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Results: 1 to 20 of 102

1.

Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia.

Dandekar S, Romanos-Sirakis E, Pais F, Bhatla T, Jones C, Bourgeois W, Hunger SP, Raetz EA, Hermiston ML, Dasgupta R, Morrison DJ, Carroll WL.

Br J Haematol. 2014 Oct;167(1):87-99. doi: 10.1111/bjh.13011. Epub 2014 Jul 4.

PMID:
24995804
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Activation of Wnt/beta-catenin pathway mediates growth and survival in B-cell progenitor acute lymphoblastic leukaemia.

Khan NI, Bradstock KF, Bendall LJ.

Br J Haematol. 2007 Aug;138(3):338-48.

PMID:
17614820
[PubMed - indexed for MEDLINE]
3.

Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.

Gang EJ, Hsieh YT, Pham J, Zhao Y, Nguyen C, Huantes S, Park E, Naing K, Klemm L, Swaminathan S, Conway EM, Pelus LM, Crispino J, Mullighan CG, McMillan M, Müschen M, Kahn M, Kim YM.

Oncogene. 2014 Apr 24;33(17):2169-78. doi: 10.1038/onc.2013.169. Epub 2013 Jun 3.

PMID:
23728349
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evidence of a role for activation of Wnt/beta-catenin signaling in the resistance of plasma cells to lenalidomide.

Bjorklund CC, Ma W, Wang ZQ, Davis RE, Kuhn DJ, Kornblau SM, Wang M, Shah JJ, Orlowski RZ.

J Biol Chem. 2011 Apr 1;286(13):11009-20. doi: 10.1074/jbc.M110.180208. Epub 2010 Dec 28.

PMID:
21189262
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia.

Román-Gómez J, Cordeu L, Agirre X, Jiménez-Velasco A, San José-Eneriz E, Garate L, Calasanz MJ, Heiniger A, Torres A, Prosper F.

Blood. 2007 Apr 15;109(8):3462-9. Epub 2006 Dec 5. Retraction in: Blood. 2012 Oct 25;120(17):3625.

PMID:
17148581
[PubMed - indexed for MEDLINE]
Free Article
6.

The Wnt receptor FZD1 mediates chemoresistance in neuroblastoma through activation of the Wnt/beta-catenin pathway.

Flahaut M, Meier R, Coulon A, Nardou KA, Niggli FK, Martinet D, Beckmann JS, Joseph JM, Mühlethaler-Mottet A, Gross N.

Oncogene. 2009 Jun 11;28(23):2245-56. doi: 10.1038/onc.2009.80. Epub 2009 May 4.

PMID:
19421142
[PubMed - indexed for MEDLINE]
7.

The epigenetically regulated effects of Wnt antagonists on the expression of genes in the apoptosis pathway in human bladder cancer cell line (T24).

Varol N, Konac E, Onen IH, Gurocak S, Alp E, Yilmaz A, Menevse S, Sozen S.

DNA Cell Biol. 2014 Jul;33(7):408-17. doi: 10.1089/dna.2013.2285. Epub 2014 Mar 25.

PMID:
24665856
[PubMed - indexed for MEDLINE]
8.

Regulation of Wnt signaling activity for growth suppression induced by quercetin in 4T1 murine mammary cancer cells.

Kim H, Seo EM, Sharma AR, Ganbold B, Park J, Sharma G, Kang YH, Song DK, Lee SS, Nam JS.

Int J Oncol. 2013 Oct;43(4):1319-25. doi: 10.3892/ijo.2013.2036. Epub 2013 Jul 23.

PMID:
23900432
[PubMed - indexed for MEDLINE]
9.

The Wnt signaling pathway regulates Nalm-16 b-cell precursor acute lymphoblastic leukemic cell line survival and etoposide resistance.

Thiago LS, Costa ES, Lopes DV, Otazu IB, Nowill AE, Mendes FA, Portilho DM, Abreu JG, Mermelstein CS, Orfao A, Rossi MI, Borojevic R.

Biomed Pharmacother. 2010 Jan;64(1):63-72. doi: 10.1016/j.biopha.2009.09.005. Epub 2009 Oct 27.

PMID:
19864107
[PubMed - indexed for MEDLINE]
10.

Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65--a novel Wnt/β-catenin signaling inhibitor.

Nagao R, Ashihara E, Kimura S, Strovel JW, Yao H, Takeuchi M, Tanaka R, Hayashi Y, Hirai H, Padia J, Strand K, Maekawa T.

Cancer Lett. 2011 Dec 15;312(1):91-100. doi: 10.1016/j.canlet.2011.08.002. Epub 2011 Aug 17.

PMID:
21906872
[PubMed - indexed for MEDLINE]
11.

Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia.

Shao N, Zou J, Li J, Chen F, Dai J, Qu X, Sun X, Ma D, Ji C.

Leuk Lymphoma. 2012 Sep;53(9):1769-78. doi: 10.3109/10428194.2012.663085. Epub 2012 Mar 13.

PMID:
22303878
[PubMed - indexed for MEDLINE]
12.

Influence of five potential anticancer drugs on wnt pathway and cell survival in human biliary tract cancer cells.

Wachter J, Neureiter D, Alinger B, Pichler M, Fuereder J, Oberdanner C, Di Fazio P, Ocker M, Berr F, Kiesslich T.

Int J Biol Sci. 2012;8(1):15-29. Epub 2011 Nov 7.

PMID:
22211101
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeted inhibition of T-cell factor activity promotes syndecan-2 expression and sensitization to doxorubicin in osteosarcoma cells and bone tumors in mice.

Dieudonné FX, Marion A, Marie PJ, Modrowski D.

J Bone Miner Res. 2012 Oct;27(10):2118-29. doi: 10.1002/jbmr.1650.

PMID:
22550000
[PubMed - indexed for MEDLINE]
14.

Role of Wnt/β-catenin signaling in drug resistance of pancreatic cancer.

Cui J, Jiang W, Wang S, Wang L, Xie K.

Curr Pharm Des. 2012;18(17):2464-71. Review.

PMID:
22372504
[PubMed - indexed for MEDLINE]
15.

c-Kit mediates chemoresistance and tumor-initiating capacity of ovarian cancer cells through activation of Wnt/β-catenin-ATP-binding cassette G2 signaling.

Chau WK, Ip CK, Mak AS, Lai HC, Wong AS.

Oncogene. 2013 May 30;32(22):2767-81. doi: 10.1038/onc.2012.290. Epub 2012 Jul 16.

PMID:
22797058
[PubMed - indexed for MEDLINE]
16.

Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.

Sengupta TK, Leclerc GM, Hsieh-Kinser TT, Leclerc GJ, Singh I, Barredo JC.

Mol Cancer. 2007 Jul 10;6:46.

PMID:
17623090
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The gene expression signature of relapse in paediatric acute lymphoblastic leukaemia: implications for mechanisms of therapy failure.

Beesley AH, Cummings AJ, Freitas JR, Hoffmann K, Firth MJ, Ford J, de Klerk NH, Kees UR.

Br J Haematol. 2005 Nov;131(4):447-56.

PMID:
16281934
[PubMed - indexed for MEDLINE]
18.

Wnt pathway activity confers chemoresistance to cancer stem-like cells in a neuroblastoma cell line.

Vangipuram SD, Buck SA, Lyman WD.

Tumour Biol. 2012 Dec;33(6):2173-83. doi: 10.1007/s13277-012-0478-0. Epub 2012 Aug 11.

PMID:
22886526
[PubMed - indexed for MEDLINE]
19.

Building better therapy for children with acute lymphoblastic leukemia.

Carroll WL, Raetz EA.

Cancer Cell. 2005 Apr;7(4):289-91.

PMID:
15837616
[PubMed - indexed for MEDLINE]
Free Article
20.

Alternative signaling pathways as potential therapeutic targets for overcoming EGFR and c-Met inhibitor resistance in non-small cell lung cancer.

Fong JT, Jacobs RJ, Moravec DN, Uppada SB, Botting GM, Nlend M, Puri N.

PLoS One. 2013 Nov 4;8(11):e78398. doi: 10.1371/journal.pone.0078398. eCollection 2013.

PMID:
24223799
[PubMed - indexed for MEDLINE]
Free PMC Article

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