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Results: 1 to 20 of 101

1.

Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers.

Abdel-Fatah T, Arora A, Agarwal D, Moseley P, Perry C, Thompson N, Green AR, Rakha E, Chan S, Ball G, Ellis IO, Madhusudan S.

Breast Cancer Res Treat. 2014 Jul;146(2):309-20. doi: 10.1007/s10549-014-3035-2. Epub 2014 Jun 28.

PMID:
24972688
[PubMed - in process]
2.

Clinicopathological significance of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in oestrogen-receptor-positive breast cancer.

Abdel-Fatah TM, Perry C, Moseley P, Johnson K, Arora A, Chan S, Ellis IO, Madhusudan S.

Breast Cancer Res Treat. 2014 Feb;143(3):411-21. doi: 10.1007/s10549-013-2820-7. Epub 2014 Jan 1.

PMID:
24381055
[PubMed - indexed for MEDLINE]
3.

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.

Abdel-Fatah TM, Albarakati N, Bowell L, Agarwal D, Moseley P, Hawkes C, Ball G, Chan S, Ellis IO, Madhusudan S.

Breast Cancer Res Treat. 2013 Dec;142(3):515-27. doi: 10.1007/s10549-013-2769-6. Epub 2013 Nov 20.

PMID:
24253812
[PubMed - indexed for MEDLINE]
4.

Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.

Albarakati N, Abdel-Fatah TM, Doherty R, Russell R, Agarwal D, Moseley P, Perry C, Arora A, Alsubhi N, Seedhouse C, Rakha EA, Green A, Ball G, Chan S, Caldas C, Ellis IO, Madhusudan S.

Mol Oncol. 2014 Aug 27. pii: S1574-7891(14)00183-5. doi: 10.1016/j.molonc.2014.08.001. [Epub ahead of print]

PMID:
25205036
[PubMed - as supplied by publisher]
5.

Expression of DNA-PKcs and BRCA1 as prognostic indicators in nasopharyngeal carcinoma following intensity-modulated radiation therapy.

Yang J, Xu X, Hao Y, Chen J, Lu H, Qin J, Peng L, Chen B.

Oncol Lett. 2013 Apr;5(4):1199-1204. Epub 2013 Feb 18.

PMID:
23599763
[PubMed]
Free PMC Article
6.

Is there a role for base excision repair in estrogen/estrogen receptor-driven breast cancers?

Abdel-Fatah TM, Perry C, Arora A, Thompson N, Doherty R, Moseley PM, Green AR, Chan SY, Ellis IO, Madhusudan S.

Antioxid Redox Signal. 2014 Dec 1;21(16):2262-8. doi: 10.1089/ars.2014.6077. Epub 2014 Sep 22.

PMID:
25111287
[PubMed - in process]
7.
8.

Nuclear survivin and its relationship to DNA damage repair genes in non-small cell lung cancer investigated using tissue array.

Hu S, Qu Y, Xu X, Xu Q, Geng J, Xu J.

PLoS One. 2013 Sep 16;8(9):e74161. doi: 10.1371/journal.pone.0074161. eCollection 2013. Erratum in: PLoS One. 2013;8(12). doi:10.1371/annotation/a87d46d5-04ee-4c57-af2b-7b9af5166cd8.

PMID:
24066112
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.

Abdel-Fatah TM, Russell R, Albarakati N, Maloney DJ, Dorjsuren D, Rueda OM, Moseley P, Mohan V, Sun H, Abbotts R, Mukherjee A, Agarwal D, Illuzzi JL, Jadhav A, Simeonov A, Ball G, Chan S, Caldas C, Ellis IO, Wilson DM 3rd, Madhusudan S.

Mol Oncol. 2014 Oct;8(7):1326-38. doi: 10.1016/j.molonc.2014.04.009. Epub 2014 May 13.

PMID:
24880630
[PubMed - in process]
10.

The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.

Treilleux I, Chapot B, Goddard S, Pisani P, Angèle S, Hall J.

Histopathology. 2007 Jul;51(1):63-9.

PMID:
17593081
[PubMed - indexed for MEDLINE]
11.

Low expression of Ku70/80, but high expression of DNA-PKcs, predict good response to radiotherapy in early breast cancer.

Söderlund Leifler K, Queseth S, Fornander T, Askmalm MS.

Int J Oncol. 2010 Dec;37(6):1547-54.

PMID:
21042724
[PubMed - indexed for MEDLINE]
12.

DNA-PKcs expression predicts response to radiotherapy in prostate cancer.

Bouchaert P, Guerif S, Debiais C, Irani J, Fromont G.

Int J Radiat Oncol Biol Phys. 2012 Dec 1;84(5):1179-85. doi: 10.1016/j.ijrobp.2012.02.014. Epub 2012 Apr 9.

PMID:
22494583
[PubMed - indexed for MEDLINE]
13.

Altered expression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) during gastric carcinogenesis and its clinical implications on gastric cancer.

Lee HS, Choe G, Park KU, Park do J, Yang HK, Lee BL, Kim WH.

Int J Oncol. 2007 Oct;31(4):859-66.

PMID:
17786318
[PubMed - indexed for MEDLINE]
14.

p53-deficient cells display increased sensitivity to anthracyclines after loss of the catalytic subunit of the DNA-dependent protein kinase.

Fedier A, Moawad A, Haller U, Fink D.

Int J Oncol. 2003 Nov;23(5):1431-7.

PMID:
14532987
[PubMed - indexed for MEDLINE]
15.

Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment.

Hsu FM, Zhang S, Chen BP.

Transl Cancer Res. 2012 Jun 1;1(1):22-34. Epub 2012 May 22.

PMID:
22943041
[PubMed]
Free PMC Article
16.

Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.

Shang ZF, Huang B, Xu QZ, Zhang SM, Fan R, Liu XD, Wang Y, Zhou PK.

Cancer Res. 2010 May 1;70(9):3657-66. doi: 10.1158/0008-5472.CAN-09-3362. Epub 2010 Apr 20.

PMID:
20406977
[PubMed - indexed for MEDLINE]
Free Article
17.

Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.

Peng Y, Woods RG, Beamish H, Ye R, Lees-Miller SP, Lavin MF, Bedford JS.

Cancer Res. 2005 Mar 1;65(5):1670-7.

PMID:
15753361
[PubMed - indexed for MEDLINE]
Free Article
18.

Inactivation of DNA-dependent protein kinase promotes heat-induced apoptosis independently of heat-shock protein induction in human cancer cell lines.

Okazawa S, Furusawa Y, Kariya A, Hassan MA, Arai M, Hayashi R, Tabuchi Y, Kondo T, Tobe K.

PLoS One. 2013;8(3):e58325. doi: 10.1371/journal.pone.0058325. Epub 2013 Mar 11.

PMID:
23505488
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends.

Block WD, Yu Y, Merkle D, Gifford JL, Ding Q, Meek K, Lees-Miller SP.

Nucleic Acids Res. 2004 Aug 16;32(14):4351-7. Print 2004.

PMID:
15314205
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells.

An J, Xu QZ, Sui JL, Bai B, Zhou PK.

Int J Cancer. 2005 Nov 20;117(4):531-7.

PMID:
15929110
[PubMed - indexed for MEDLINE]

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