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Items: 1 to 20 of 325

1.

Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo.

Park MJ, Kim DI, Lim SK, Choi JH, Kim JC, Yoon KC, Lee JB, Lee JH, Han HJ, Choi IP, Kim HC, Park SH.

J Hepatol. 2014 Nov;61(5):1151-7. doi: 10.1016/j.jhep.2014.06.032. Epub 2014 Jul 6.

PMID:
25003952
2.

Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation.

Castaño D, Larequi E, Belza I, Astudillo AM, Martínez-Ansó E, Balsinde J, Argemi J, Aragon T, Moreno-Aliaga MJ, Muntane J, Prieto J, Bustos M.

J Hepatol. 2014 May;60(5):1017-25. doi: 10.1016/j.jhep.2013.12.012. Epub 2013 Dec 19.

PMID:
24362075
3.

Chronic administration of recombinant IL-6 upregulates lipogenic enzyme expression and aggravates high-fat-diet-induced steatosis in IL-6-deficient mice.

Vida M, Gavito AL, Pavón FJ, Bautista D, Serrano A, Suarez J, Arrabal S, Decara J, Romero-Cuevas M, Rodríguez de Fonseca F, Baixeras E.

Dis Model Mech. 2015 Jul 1;8(7):721-31. doi: 10.1242/dmm.019166. Epub 2015 May 14.

4.

Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation.

Zhang X, Zhang JH, Chen XY, Hu QH, Wang MX, Jin R, Zhang QY, Wang W, Wang R, Kang LL, Li JS, Li M, Pan Y, Huang JJ, Kong LD.

Antioxid Redox Signal. 2015 Apr 1;22(10):848-70. doi: 10.1089/ars.2014.5868.

5.

Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity.

Yan F, Wang Q, Lu M, Chen W, Song Y, Jing F, Guan Y, Wang L, Lin Y, Bo T, Zhang J, Wang T, Xin W, Yu C, Guan Q, Zhou X, Gao L, Xu C, Zhao J.

J Hepatol. 2014 Dec;61(6):1358-64. doi: 10.1016/j.jhep.2014.06.037. Epub 2014 Jul 10.

PMID:
25016220
6.

PRMT3 regulates hepatic lipogenesis through direct interaction with LXRα.

Kim DI, Park MJ, Lim SK, Park JI, Yoon KC, Han HJ, Gustafsson JÅ, Lim JH, Park SH.

Diabetes. 2015 Jan;64(1):60-71. doi: 10.2337/db13-1394. Epub 2014 Sep 3.

7.

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

González-Rodríguez A, Mayoral R, Agra N, Valdecantos MP, Pardo V, Miquilena-Colina ME, Vargas-Castrillón J, Lo Iacono O, Corazzari M, Fimia GM, Piacentini M, Muntané J, Boscá L, García-Monzón C, Martín-Sanz P, Valverde ÁM.

Cell Death Dis. 2014 Apr 17;5:e1179. doi: 10.1038/cddis.2014.162.

8.

Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet.

Liu X, Henkel AS, LeCuyer BE, Schipma MJ, Anderson KA, Green RM.

Am J Physiol Gastrointest Liver Physiol. 2015 Dec 15;309(12):G965-74. doi: 10.1152/ajpgi.00132.2015. Epub 2015 Oct 15.

PMID:
26472223
9.

Thioredoxin-interacting protein (Txnip) is a critical regulator of hepatic glucose production.

Chutkow WA, Patwari P, Yoshioka J, Lee RT.

J Biol Chem. 2008 Jan 25;283(4):2397-406. Epub 2007 Nov 12.

10.

Interleukin enhancer-binding factor 3 functions as a liver receptor homologue-1 co-activator in synergy with the nuclear receptor co-activators PRMT1 and PGC-1α.

Ohno M, Komakine J, Suzuki E, Nishizuka M, Osada S, Imagawa M.

Biochem J. 2011 Aug 1;437(3):531-40. doi: 10.1042/BJ20101793.

PMID:
21554248
11.

Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats.

Wang W, Wang C, Ding XQ, Pan Y, Gu TT, Wang MX, Liu YL, Wang FM, Wang SJ, Kong LD.

Br J Pharmacol. 2013 Jul;169(6):1352-71. doi: 10.1111/bph.12226.

12.

Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation.

Andrade JM, Paraíso AF, de Oliveira MV, Martins AM, Neto JF, Guimarães AL, de Paula AM, Qureshi M, Santos SH.

Nutrition. 2014 Jul-Aug;30(7-8):915-9. doi: 10.1016/j.nut.2013.11.016. Epub 2013 Dec 4.

13.

Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.

Pan X, Wang P, Luo J, Wang Z, Song Y, Ye J, Hou X.

Endocrine. 2015 Apr;48(3):834-47. doi: 10.1007/s12020-014-0384-x. Epub 2014 Aug 20.

PMID:
25138963
14.

HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation.

Liu Y, Ma Z, Zhao C, Wang Y, Wu G, Xiao J, McClain CJ, Li X, Feng W.

Toxicol Lett. 2014 Apr 21;226(2):117-23. doi: 10.1016/j.toxlet.2014.01.033. Epub 2014 Feb 3.

PMID:
24503013
15.

Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice.

Zhu LH, Wang A, Luo P, Wang X, Jiang DS, Deng W, Zhang X, Wang T, Liu Y, Gao L, Zhang S, Zhang X, Zhang J, Li H.

J Hepatol. 2014 May;60(5):1046-54. doi: 10.1016/j.jhep.2014.01.011. Epub 2014 Jan 18.

PMID:
24445216
16.
17.

Hepatic STAMP2 alleviates high fat diet-induced hepatic steatosis and insulin resistance.

Kim HY, Park SY, Lee MH, Rho JH, Oh YJ, Jung HU, Yoo SH, Jeong NY, Lee HJ, Suh S, Seo SY, Cheong J, Jeong JS, Yoo YH.

J Hepatol. 2015 Aug;63(2):477-85. doi: 10.1016/j.jhep.2015.01.025. Epub 2015 Jan 31.

PMID:
25646886
18.

Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis.

Afonso MB, Rodrigues PM, Carvalho T, Caridade M, Borralho P, Cortez-Pinto H, Castro RE, Rodrigues CM.

Clin Sci (Lond). 2015 Oct 1;129(8):721-39. doi: 10.1042/CS20140732. Epub 2015 Jun 15.

PMID:
26201023
19.

Ping-tang Recipe () improves insulin resistance and attenuates hepatic steatosis in high-fat diet-induced obese rats.

Yang SY, Zhao NJ, Li XJ, Zhang HJ, Chen KJ, Li CD.

Chin J Integr Med. 2012 Apr;18(4):262-8. doi: 10.1007/s11655-012-1023-0. Epub 2012 Mar 30.

PMID:
22457136
20.

Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice.

Hsu WH, Chen TH, Lee BH, Hsu YW, Pan TM.

Food Chem Toxicol. 2014 Feb;64:94-103. doi: 10.1016/j.fct.2013.11.015. Epub 2013 Nov 22.

PMID:
24275089
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