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Rationale and design of the AngeLmed for Early Recognition and Treatment of STEMI trial: a randomized, prospective clinical investigation.

Gibson MC, Krucoff M, Fischell D, Fischell TA, Keenan D, Abueg C, Patel C, Holmes D.

Am Heart J. 2014 Aug;168(2):168-74. doi: 10.1016/j.ahj.2014.05.008. Epub 2014 May 24.


Initial clinical results using intracardiac electrogram monitoring to detect and alert patients during coronary plaque rupture and ischemia.

Fischell TA, Fischell DR, Avezum A, John MS, Holmes D, Foster M 3rd, Kovach R, Medeiros P, Piegas L, Guimaraes H, Gibson CM.

J Am Coll Cardiol. 2010 Sep 28;56(14):1089-98. doi: 10.1016/j.jacc.2010.04.053.


Design and rationale of the ANALYZE ST study: a prospective, nonrandomized, multicenter ST monitoring study to detect acute coronary syndrome events in implantable cardioverter-defibrillator patients.

Gibson CM, Krucoff M, Kirtane AJ, Rao SV, Mackall JA, Matthews R, Saba S, Waksman R, Holmes D.

Am Heart J. 2014 Oct;168(4):424-429.e1. doi: 10.1016/j.ahj.2014.05.010. Epub 2014 Jun 2.


The Guardian: an implantable system for chronic ambulatory monitoring of acute myocardial infarction.

Hopenfeld B, John MS, Fischell DR, Medeiros P, Guimarães HP, Piegas LS.

J Electrocardiol. 2009 Nov-Dec;42(6):481-6. doi: 10.1016/j.jelectrocard.2009.06.017. Epub 2009 Jul 24. Review.


Rationale and design of EXPLORE: a randomized, prospective, multicenter trial investigating the impact of recanalization of a chronic total occlusion on left ventricular function in patients after primary percutaneous coronary intervention for acute ST-elevation myocardial infarction.

van der Schaaf RJ, Claessen BE, Hoebers LP, Verouden NJ, Koolen JJ, Suttorp MJ, Barbato E, Bax M, Strauss BH, Olivecrona GK, Tuseth V, Glogar D, Råmunddal T, Tijssen JG, Piek JJ, Henriques JP; EXPLORE investigators.

Trials. 2010 Sep 21;11:89. doi: 10.1186/1745-6215-11-89.


Primary Angioplasty for the Treatment of Acute ST-Segment Elevated Myocardial Infarction: An Evidence-Based Analysis.

Health Quality Ontario.

Ont Health Technol Assess Ser. 2004;4(10):1-65. Epub 2004 Aug 1.


Endovascular radiofrequency ablation for varicose veins: an evidence-based analysis.

Health Quality Ontario.

Ont Health Technol Assess Ser. 2011;11(1):1-93. Epub 2011 Feb 1.


Design and rationale of the AngioSeal versus the Radial approach In acute coronary SyndromE (ARISE) trial: a randomized comparison of a vascular closure device versus the radial approach to prevent vascular access site complications in non-ST-segment elevation acute coronary syndrome patients.

de Andrade PB, E Mattos LA, Tebet MA, Rinaldi FS, Esteves VC, Nogueira EF, França JÍ, de Andrade MV, Barbosa RA, Labrunie A, Abizaid AA, Sousa AG.

Trials. 2013 Dec 18;14:435. doi: 10.1186/1745-6215-14-435.


Rationale and design of the EMBRACE STEMI study: a phase 2a, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability and efficacy of intravenous Bendavia on reperfusion injury in patients treated with standard therapy including primary percutaneous coronary intervention and stenting for ST-segment elevation myocardial infarction.

Chakrabarti AK, Feeney K, Abueg C, Brown DA, Czyz E, Tendera M, Janosi A, Giugliano RP, Kloner RA, Weaver WD, Bode C, Godlewski J, Merkely B, Gibson CM.

Am Heart J. 2013 Apr;165(4):509-514.e7. doi: 10.1016/j.ahj.2012.12.008. Epub 2013 Feb 15.


Prospective multicenter randomized trial comparing physician versus patient transfer for primary percutaneous coronary intervention in acute ST-segment elevation myocardial infarction.

Zhang Q, Zhang RY, Qiu JP, Zhang JF, Wang XL, Jiang L, Liao ML, Zhang JS, Hu J, Yang ZK, Shen WF.

Chin Med J (Engl). 2008 Mar 20;121(6):485-91.


Association of onset to balloon and door to balloon time with long term clinical outcome in patients with ST elevation acute myocardial infarction having primary percutaneous coronary intervention: observational study.

Shiomi H, Nakagawa Y, Morimoto T, Furukawa Y, Nakano A, Shirai S, Taniguchi R, Yamaji K, Nagao K, Suyama T, Mitsuoka H, Araki M, Takashima H, Mizoguchi T, Eisawa H, Sugiyama S, Kimura T; CREDO-Kyoto AMI investigators.

BMJ. 2012 May 23;344:e3257. doi: 10.1136/bmj.e3257.


Long-term cardiovascular mortality after procedure-related or spontaneous myocardial infarction in patients with non-ST-segment elevation acute coronary syndrome: a collaborative analysis of individual patient data from the FRISC II, ICTUS, and RITA-3 trials (FIR).

Damman P, Wallentin L, Fox KA, Windhausen F, Hirsch A, Clayton T, Pocock SJ, Lagerqvist B, Tijssen JG, de Winter RJ.

Circulation. 2012 Jan 31;125(4):568-76. doi: 10.1161/CIRCULATIONAHA.111.061663. Epub 2011 Dec 23.


Association between intraprocedural thrombotic events and adverse outcomes after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (a Harmonizing Outcomes With RevasculariZatiON and Stents in Acute Myocardial Infarction [HORIZONS-AMI] Substudy).

Kirtane AJ, Sandhu P, Mehran R, McEntegart M, Cristea E, Brener SJ, Xu K, Fahy M, Généreux P, Wessler JD, Stone GW.

Am J Cardiol. 2014 Jan 1;113(1):36-43. doi: 10.1016/j.amjcard.2013.08.034. Epub 2013 Oct 2.


Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes.

Bosch X, Marrugat J, Sanchis J.

Cochrane Database Syst Rev. 2013 Nov 8;11:CD002130. doi: 10.1002/14651858.CD002130.pub4. Review.


Primary angioplasty and routine utilization of thrombus aspiration devices: feasibility and results in a consecutive series of 486 patients.

Varbella F, Gagnor A, Luceri S, Bongioanni S, Nannini C, Masi AS, Tripodi R, Pron PG, Mainardi L, Badalì A, Conte MR.

J Cardiovasc Med (Hagerstown). 2007 Apr;8(4):258-64.

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