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Results: 1 to 20 of 108

1.

Function of inhibitory micronetworks is spared by Na+ channel-acting anticonvulsant drugs.

Pothmann L, Müller C, Averkin RG, Bellistri E, Miklitz C, Uebachs M, Remy S, Menendez de la Prida L, Beck H.

J Neurosci. 2014 Jul 16;34(29):9720-35. doi: 10.1523/JNEUROSCI.2395-13.2014.

PMID:
25031410
[PubMed - indexed for MEDLINE]
Free Article
2.

Anticonvulsant pharmacology of voltage-gated Na+ channels in hippocampal neurons of control and chronically epileptic rats.

Remy S, Urban BW, Elger CE, Beck H.

Eur J Neurosci. 2003 Jun;17(12):2648-58.

PMID:
12823472
[PubMed - indexed for MEDLINE]
3.
4.

Inhibitory effects of levetiracetam on the high-voltage-activated L-type Ca²⁺ channels in hippocampal CA3 neurons of spontaneously epileptic rat (SER).

Yan HD, Ishihara K, Seki T, Hanaya R, Kurisu K, Arita K, Serikawa T, Sasa M.

Brain Res Bull. 2013 Jan;90:142-8. doi: 10.1016/j.brainresbull.2012.10.006. Epub 2012 Oct 27.

PMID:
23107646
[PubMed - indexed for MEDLINE]
5.

Diminished response of CA1 neurons to antiepileptic drugs in chronic epilepsy.

Schaub C, Uebachs M, Beck H.

Epilepsia. 2007 Jul;48(7):1339-50. Epub 2007 Apr 18. Erratum in: Epilepsia. 2008 Jan;49(1):187.

PMID:
17441992
[PubMed - indexed for MEDLINE]
6.

Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin.

Thomas EA, Petrou S.

Epilepsia. 2013 Jul;54(7):1195-202. doi: 10.1111/epi.12172. Epub 2013 Apr 8.

PMID:
23566163
[PubMed - indexed for MEDLINE]
7.

Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel beta subunits via paradoxical effects on persistent sodium currents.

Uebachs M, Opitz T, Royeck M, Dickhof G, Horstmann MT, Isom LL, Beck H.

J Neurosci. 2010 Jun 23;30(25):8489-501. doi: 10.1523/JNEUROSCI.1534-10.2010.

PMID:
20573896
[PubMed - indexed for MEDLINE]
Free Article
8.

Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).

Peng BW, Justice JA, Zhang K, He XH, Sanchez RM.

Neuropsychopharmacology. 2010 Jan;35(2):464-72. doi: 10.1038/npp.2009.150. Epub .

PMID:
19776733
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The synergistic inhibitory actions of oxcarbazepine on voltage-gated sodium and potassium currents in differentiated NG108-15 neuronal cells and model neurons.

Huang CW, Huang CC, Lin MW, Tsai JJ, Wu SN.

Int J Neuropsychopharmacol. 2008 Aug;11(5):597-610. doi: 10.1017/S1461145707008346. Epub 2008 Jan 10.

PMID:
18184444
[PubMed - indexed for MEDLINE]
10.

Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus.

Caeser M, Evans ML, Benham CD.

Neurosci Lett. 1999 Aug 13;271(1):57-60.

PMID:
10471213
[PubMed - indexed for MEDLINE]
11.

Seeking a mechanism of action for the novel anticonvulsant lacosamide.

Errington AC, Coyne L, Stöhr T, Selve N, Lees G.

Neuropharmacology. 2006 Jun;50(8):1016-29. Epub 2006 Apr 18.

PMID:
16620882
[PubMed - indexed for MEDLINE]
12.

V102862 (Co 102862): a potent, broad-spectrum state-dependent blocker of mammalian voltage-gated sodium channels.

Ilyin VI, Hodges DD, Whittemore ER, Carter RB, Cai SX, Woodward RM.

Br J Pharmacol. 2005 Mar;144(6):801-12.

PMID:
15778702
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Kinetic changes and modulation by carbamazepine on voltage-gated sodium channels in rat CA1 neurons after epilepsy.

Sun GC, Werkman TR, Wadman WJ.

Acta Pharmacol Sin. 2006 Dec;27(12):1537-46.

PMID:
17112406
[PubMed - indexed for MEDLINE]
Free Article
14.

Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.

Schumacher TB, Beck H, Steinhäuser C, Schramm J, Elger CE.

Epilepsia. 1998 Apr;39(4):355-63.

PMID:
9578025
[PubMed - indexed for MEDLINE]
15.

Inhibitory effects of the antiepileptic drug ethosuximide on G protein-activated inwardly rectifying K+ channels.

Kobayashi T, Hirai H, Iino M, Fuse I, Mitsumura K, Washiyama K, Kasai S, Ikeda K.

Neuropharmacology. 2009 Feb;56(2):499-506. doi: 10.1016/j.neuropharm.2008.10.003. Epub 2008 Oct 17.

PMID:
18977371
[PubMed - indexed for MEDLINE]
16.
17.

Effects of carbamazepine and amitriptyline on tetrodotoxinresistant Na+ channels in immature rat trigeminal ganglion neurons.

Hur YK, Choi IS, Cho JH, Park EJ, Choi JK, Choi BJ, Jang IS.

Arch Pharm Res. 2008 Feb;31(2):178-82.

PMID:
18365687
[PubMed - indexed for MEDLINE]
18.

The relationship between sodium channel inhibition and anticonvulsant activity in a model of generalised seizure in the rat.

Large CH, Kalinichev M, Lucas A, Carignani C, Bradford A, Garbati N, Sartori I, Austin NE, Ruffo A, Jones DN, Alvaro G, Read KD.

Epilepsy Res. 2009 Jul;85(1):96-106. doi: 10.1016/j.eplepsyres.2009.02.018. Epub 2009 Mar 28.

PMID:
19329281
[PubMed - indexed for MEDLINE]
19.

Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na+ channels and with native Na+ channels in rat hippocampal neurones.

Xie X, Lancaster B, Peakman T, Garthwaite J.

Pflugers Arch. 1995 Jul;430(3):437-46.

PMID:
7491269
[PubMed - indexed for MEDLINE]
20.

Anticonvulsant activity of BmK AS, a sodium channel site 4-specific modulator.

Zhao R, Weng CC, Feng Q, Chen L, Zhang XY, Zhu HY, Wang Y, Ji YH.

Epilepsy Behav. 2011 Feb;20(2):267-76. doi: 10.1016/j.yebeh.2010.12.006. Epub 2011 Jan 15.

PMID:
21239233
[PubMed - indexed for MEDLINE]

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