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Items: 1 to 20 of 102

1.

Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade.

Chen YY, Hsieh CY, Jayakumar T, Lin KH, Chou DS, Lu WJ, Hsu MJ, Sheu JR.

Sci Rep. 2014 Jul 10;4:5651. doi: 10.1038/srep05651.

2.

Andrographolide inhibits nuclear factor-κB activation through JNK-Akt-p65 signaling cascade in tumor necrosis factor-α-stimulated vascular smooth muscle cells.

Chen YY, Hsu MJ, Hsieh CY, Lee LW, Chen ZC, Sheu JR.

ScientificWorldJournal. 2014;2014:130381. doi: 10.1155/2014/130381. Epub 2014 Jul 10.

3.

Andrographolide enhances nuclear factor-kappaB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells.

Hsieh CY, Hsu MJ, Hsiao G, Wang YH, Huang CW, Chen SW, Jayakumar T, Chiu PT, Chiu YH, Sheu JR.

J Biol Chem. 2011 Feb 25;286(8):5942-55. doi: 10.1074/jbc.M110.123968. Epub 2010 Dec 17.

4.

PMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells.

Hsieh CY, Hsiao G, Hsu MJ, Wang YH, Sheu JR.

J Cell Mol Med. 2014 Jul;18(7):1278-89. doi: 10.1111/jcmm.12277. Epub 2014 Apr 13.

5.

Acrolein activates mitogen-activated protein kinase signal transduction pathways in rat vascular smooth muscle cells.

Ranganna K, Yousefipour Z, Nasif R, Yatsu FM, Milton SG, Hayes BE.

Mol Cell Biochem. 2002 Nov;240(1-2):83-98.

PMID:
12487375
6.

Glomerular VEGF resistance induced by PKCδ/SHP-1 activation and contribution to diabetic nephropathy.

Mima A, Kitada M, Geraldes P, Li Q, Matsumoto M, Mizutani K, Qi W, Li C, Leitges M, Rask-Madsen C, King GL.

FASEB J. 2012 Jul;26(7):2963-74. doi: 10.1096/fj.11-202994. Epub 2012 Apr 12.

7.

Protein kinase C delta induces apoptosis of vascular smooth muscle cells through induction of the tumor suppressor p53 by both p38-dependent and p38-independent mechanisms.

Ryer EJ, Sakakibara K, Wang C, Sarkar D, Fisher PB, Faries PL, Kent KC, Liu B.

J Biol Chem. 2005 Oct 21;280(42):35310-7. Epub 2005 Aug 23.

8.

Suppression of NF-κB signaling by andrographolide with a novel mechanism in human platelets: regulatory roles of the p38 MAPK-hydroxyl radical-ERK2 cascade.

Lu WJ, Lin KH, Hsu MJ, Chou DS, Hsiao G, Sheu JR.

Biochem Pharmacol. 2012 Oct 1;84(7):914-24. doi: 10.1016/j.bcp.2012.06.030. Epub 2012 Jul 4.

PMID:
22771630
9.

Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-κB-mediated bcl-2 activation and modulating p53-induced caspase-3 gene expression.

Pratheeshkumar P, Sheeja K, Kuttan G.

Immunopharmacol Immunotoxicol. 2012 Feb;34(1):143-51. doi: 10.3109/08923973.2011.588233. Epub 2011 Jun 20.

PMID:
21682651
10.

Sensitization of vascular smooth muscle cell to TNF-alpha-mediated death in the presence of palmitate.

Rho MC, Ah Lee K, Mi Kim S, Sik Lee C, Jeong Jang M, Kook Kim Y, Sun Lee H, Hyun Choi Y, Yong Rhim B, Kim K.

Toxicol Appl Pharmacol. 2007 May 1;220(3):311-9. Epub 2007 Feb 24.

PMID:
17399759
11.

Role of SHP-1, Kv.1.2, and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells.

Palen DI, Belmadani S, Lucchesi PA, Matrougui K.

Cardiovasc Res. 2005 Nov 1;68(2):268-77. Epub 2005 Jun 20.

12.

Ceramide mediates Ox-LDL-induced human vascular smooth muscle cell calcification via p38 mitogen-activated protein kinase signaling.

Liao L, Zhou Q, Song Y, Wu W, Yu H, Wang S, Chen Y, Ye M, Lu L.

PLoS One. 2013 Dec 16;8(12):e82379. doi: 10.1371/journal.pone.0082379. eCollection 2013.

13.

Effects of Panax notoginseng saponins on proliferation and apoptosis of vascular smooth muscle cells.

Xu L, Liu JT, Liu N, Lu PP, Pang XM.

J Ethnopharmacol. 2011 Sep 1;137(1):226-30. doi: 10.1016/j.jep.2011.05.020. Epub 2011 May 17.

PMID:
21619919
14.

Cigarette smoke extract promotes human vascular smooth muscle cell proliferation and survival through ERK1/2- and NF-κB-dependent pathways.

Chen QW, Edvinsson L, Xu CB.

ScientificWorldJournal. 2010 Nov 4;10:2139-56. doi: 10.1100/tsw.2010.201.

15.
16.

Pivotal role of tyrosine phosphatase SHP-1 in AT2 receptor-mediated apoptosis in rat fetal vascular smooth muscle cell.

Cui T, Nakagami H, Iwai M, Takeda Y, Shiuchi T, Daviet L, Nahmias C, Horiuchi M.

Cardiovasc Res. 2001 Mar;49(4):863-71.

17.

Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-kappaB-mediated survival signaling.

Leskinen MJ, Heikkilä HM, Speer MY, Hakala JK, Laine M, Kovanen PT, Lindstedt KA.

Exp Cell Res. 2006 May 1;312(8):1289-98. Epub 2006 Feb 7.

PMID:
16460729
18.

TLR 2 induces vascular smooth muscle cell migration through cAMP response element-binding protein-mediated interleukin-6 production.

Lee GL, Chang YW, Wu JY, Wu ML, Wu KK, Yet SF, Kuo CC.

Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2751-60. doi: 10.1161/ATVBAHA.112.300302. Epub 2012 Sep 20.

20.

Suppression of soluble adenylyl cyclase protects smooth muscle cells against oxidative stress-induced apoptosis.

Kumar S, Appukuttan A, Maghnouj A, Hahn S, Peter Reusch H, Ladilov Y.

Apoptosis. 2014 Jul;19(7):1069-79. doi: 10.1007/s10495-014-0989-9.

PMID:
24781801
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