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Results: 1 to 20 of 102

1.

Factor VIIa binding to endothelial cell protein C receptor protects vascular barrier integrity in vivo.

Sundaram J, Keshava S, Gopalakrishnan R, Esmon CT, Pendurthi UR, Rao LV.

J Thromb Haemost. 2014 May;12(5):690-700.

PMID:
24977291
[PubMed - indexed for MEDLINE]
2.

Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection.

Sen P, Gopalakrishnan R, Kothari H, Keshava S, Clark CA, Esmon CT, Pendurthi UR, Rao LV.

Blood. 2011 Mar 17;117(11):3199-208. doi: 10.1182/blood-2010-09-310706. Epub 2011 Jan 20.

PMID:
21252088
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa.

Clark CA, Vatsyayan R, Hedner U, Esmon CT, Pendurthi UR, Rao LV.

J Thromb Haemost. 2012 Nov;10(11):2383-91. doi: 10.1111/j.1538-7836.2012.04917.x.

PMID:
22950420
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Factor VIIa binding to endothelial cell protein C receptor: differences between mouse and human systems.

Sen P, Clark CA, Gopalakrishnan R, Hedner U, Esmon CT, Pendurthi UR, Rao LV.

Thromb Haemost. 2012 May;107(5):951-61. doi: 10.1160/TH11-09-0672. Epub 2012 Feb 28.

PMID:
22370814
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium.

Ghosh S, Pendurthi UR, Steinoe A, Esmon CT, Rao LV.

J Biol Chem. 2007 Apr 20;282(16):11849-57. Epub 2007 Feb 27.

PMID:
17327234
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Factor VIIa binding to endothelial cell protein C receptor.

Rao LV, Pendurthi UR.

Thromb Res. 2008;122 Suppl 1:S3-6. doi: 10.1016/S0049-3848(08)70009-4. Review.

PMID:
18691496
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors.

Disse J, Petersen HH, Larsen KS, Persson E, Esmon N, Esmon CT, Teyton L, Petersen LC, Ruf W.

J Biol Chem. 2011 Feb 18;286(7):5756-67. doi: 10.1074/jbc.M110.201228. Epub 2010 Dec 13.

PMID:
21149441
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Endothelial cell protein C receptor cellular localization and trafficking: potential functional implications.

Nayak RC, Sen P, Ghosh S, Gopalakrishnan R, Esmon CT, Pendurthi UR, Rao LV.

Blood. 2009 Aug 27;114(9):1974-86. doi: 10.1182/blood-2009-03-208900. Epub 2009 Jul 8.

PMID:
19587380
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Binding of factor VIIa to the endothelial cell protein C receptor reduces its coagulant activity.

López-Sagaseta J, Montes R, Puy C, Díez N, Fukudome K, Hermida J.

J Thromb Haemost. 2007 Sep;5(9):1817-24.

PMID:
17723119
[PubMed - indexed for MEDLINE]
10.

Vascular endothelial growth factor production by fibroblasts in response to factor VIIa binding to tissue factor involves thrombin and factor Xa.

Ollivier V, Chabbat J, Herbert JM, Hakim J, de Prost D.

Arterioscler Thromb Vasc Biol. 2000 May;20(5):1374-81.

PMID:
10807756
[PubMed - indexed for MEDLINE]
Free Article
11.

Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.

Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG.

J Biol Chem. 2005 Apr 29;280(17):17286-93. Epub 2005 Feb 14.

PMID:
15710622
[PubMed - indexed for MEDLINE]
Free Article
12.

Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor.

Pendurthi UR, Rao LV.

Thromb Res. 2010 Apr;125 Suppl 1:S19-22. doi: 10.1016/j.thromres.2010.01.026. Epub 2010 Feb 14. Review.

PMID:
20156643
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Coagulation factor Xa cleaves protease-activated receptor-1 and mediates signaling dependent on binding to the endothelial protein C receptor.

Schuepbach RA, Riewald M.

J Thromb Haemost. 2010 Feb;8(2):379-88. doi: 10.1111/j.1538-7836.2009.03682.x. Epub 2009 Nov 6.

PMID:
19895674
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

Factor X/Xa elicits protective signaling responses in endothelial cells directly via PAR-2 and indirectly via endothelial protein C receptor-dependent recruitment of PAR-1.

Bae JS, Yang L, Rezaie AR.

J Biol Chem. 2010 Nov 5;285(45):34803-12. doi: 10.1074/jbc.M110.163642. Epub 2010 Sep 8.

PMID:
20826780
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1.

Schuepbach RA, Feistritzer C, Fernández JA, Griffin JH, Riewald M.

Thromb Haemost. 2009 Apr;101(4):724-33.

PMID:
19350118
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The endothelial cells downregulate the generation of factor VIIa through EPCR binding.

Puy C, López-Sagaseta J, Hermida J, Montes R.

Br J Haematol. 2010 Apr;149(1):111-7. doi: 10.1111/j.1365-2141.2009.08060.x. Epub 2010 Jan 18.

PMID:
20085578
[PubMed - indexed for MEDLINE]
18.

Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa.

Nayak RC, Keshava S, Esmon CT, Pendurthi UR, Rao LV.

PLoS One. 2013;8(3):e59304. doi: 10.1371/journal.pone.0059304. Epub 2013 Mar 15.

PMID:
23555015
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice.

Lagrange J, Li Z, Fassot C, Bourhim M, Louis H, Nguyen Dinh Cat A, Parlakian A, Wahl D, Lacolley P, Jaisser F, Regnault V.

FASEB J. 2014 May;28(5):2062-72. doi: 10.1096/fj.13-238188. Epub 2014 Jan 22.

PMID:
24451386
[PubMed - indexed for MEDLINE]
20.

Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.

Li W, Zheng X, Gu J, Hunter J, Ferrell GL, Lupu F, Esmon NL, Esmon CT.

J Thromb Haemost. 2005 Jul;3(7):1351-9.

PMID:
15978090
[PubMed - indexed for MEDLINE]
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