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Results: 1 to 20 of 102

1.

IRF4 is a key thermogenic transcriptional partner of PGC-1α.

Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen ED.

Cell. 2014 Jul 3;158(1):69-83. doi: 10.1016/j.cell.2014.04.049.

PMID:
24995979
[PubMed - indexed for MEDLINE]
2.

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation.

Uldry M, Yang W, St-Pierre J, Lin J, Seale P, Spiegelman BM.

Cell Metab. 2006 May;3(5):333-41.

PMID:
16679291
[PubMed - indexed for MEDLINE]
Free Article
3.

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes.

Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessì-Fulgheri P, Zhang C, Takahashi N, Sarzani R, Collins S.

J Clin Invest. 2012 Mar 1;122(3):1022-36. doi: 10.1172/JCI59701. Epub 2012 Feb 6. Erratum in: J Clin Invest. 2012 Apr 2;122(4):1584.

PMID:
22307324
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, Villarroya F, Giralt M.

J Biol Chem. 2011 Dec 16;286(50):43112-22. doi: 10.1074/jbc.M111.252775. Epub 2011 Oct 27.

PMID:
22033933
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

NT-PGC-1α protein is sufficient to link β3-adrenergic receptor activation to transcriptional and physiological components of adaptive thermogenesis.

Chang JS, Fernand V, Zhang Y, Shin J, Jun HJ, Joshi Y, Gettys TW.

J Biol Chem. 2012 Mar 16;287(12):9100-11. doi: 10.1074/jbc.M111.320200. Epub 2012 Jan 26.

PMID:
22282499
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes.

Karamitri A, Shore AM, Docherty K, Speakman JR, Lomax MA.

J Biol Chem. 2009 Jul 31;284(31):20738-52. doi: 10.1074/jbc.M109.021766. Epub 2009 Jun 2.

PMID:
19491401
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Acquirement of brown fat cell features by human white adipocytes.

Tiraby C, Tavernier G, Lefort C, Larrouy D, Bouillaud F, Ricquier D, Langin D.

J Biol Chem. 2003 Aug 29;278(35):33370-6. Epub 2003 Jun 13.

PMID:
12807871
[PubMed - indexed for MEDLINE]
Free Article
8.

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes.

Shi T, Wang F, Stieren E, Tong Q.

J Biol Chem. 2005 Apr 8;280(14):13560-7. Epub 2005 Jan 14.

PMID:
15653680
[PubMed - indexed for MEDLINE]
Free Article
9.

p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene.

Cao W, Daniel KW, Robidoux J, Puigserver P, Medvedev AV, Bai X, Floering LM, Spiegelman BM, Collins S.

Mol Cell Biol. 2004 Apr;24(7):3057-67.

PMID:
15024092
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Defective thermoregulation, impaired lipid metabolism, but preserved adrenergic induction of gene expression in brown fat of mice lacking C/EBPbeta.

Carmona MC, Hondares E, Rodríguez de la Concepción ML, Rodríguez-Sureda V, Peinado-Onsurbe J, Poli V, Iglesias R, Villarroya F, Giralt M.

Biochem J. 2005 Jul 1;389(Pt 1):47-56.

PMID:
15762841
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic variation in brown fat activity and body weight regulation in mice: lessons for human studies.

Kozak LP.

Biochim Biophys Acta. 2014 Mar;1842(3):370-6. doi: 10.1016/j.bbadis.2013.04.025. Epub 2013 May 2. Review.

PMID:
23644163
[PubMed - indexed for MEDLINE]
12.

Sequestration of thermogenic transcription factors in the cytoplasm during development of brown adipose tissue.

Rim JS, Xue B, Gawronska-Kozak B, Kozak LP.

J Biol Chem. 2004 Jun 11;279(24):25916-26. Epub 2004 Apr 8.

PMID:
15073176
[PubMed - indexed for MEDLINE]
Free Article
13.

White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis.

Cao L, Choi EY, Liu X, Martin A, Wang C, Xu X, During MJ.

Cell Metab. 2011 Sep 7;14(3):324-38. doi: 10.1016/j.cmet.2011.06.020.

PMID:
21907139
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Dietary fat interacts with QTLs controlling induction of Pgc-1 alpha and Ucp1 during conversion of white to brown fat.

Coulter AA, Bearden CM, Liu X, Koza RA, Kozak LP.

Physiol Genomics. 2003 Jul 7;14(2):139-47.

PMID:
12746468
[PubMed - indexed for MEDLINE]
15.

Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesis.

Matthias A, Ohlson KB, Fredriksson JM, Jacobsson A, Nedergaard J, Cannon B.

J Biol Chem. 2000 Aug 18;275(33):25073-81.

PMID:
10825155
[PubMed - indexed for MEDLINE]
Free Article
16.

Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues.

Lin L, Saha PK, Ma X, Henshaw IO, Shao L, Chang BH, Buras ED, Tong Q, Chan L, McGuinness OP, Sun Y.

Aging Cell. 2011 Dec;10(6):996-1010. doi: 10.1111/j.1474-9726.2011.00740.x. Epub 2011 Oct 12.

PMID:
21895961
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The orphan nuclear receptor SHP regulates PGC-1alpha expression and energy production in brown adipocytes.

Wang L, Liu J, Saha P, Huang J, Chan L, Spiegelman B, Moore DD.

Cell Metab. 2005 Oct;2(4):227-38.

PMID:
16213225
[PubMed - indexed for MEDLINE]
Free Article
18.

Leanness of Lou/C rats does not require higher thermogenic capacity of brown adipose tissue.

Belouze M, Sibille B, Rey B, Roussel D, Romestaing C, Teulier L, Baetz D, Koubi H, Servais S, Duchamp C.

Physiol Behav. 2011 Oct 24;104(5):893-9. doi: 10.1016/j.physbeh.2011.05.029. Epub 2011 May 31.

PMID:
21658398
[PubMed - indexed for MEDLINE]
19.

UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic.

Shabalina IG, Petrovic N, de Jong JM, Kalinovich AV, Cannon B, Nedergaard J.

Cell Rep. 2013 Dec 12;5(5):1196-203. doi: 10.1016/j.celrep.2013.10.044. Epub 2013 Nov 27.

PMID:
24290753
[PubMed - indexed for MEDLINE]
Free Article
20.

Peroxisome proliferator-activated receptor-gamma coactivator-1alpha controls transcription of the Sirt3 gene, an essential component of the thermogenic brown adipocyte phenotype.

Giralt A, Hondares E, Villena JA, Ribas F, Díaz-Delfín J, Giralt M, Iglesias R, Villarroya F.

J Biol Chem. 2011 May 13;286(19):16958-66. doi: 10.1074/jbc.M110.202390. Epub 2011 Mar 27.

PMID:
21454513
[PubMed - indexed for MEDLINE]
Free PMC Article

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