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Items: 1 to 20 of 113

1.

Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.

Sahin E, Haubenwallner S, Kuttke M, Kollmann I, Halfmann A, Dohnal AM, Chen L, Cheng P, Hoesel B, Einwallner E, Brunner J, Kral JB, Schrottmaier WC, Thell K, Saferding V, Blüml S, Schabbauer G.

J Immunol. 2014 Aug 15;193(4):1717-27. doi: 10.4049/jimmunol.1302167. Epub 2014 Jul 11. Erratum in: J Immunol. 2014 Nov 15;193(10):5350. Dohnal, Alexander B [Corrected to Dohnal, Alexander M].

2.

HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: regulation of TLR4 innate responses through PI3K/PTEN signaling.

Ke B, Shen XD, Ji H, Kamo N, Gao F, Freitas MC, Busuttil RW, Kupiec-Weglinski JW.

J Hepatol. 2012 Feb;56(2):359-66. doi: 10.1016/j.jhep.2011.05.023. Epub 2011 Jul 12.

3.

The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages.

Cao X, Wei G, Fang H, Guo J, Weinstein M, Marsh CB, Ostrowski MC, Tridandapani S.

J Immunol. 2004 Apr 15;172(8):4851-7.

4.

The role of JAK-3 in regulating TLR-mediated inflammatory cytokine production in innate immune cells.

Wang H, Brown J, Gao S, Liang S, Jotwani R, Zhou H, Suttles J, Scott DA, Lamont RJ.

J Immunol. 2013 Aug 1;191(3):1164-74. doi: 10.4049/jimmunol.1203084. Epub 2013 Jun 24.

5.

Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses.

Chi H, Barry SP, Roth RJ, Wu JJ, Jones EA, Bennett AM, Flavell RA.

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2274-9. Epub 2006 Feb 6.

6.

Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages.

Luyendyk JP, Schabbauer GA, Tencati M, Holscher T, Pawlinski R, Mackman N.

J Immunol. 2008 Mar 15;180(6):4218-26.

7.

β-catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury.

Ke B, Shen XD, Kamo N, Ji H, Yue S, Gao F, Busuttil RW, Kupiec-Weglinski JW.

Hepatology. 2013 Mar;57(3):1203-14. doi: 10.1002/hep.26100. Epub 2013 Feb 7.

8.

Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression.

Baker AK, Wang R, Mackman N, Luyendyk JP.

Mol Immunol. 2009 Jul;46(11-12):2249-55. doi: 10.1016/j.molimm.2009.04.011. Epub 2009 May 17.

9.

Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain.

Medina EA, Morris IR, Berton MT.

J Immunol. 2010 Dec 15;185(12):7562-72. doi: 10.4049/jimmunol.0903790. Epub 2010 Nov 22.

10.
11.

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.

El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR.

J Immunol. 2014 Jul 15;193(2):597-609. doi: 10.4049/jimmunol.1303048. Epub 2014 Jun 13.

12.

Zinc finger protein 64 promotes Toll-like receptor-triggered proinflammatory and type I interferon production in macrophages by enhancing p65 subunit activation.

Wang C, Liu X, Liu Y, Zhang Q, Yao Z, Huang B, Zhang P, Li N, Cao X.

J Biol Chem. 2013 Aug 23;288(34):24600-8. doi: 10.1074/jbc.M113.473397. Epub 2013 Jul 15.

13.

PTEN-mediated Akt/β-catenin/Foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury.

Kamo N, Ke B, Busuttil RW, Kupiec-Weglinski JW.

Hepatology. 2013 Jan;57(1):289-98. doi: 10.1002/hep.25958. Epub 2012 Dec 4.

14.

Recent advances in the genetic analysis of PTEN and PI3K innate immune properties.

Günzl P, Schabbauer G.

Immunobiology. 2008;213(9-10):759-65. doi: 10.1016/j.imbio.2008.07.028. Epub 2008 Sep 11. Review.

PMID:
18926291
15.

Effective clearance of intracellular Leishmania major in vivo requires Pten in macrophages.

Kuroda S, Nishio M, Sasaki T, Horie Y, Kawahara K, Sasaki M, Natsui M, Matozaki T, Tezuka H, Ohteki T, Förster I, Mak TW, Nakano T, Suzuki A.

Eur J Immunol. 2008 May;38(5):1331-40. doi: 10.1002/eji.200737302.

16.

Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation.

Berlato C, Cassatella MA, Kinjyo I, Gatto L, Yoshimura A, Bazzoni F.

J Immunol. 2002 Jun 15;168(12):6404-11.

17.

Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia.

Panda SK, Kumar S, Tupperwar NC, Vaidya T, George A, Rath S, Bal V, Ravindran B.

PLoS Pathog. 2012;8(5):e1002717. doi: 10.1371/journal.ppat.1002717. Epub 2012 May 24.

18.

Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.

Sahin E, Brunner JS, Kral JB, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal AM, Krönke G, Blüml S, Schabbauer G.

J Immunol. 2015 Sep 15;195(6):2560-70. doi: 10.4049/jimmunol.1402511. Epub 2015 Aug 5.

PMID:
26246144
19.

Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation.

Günzl P, Bauer K, Hainzl E, Matt U, Dillinger B, Mahr B, Knapp S, Binder BR, Schabbauer G.

J Leukoc Biol. 2010 Dec;88(6):1259-69. doi: 10.1189/jlb.0110001. Epub 2010 Sep 30.

20.

A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages.

Goldsmith M, Avni D, Levy-Rimler G, Mashiach R, Ernst O, Levi M, Webb B, Meijler MM, Gray NS, Rosen H, Zor T.

Immunology. 2009 May;127(1):103-15. doi: 10.1111/j.1365-2567.2008.02928.x.

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