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Results: 1 to 20 of 101

1.

A constrained maximum likelihood approach to evaluate the impact of dose metric on cancer risk assessment: application to β-chloroprene.

Allen BC, Van Landingham C, Yang Y, Youk AO, Marsh GM, Esmen N, Gentry PR, Clewell HJ 3rd, Himmelstein MW.

Regul Toxicol Pharmacol. 2014 Oct;70(1):203-13. doi: 10.1016/j.yrtph.2014.07.001. Epub 2014 Jul 7.

PMID:
25010378
[PubMed - in process]
2.

PBPK models in risk assessment--A focus on chloroprene.

DeWoskin RS.

Chem Biol Interact. 2007 Mar 20;166(1-3):352-9. Epub 2007 Feb 8.

PMID:
17324392
[PubMed - indexed for MEDLINE]
3.

Kinetic modeling of beta-chloroprene metabolism: II. The application of physiologically based modeling for cancer dose response analysis.

Himmelstein MW, Carpenter SC, Evans MV, Hinderliter PM, Kenyon EM.

Toxicol Sci. 2004 May;79(1):28-37. Epub 2004 Feb 19.

PMID:
14976335
[PubMed - indexed for MEDLINE]
Free Article
4.

NTP Toxicology and Carcinogenesis Studies of Chloroprene (CAS No. 126-99-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies).

National Toxicology Program.

Natl Toxicol Program Tech Rep Ser. 1998 Sep;467:1-379.

PMID:
12579206
[PubMed - as supplied by publisher]
Free Article
5.

Multiple organ carcinogenicity of inhaled chloroprene (2-chloro-1,3-butadiene) in F344/N rats and B6C3F1 mice and comparison of dose-response with 1,3-butadiene in mice.

Melnick RL, Sills RC, Portier CJ, Roycroft JH, Chou BJ, Grumbein SL, Miller RA.

Carcinogenesis. 1999 May;20(5):867-78.

PMID:
10334205
[PubMed - indexed for MEDLINE]
Free Article
6.

Toxicology of 1,3-butadiene, chloroprene, and isoprene.

Hurst HE.

Rev Environ Contam Toxicol. 2007;189:131-79. Review.

PMID:
17193739
[PubMed - indexed for MEDLINE]
7.

Kinetic modeling of beta-chloroprene metabolism: I. In vitro rates in liver and lung tissue fractions from mice, rats, hamsters, and humans.

Himmelstein MW, Carpenter SC, Hinderliter PM.

Toxicol Sci. 2004 May;79(1):18-27. Epub 2004 Feb 19.

PMID:
14976339
[PubMed - indexed for MEDLINE]
Free Article
8.

Comparative carcinogenicity of 1,3-butadiene, isoprene, and chloroprene in rats and mice.

Melnick RL, Sills RC.

Chem Biol Interact. 2001 Jun 1;135-136:27-42. Review.

PMID:
11397379
[PubMed - indexed for MEDLINE]
9.

The metabolism of beta-chloroprene: preliminary in-vitro studies using liver microsomes.

Himmelstein MW, Carpenter SC, Hinderliter PM, Snow TA, Valentine R.

Chem Biol Interact. 2001 Jun 1;135-136:267-84.

PMID:
11397396
[PubMed - indexed for MEDLINE]
10.

1,3-Butadiene, isoprene and chloroprene: reviews by the IARC monographs programme, outstanding issues, and research priorities in epidemiology.

Rice JM, Boffetta P.

Chem Biol Interact. 2001 Jun 1;135-136:11-26. Review.

PMID:
11397378
[PubMed - indexed for MEDLINE]
11.

Kinetic modeling of β-chloroprene metabolism: Probabilistic in vitro-in vivo extrapolation of metabolism in the lung, liver and kidneys of mice, rats and humans.

Yang Y, Himmelstein MW, Clewell HJ.

Toxicol In Vitro. 2012 Sep;26(6):1047-55. doi: 10.1016/j.tiv.2012.04.004. Epub 2012 Apr 19.

PMID:
22543297
[PubMed - indexed for MEDLINE]
12.

Genotoxicity of 1,3-butadiene and its epoxy intermediates.

Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF; Health Review Committee.

Res Rep Health Eff Inst. 2009 Aug;(144):3-79.

PMID:
20017413
[PubMed - indexed for MEDLINE]
13.

Chloroprene: overview of studies under consideration for the development of an IRIS assessment.

Pagan I.

Chem Biol Interact. 2007 Mar 20;166(1-3):341-51. Epub 2006 Dec 12.

PMID:
17234169
[PubMed - indexed for MEDLINE]
14.

Overview of the acute, subchronic, reproductive, developmental and genetic toxicology of beta-chloroprene.

Valentine R, Himmelstein MW.

Chem Biol Interact. 2001 Jun 1;135-136:81-100. Review.

PMID:
11397383
[PubMed - indexed for MEDLINE]
15.

Toxicity of inhaled chloroprene (2-chloro-1,3-butadiene) in F344 rats and B6C3F(1) mice.

Melnick RL, Elwell MR, Roycroft JH, Chou BJ, Ragan HA, Miller RA.

Toxicology. 1996 Apr 15;108(1-2):79-91.

PMID:
8644121
[PubMed - indexed for MEDLINE]
16.

Dosimetric adjustments for interspecies extrapolation of inhaled poorly soluble particles (PSP).

Jarabek AM, Asgharian B, Miller FJ.

Inhal Toxicol. 2005 Jun-Jul;17(7-8):317-34.

PMID:
16020031
[PubMed - indexed for MEDLINE]
17.

Cross-species transcriptomic analysis of mouse and rat lung exposed to chloroprene.

Thomas RS, Himmelstein MW, Clewell HJ 3rd, Yang Y, Healy E, Black MB, Andersen ME.

Toxicol Sci. 2013 Feb;131(2):629-40. doi: 10.1093/toxsci/kfs314. Epub 2012 Nov 3.

PMID:
23125180
[PubMed - indexed for MEDLINE]
Free Article
18.

Mortality patterns among industrial workers exposed to chloroprene and other substances. II. Mortality in relation to exposure.

Marsh GM, Youk AO, Buchanich JM, Cunningham M, Esmen NA, Hall TA, Phillips ML.

Chem Biol Interact. 2007 Mar 20;166(1-3):301-16. Epub 2006 Aug 22.

PMID:
17007827
[PubMed - indexed for MEDLINE]
20.

Insights into the toxicokinetics and toxicodynamics of 1,3-butadiene.

Bond JA, Medinsky MA.

Chem Biol Interact. 2001 Jun 1;135-136:599-614. Review.

PMID:
11397415
[PubMed - indexed for MEDLINE]

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