Song GG.

Rheumatology (Oxford). 2005 Aug;44(8):983-8. Epub 2005 Apr 19.


15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells.

Panzer U, Zahner G, Wienberg U, Steinmetz OM, Peters A, Turner JE, Paust HJ, Wolf G, Stahl RA, Schneider A.

Nephrol Dial Transplant. 2008 Dec;23(12):3776-85. doi: 10.1093/ndt/gfn361. Epub 2008 Jul 2.


Quantitative characterization of 15-deoxy-delta(12,14)-prostaglandin J2 in regulating EGFPSmad2 translocation in CHO cells through PPARgamma/TGFbeta/Smad2 pathway.

Ye F, Sun T, Luo H, Ding H, Chen K, Shen X, Jiang H.

Cell Physiol Biochem. 2006;18(1-3):143-50. Epub 2006 Aug 15.


15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism.

Willermain F, Dulku S, Gonzalez NS, Blero D, Driessens G, De Graef C, Caspers L, Bruyns C.

Prostaglandins Other Lipid Mediat. 2006 Sep;80(3-4):136-43. Epub 2006 Jul 14.


Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274).

Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, Oh S, Shin JG, Yao S, Chen L, Choi IH.

FEBS Lett. 2006 Feb 6;580(3):755-62. Epub 2006 Jan 9.


Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway.

Kim EJ, Park KS, Chung SY, Sheen YY, Moon DC, Song YS, Kim KS, Song S, Yun YP, Lee MK, Oh KW, Yoon DY, Hong JT.

J Pharmacol Exp Ther. 2003 Nov;307(2):505-17. Epub 2003 Sep 9.


15-Deoxy-delta12,14-PGJ2 inhibits IL-6-induced Stat3 phosphorylation in lymphocytes.

Kim HJ, Rho YH, Choi SJ, Lee YH, Cheon H, Um JW, Sohn J, Song GG, Ji JD.

Exp Mol Med. 2005 Jun 30;37(3):179-85.


Possible involvement of 15-deoxy-Δ(12,14) -prostaglandin J2 in the development of leptin resistance.

Hosoi T, Matsuzaki S, Miyahara T, Shimizu K, Hasegawa Y, Ozawa K.

J Neurochem. 2015 May;133(3):343-51. doi: 10.1111/jnc.13057. Epub 2015 Mar 2.

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