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Items: 1 to 20 of 206

1.

p38 MAPK signaling mediates mitochondrial apoptosis in cancer cells induced by oleanolic acid.

Liu J, Wu N, Ma LN, Zhong JT, Liu G, Zheng LH, Lin XK.

Asian Pac J Cancer Prev. 2014;15(11):4519-25.

2.

Triggering of p38 MAPK and JNK signaling is important for oleanolic acid-induced apoptosis via the mitochondrial death pathway in hypertrophic scar fibroblasts.

Chen JY, Zhang L, Zhang H, Su L, Qin LP.

Phytother Res. 2014 Oct;28(10):1468-78. doi: 10.1002/ptr.5150. Epub 2014 Apr 6.

PMID:
24706573
3.

Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.

Ravindran J, Gupta N, Agrawal M, Bala Bhaskar AS, Lakshmana Rao PV.

Apoptosis. 2011 Feb;16(2):145-61. doi: 10.1007/s10495-010-0554-0.

PMID:
21082355
4.

Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.

Chang KC, Hsu CC, Liu SH, Su CC, Yen CC, Lee MJ, Chen KL, Ho TJ, Hung DZ, Wu CC, Lu TH, Su YC, Chen YW, Huang CF.

PLoS One. 2013;8(2):e54374. doi: 10.1371/journal.pone.0054374. Epub 2013 Feb 6.

5.

MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells.

Yuan L, Wang J, Xiao H, Wu W, Wang Y, Liu X.

Food Chem Toxicol. 2013 Mar;53:62-8. doi: 10.1016/j.fct.2012.11.048. Epub 2012 Dec 5.

PMID:
23220614
6.

Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.

Hsu WH, Hsieh YS, Kuo HC, Teng CY, Huang HI, Wang CJ, Yang SF, Liou YS, Kuo WH.

Arch Toxicol. 2007 Oct;81(10):719-28. Epub 2007 Aug 3.

PMID:
17673978
7.

Reactive oxygen species-mediated mitochondrial pathway is involved in Baohuoside I-induced apoptosis in human non-small cell lung cancer.

Song J, Shu L, Zhang Z, Tan X, Sun E, Jin X, Chen Y, Jia X.

Chem Biol Interact. 2012 Jul 30;199(1):9-17. doi: 10.1016/j.cbi.2012.05.005. Epub 2012 Jun 9.

PMID:
22687635
8.

Involvement of p38 MAPK- and JNK-modulated expression of Bcl-2 and Bax in Naja nigricollis CMS-9-induced apoptosis of human leukemia K562 cells.

Chen YJ, Liu WH, Kao PH, Wang JJ, Chang LS.

Toxicon. 2010 Jun 15;55(7):1306-16. doi: 10.1016/j.toxicon.2010.01.024. Epub 2010 Feb 6.

PMID:
20144638
9.

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.

Kang YH, Lee SJ.

J Cell Physiol. 2008 Oct;217(1):23-33. doi: 10.1002/jcp.21470.

PMID:
18412143
10.

A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.

Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):659-71. doi: 10.1016/j.taap.2013.10.015. Epub 2013 Oct 22.

PMID:
24161344
11.

Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.

Wang X, Bai H, Zhang X, Liu J, Cao P, Liao N, Zhang W, Wang Z, Hai C.

Carcinogenesis. 2013 Jun;34(6):1323-30. doi: 10.1093/carcin/bgt058. Epub 2013 Feb 12.

12.

Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.

Seo SK, Lee HC, Woo SH, Jin HO, Yoo DH, Lee SJ, An S, Choe TB, Park MJ, Hong SI, Park IC, Rhee CH.

Apoptosis. 2007 Jan;12(1):195-209.

PMID:
17136320
13.

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

Park MT, Choi JA, Kim MJ, Um HD, Bae S, Kang CM, Cho CK, Kang S, Chung HY, Lee YS, Lee SJ.

J Biol Chem. 2003 Dec 12;278(50):50624-34. Epub 2003 Sep 30.

14.

Mycotoxin zearalenone induces AIF- and ROS-mediated cell death through p53- and MAPK-dependent signaling pathways in RAW264.7 macrophages.

Yu JY, Zheng ZH, Son YO, Shi X, Jang YO, Lee JC.

Toxicol In Vitro. 2011 Dec;25(8):1654-63. doi: 10.1016/j.tiv.2011.07.002. Epub 2011 Jul 13.

PMID:
21767629
15.

The role of mitogen-activated protein kinase in cadmium-induced primary rat cerebral cortical neurons apoptosis via a mitochondrial apoptotic pathway.

Yuan Y, Jiang C, Hu F, Wang Q, Zhang K, Wang Y, Gu J, Liu X, Bian J, Liu Z.

J Trace Elem Med Biol. 2015 Jan;29:275-83. doi: 10.1016/j.jtemb.2014.06.006. Epub 2014 Jun 24.

PMID:
25043952
16.

NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway.

Liu L, Fu J, Li T, Cui R, Ling J, Yu X, Ji H, Zhang Y.

Eur J Pharmacol. 2012 Sep 15;691(1-3):61-8. doi: 10.1016/j.ejphar.2012.07.031. Epub 2012 Jul 20.

PMID:
22824464
17.

Chicoric acid induces apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways.

Xiao H, Wang J, Yuan L, Xiao C, Wang Y, Liu X.

J Agric Food Chem. 2013 Feb 20;61(7):1509-20. doi: 10.1021/jf3050268. Epub 2013 Feb 11.

PMID:
23363008
18.
19.
20.

ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death.

Sarker KP, Biswas KK, Yamakuchi M, Lee KY, Hahiguchi T, Kracht M, Kitajima I, Maruyama I.

J Neurochem. 2003 Apr;85(1):50-61.

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