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Items: 1 to 20 of 104

1.

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundstrom J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borinskaya SA, Finan C, Shah S, Kuchenbaecker KB, Shah T, Engmann J, Folkersen L, Eriksson P, Ricceri F, Melander O, Sacerdote C, Gamble DM, Rayaprolu S, Ross OA, McLachlan S, Vikhireva O, Sluijs I, Scott RA, Adamkova V, Flicker L, Bockxmeer FM, Power C, Marques-Vidal P, Meade T, Marmot MG, Ferro JM, Paulos-Pinheiro S, Humphries SE, Talmud PJ, Mateo Leach I, Verweij N, Linneberg A, Skaaby T, Doevendans PA, Cramer MJ, van der Harst P, Klungel OH, Dowling NF, Dominiczak AF, Kumari M, Nicolaides AN, Weikert C, Boeing H, Ebrahim S, Gaunt TR, Price JF, Lannfelt L, Peasey A, Kubinova R, Pajak A, Malyutina S, Voevoda MI, Tamosiunas A, Maitland-van der Zee AH, Norman PE, Hankey GJ, Bergmann MM, Hofman A, Franco OH, Cooper J, Palmen J, Spiering W, de Jong PA, Kuh D, Hardy R, Uitterlinden AG, Ikram MA, Ford I, Hyppönen E, Almeida OP, Wareham NJ, Khaw KT, Hamsten A, Husemoen LL, Tjønneland A, Tolstrup JS, Rimm E, Beulens JW, Verschuren WM, Onland-Moret NC, Hofker MH, Wannamethee SG, Whincup PH, Morris R, Vicente AM, Watkins H, Farrall M, Jukema JW, Meschia J, Cupples LA, Sharp SJ, Fornage M, Kooperberg C, LaCroix AZ, Dai JY, Lanktree MB, Siscovick DS, Jorgenson E, Spring B, Coresh J, Li YR, Buxbaum SG, Schreiner PJ, Ellison RC, Tsai MY, Patel SR, Redline S, Johnson AD, Hoogeveen RC, Hakonarson H, Rotter JI, Boerwinkle E, de Bakker PI, Kivimaki M, Asselbergs FW, Sattar N, Lawlor DA, Whittaker J, Davey Smith G, Mukamal K, Psaty BM, Wilson JG, Lange LA, Hamidovic A, Hingorani AD, Nordestgaard BG, Bobak M, Leon DA, Langenberg C, Palmer TM, Reiner AP, Keating BJ, Dudbridge F, Casas JP; InterAct Consortium.

BMJ. 2014 Jul 10;349:g4164. doi: 10.1136/bmj.g4164.

2.

Alcohol consumption mediates the relationship between ADH1B and DSM-IV alcohol use disorder and criteria.

Kilcoyne B, Shmulewitz D, Meyers JL, Aharonovich E, Greenstein E, Frisch A, Weizman A, Spivak B, Edenberg HJ, Gelernter J, Hasin DS.

J Stud Alcohol Drugs. 2014 Jul;75(4):635-42.

3.

Alcohol consumption and cognitive impairment in older men: a mendelian randomization study.

Almeida OP, Hankey GJ, Yeap BB, Golledge J, Flicker L.

Neurology. 2014 Mar 25;82(12):1038-44. doi: 10.1212/WNL.0000000000000255. Epub 2014 Feb 19.

4.

Alcohol consumption and cognitive performance: a Mendelian randomization study.

Kumari M, Holmes MV, Dale CE, Hubacek JA, Palmer TM, Pikhart H, Peasey A, Britton A, Horvat P, Kubinova R, Malyutina S, Pajak A, Tamosiunas A, Shankar A, Singh-Manoux A, Voevoda M, Kivimaki M, Hingorani AD, Marmot MG, Casas JP, Bobak M.

Addiction. 2014 Sep;109(9):1462-71. doi: 10.1111/add.12568. Epub 2014 Jul 1.

5.

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits.

Silverwood RJ, Holmes MV, Dale CE, Lawlor DA, Whittaker JC, Smith GD, Leon DA, Palmer T, Keating BJ, Zuccolo L, Casas JP, Dudbridge F; Alcohol-ADH1B Consortium.

Int J Epidemiol. 2014 Dec;43(6):1781-90. doi: 10.1093/ije/dyu187. Epub 2014 Sep 5.

6.

A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women.

Zuccolo L, Fitz-Simon N, Gray R, Ring SM, Sayal K, Smith GD, Lewis SJ.

Hum Mol Genet. 2009 Nov 15;18(22):4457-66. doi: 10.1093/hmg/ddp388. Epub 2009 Aug 17.

7.

Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample.

Meyers JL, Shmulewitz D, Aharonovich E, Waxman R, Frisch A, Weizman A, Spivak B, Edenberg HJ, Gelernter J, Hasin DS.

Alcohol Clin Exp Res. 2013 Nov;37(11):1872-81. doi: 10.1111/acer.12176. Epub 2013 Jul 29.

8.

Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study.

Ferrari P, McKay JD, Jenab M, Brennan P, Canzian F, Vogel U, Tjønneland A, Overvad K, Tolstrup JS, Boutron-Ruault MC, Clavel-Chapelon F, Morois S, Kaaks R, Boeing H, Bergmann M, Trichopoulou A, Katsoulis M, Trichopoulos D, Krogh V, Panico S, Sacerdote C, Palli D, Tumino R, Peeters PH, van Gils CH, Bueno-de-Mesquita B, Vrieling A, Lund E, Hjartåker A, Agudo A, Suarez LR, Arriola L, Chirlaque MD, Ardanaz E, Sánchez MJ, Manjer J, Lindkvist B, Hallmans G, Palmqvist R, Allen N, Key T, Khaw KT, Slimani N, Rinaldi S, Romieu I, Boffetta P, Romaguera D, Norat T, Riboli E.

Eur J Clin Nutr. 2012 Dec;66(12):1303-8. doi: 10.1038/ejcn.2012.173. Epub 2012 Nov 14.

PMID:
23149980
9.

Alcohol dehydrogenase-1B Arg47His polymorphism and upper aerodigestive tract cancer risk: a meta-analysis including 24,252 subjects.

Guo H, Zhang G, Mai R.

Alcohol Clin Exp Res. 2012 Feb;36(2):272-8. doi: 10.1111/j.1530-0277.2011.01621.x. Epub 2011 Sep 6. Review.

PMID:
21895720
10.

Prenatal alcohol exposure and childhood atopic disease: a Mendelian randomization approach.

Shaheen SO, Rutterford C, Zuccolo L, Ring SM, Davey Smith G, Holloway JW, Henderson AJ.

J Allergy Clin Immunol. 2014 Jan;133(1):225-32.e1-5. doi: 10.1016/j.jaci.2013.04.051. Epub 2013 Jun 24.

11.

The role of ALDH2 and ADH1B polymorphism in alcohol consumption and stroke in Han Chinese.

Yao CT, Cheng CA, Wang HK, Chiu SW, Chen YC, Wang MF, Yin SJ, Peng GS.

Hum Genomics. 2011 Oct;5(6):569-76.

12.

Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers.

Meyers JL, Shmulewitz D, Wall MM, Keyes KM, Aharonovich E, Spivak B, Weizman A, Frisch A, Edenberg HJ, Gelernter J, Grant BF, Hasin D.

Addict Biol. 2015 Jan;20(1):205-14. doi: 10.1111/adb.12102. Epub 2013 Oct 24.

13.

The triangular association of ADH1B genetic polymorphism, alcohol consumption and the risk of depression in older men.

Almeida OP, Hankey GJ, Yeap BB, Golledge J, Flicker L.

Mol Psychiatry. 2014 Sep;19(9):995-1000. doi: 10.1038/mp.2013.117. Epub 2013 Sep 10.

PMID:
24018899
14.

Genetic polymorphisms of ADH1B, ADH1C and ALDH2, alcohol consumption, and the risk of gastric cancer: the Japan Public Health Center-based prospective study.

Hidaka A, Sasazuki S, Matsuo K, Ito H, Sawada N, Shimazu T, Yamaji T, Iwasaki M, Inoue M, Tsugane S; JPHC Study Group.

Carcinogenesis. 2015 Feb;36(2):223-31. doi: 10.1093/carcin/bgu244. Epub 2014 Dec 18.

15.

ADH1B polymorphism, alcohol consumption, and binge drinking in Slavic Caucasians: results from the Czech HAPIEE study.

Hubacek JA, Pikhart H, Peasey A, Kubinova R, Bobak M.

Alcohol Clin Exp Res. 2012 May;36(5):900-5. doi: 10.1111/j.1530-0277.2011.01680.x. Epub 2011 Dec 7.

16.

Alcohol dehydrogenase-1B genotype (rs1229984) is a strong determinant of the relationship between body weight and alcohol intake in Japanese alcoholic men.

Yokoyama A, Yokoyama T, Matsui T, Mizukami T, Matsushita S, Higuchi S, Maruyama K.

Alcohol Clin Exp Res. 2013 Jul;37(7):1123-32. doi: 10.1111/acer.12069. Epub 2013 Feb 15.

PMID:
23414439
17.

Mendelian randomisation meta-analysis sheds doubt on protective associations between 'moderate' alcohol consumption and coronary heart disease.

Chikritzhs TN, Naimi TS, Stockwell TR, Liang W.

Evid Based Med. 2015 Feb;20(1):38. doi: 10.1136/ebmed-2014-110086. Epub 2014 Nov 4. No abstract available.

PMID:
25371403
18.

Alcohol consumption, genetic variants in alcohol deydrogenases, and risk of cardiovascular diseases: a prospective study and meta-analysis.

Drogan D, Sheldrick AJ, Schütze M, Knüppel S, Andersohn F, di Giuseppe R, Herrmann B, Willich SN, Garbe E, Bergmann MM, Boeing H, Weikert C.

PLoS One. 2012;7(2):e32176. doi: 10.1371/journal.pone.0032176. Epub 2012 Feb 21.

19.

ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.

Bierut LJ, Goate AM, Breslau N, Johnson EO, Bertelsen S, Fox L, Agrawal A, Bucholz KK, Grucza R, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Porjesz B, Saccone NL, Schuckit M, Tischfield J, Wang JC, Foroud T, Rice JP, Edenberg HJ.

Mol Psychiatry. 2012 Apr;17(4):445-50. doi: 10.1038/mp.2011.124. Epub 2011 Oct 4.

20.

Single nucleotide polymorphisms of ADH1B, ADH1C and ALDH2 genes and esophageal cancer: a population-based case-control study in China.

Wu M, Chang SC, Kampman E, Yang J, Wang XS, Gu XP, Han RQ, Liu AM, Wallar G, Zhou JY, Kok FJ, Zhao JK, Zhang ZF.

Int J Cancer. 2013 Apr 15;132(8):1868-77. doi: 10.1002/ijc.27803. Epub 2012 Sep 28.

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