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Items: 1 to 20 of 124

1.

Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs.

Matok I, Clark S, Caritis S, Miodovnik M, Umans JG, Hankins G, Mattison DR, Koren G.

J Clin Pharmacol. 2014 Dec;54(12):1429-33. doi: 10.1002/jcph.369. Epub 2014 Aug 7.

PMID:
25052410
2.

Systemic bioavailability and pharmacokinetics of the doxylamine-pyridoxine delayed-release combination (Diclectin).

Gill SK, Garcia-Bournissen F, Koren G.

Ther Drug Monit. 2011 Feb;33(1):115-9. doi: 10.1097/FTD.0b013e3181ff8bc5.

PMID:
21079545
3.

Comparing pyridoxine and doxylamine succinate-pyridoxine HCl for nausea and vomiting of pregnancy: A matched, controlled cohort study.

Pope E, Maltepe C, Koren G.

J Clin Pharmacol. 2015 Jul;55(7):809-14. doi: 10.1002/jcph.480. Epub 2015 Mar 27.

PMID:
25663469
4.

Comparing the pharmacokinetics of doxylamine/pyridoxine delayed-release combination in nonpregnant women of reproductive age and women in the first trimester of pregnancy.

Matok I, Clark S, Caritis S, Miodovnik M, Umans J, Hankins G, Koren G.

J Clin Pharmacol. 2013 Mar;53(3):334-8. doi: 10.1177/0091270012445207. Epub 2013 Jan 24.

PMID:
23444286
5.

Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy?

Persaud N, Chin J, Walker M.

J Obstet Gynaecol Can. 2014 Apr;36(4):343-8.

PMID:
24798673
7.

A new pharmacologic treatment for nausea and vomiting of pregnancy.

Fantasia HC.

Nurs Womens Health. 2014 Feb-Mar;18(1):73-7. doi: 10.1111/1751-486X.12096. Review.

PMID:
24548499
8.

FDA approval of doxylamine-pyridoxine therapy for use in pregnancy.

Slaughter SR, Hearns-Stokes R, van der Vlugt T, Joffe HV.

N Engl J Med. 2014 Mar 20;370(12):1081-3. doi: 10.1056/NEJMp1316042. No abstract available.

9.

Sex differences in the pharmacokinetics and bioequivalence of the delayed-release combination of doxylamine succinate-pyridoxine hydrochloride; implications for pharmacotherapy in pregnancy.

Koren G, Vranderick M, Gill SK, Macleod S.

J Clin Pharmacol. 2013 Dec;53(12):1268-76. doi: 10.1002/jcph.184. Epub 2013 Oct 10.

PMID:
24123059
10.

Characteristics of women with nausea and vomiting of pregnancy who chose to continue compassionate use of placebo after a randomised trial.

Matok I, Umans J, Feghali MN, Clark S, Caritis S, Miodovnik M, Hankins G, Mattison DR, Nordeng H, Koren G.

J Obstet Gynaecol. 2013 Aug;33(6):557-60. doi: 10.3109/01443615.2013.774327.

PMID:
23919849
11.

Critical appraisal of drug therapy for nausea and vomiting of pregnancy: II. Efficacy and safety of diclectin (doxylamine-B6).

Bishai R, Mazzotta P, Atanackovic G, Levichek Z, Pole M, Magee LA, Koren G.

Can J Clin Pharmacol. 2000 Autumn;7(3):138-43. Review.

PMID:
11044759
12.

Treating morning sickness in the United States--changes in prescribing are needed.

Koren G.

Am J Obstet Gynecol. 2014 Dec;211(6):602-6. doi: 10.1016/j.ajog.2014.08.017. Epub 2014 Aug 20.

13.

The delayed-release combination of doxylamine and pyridoxine (Diclegis®/Diclectin ®) for the treatment of nausea and vomiting of pregnancy.

Madjunkova S, Maltepe C, Koren G.

Paediatr Drugs. 2014 Jun;16(3):199-211. doi: 10.1007/s40272-014-0065-5. Review.

15.

Effectiveness of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: a randomized placebo controlled trial.

Koren G, Clark S, Hankins GD, Caritis SN, Miodovnik M, Umans JG, Mattison DR.

Am J Obstet Gynecol. 2010 Dec;203(6):571.e1-7. doi: 10.1016/j.ajog.2010.07.030. Epub 2010 Sep 16.

PMID:
20843504
16.

Preventing recurrence of severe morning sickness.

Koren G, Maltepe C.

Can Fam Physician. 2006 Dec;52(12):1545-6.

17.

Diclectin therapy for nausea and vomiting of pregnancy: effects of optimal dosing.

Boskovic R, Einarson A, Maltepe C, Wolpin J, Koren G.

J Obstet Gynaecol Can. 2003 Oct;25(10):830-3.

PMID:
14532951
18.

Maternal safety of the delayed-release doxylamine and pyridoxine combination for nausea and vomiting of pregnancy; a randomized placebo controlled trial.

Koren G, Clark S, Hankins GD, Caritis SN, Umans JG, Miodovnik M, Mattison DR, Matok I.

BMC Pregnancy Childbirth. 2015 Mar 18;15:59. doi: 10.1186/s12884-015-0488-1.

19.

Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial.

Oliveira LG, Capp SM, You WB, Riffenburgh RH, Carstairs SD.

Obstet Gynecol. 2014 Oct;124(4):735-42. doi: 10.1097/AOG.0000000000000479.

PMID:
25198265
20.

Diclegis: return of a medication.

Hansen KA.

S D Med. 2013 Dec;66(12):495. No abstract available.

PMID:
24527546
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