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Results: 1 to 20 of 105

Similar articles for PubMed (Select 24967846)

1.

Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteins.

DeBartolo J, Taipale M, Keating AE.

PLoS Comput Biol. 2014 Jun 26;10(6):e1003693. doi: 10.1371/journal.pcbi.1003693. eCollection 2014 Jun.

2.

Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL.

Dutta S, Gullá S, Chen TS, Fire E, Grant RA, Keating AE.

J Mol Biol. 2010 May 21;398(5):747-62. doi: 10.1016/j.jmb.2010.03.058. Epub 2010 Apr 2.

3.

Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent.

Modi V, Lama D, Sankararamakrishnan R.

J Biomol Struct Dyn. 2013;31(1):65-77. doi: 10.1080/07391102.2012.691363. Epub 2012 Jul 18.

PMID:
22803956
4.

Peptide ligands for pro-survival protein Bfl-1 from computationally guided library screening.

Dutta S, Chen TS, Keating AE.

ACS Chem Biol. 2013 Apr 19;8(4):778-88. doi: 10.1021/cb300679a. Epub 2013 Feb 21.

5.

Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins.

Foight GW, Keating AE.

J Mol Biol. 2015 May 23. pii: S0022-2836(15)00299-5. doi: 10.1016/j.jmb.2015.05.015. [Epub ahead of print]

PMID:
26009469
6.

Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L).

Lama D, Sankararamakrishnan R.

J Comput Aided Mol Des. 2011 May;25(5):413-26. doi: 10.1007/s10822-011-9428-y. Epub 2011 Apr 27.

PMID:
21523491
7.

Potent and specific peptide inhibitors of human pro-survival protein Bcl-xL.

Dutta S, Ryan J, Chen TS, Kougentakis C, Letai A, Keating AE.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1241-53. doi: 10.1016/j.jmb.2014.09.030. Epub 2014 Nov 14.

PMID:
25451027
8.

Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins.

Lee EF, Fedorova A, Zobel K, Boyle MJ, Yang H, Perugini MA, Colman PM, Huang DC, Deshayes K, Fairlie WD.

J Biol Chem. 2009 Nov 6;284(45):31315-26. doi: 10.1074/jbc.M109.048009. Epub 2009 Sep 10.

9.

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.

Day CL, Chen L, Richardson SJ, Harrison PJ, Huang DC, Hinds MG.

J Biol Chem. 2005 Feb 11;280(6):4738-44. Epub 2004 Nov 18.

10.
11.

In silico and in vitro elucidation of BH3 binding specificity toward Bcl-2.

London N, Gullá S, Keating AE, Schueler-Furman O.

Biochemistry. 2012 Jul 24;51(29):5841-50. doi: 10.1021/bi3003567. Epub 2012 Jul 12.

12.

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.

Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC.

Mol Cell. 2005 Feb 4;17(3):393-403.

PMID:
15694340
13.

Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death.

Inohara N, Gourley TS, Carrio R, Muñiz M, Merino J, Garcia I, Koseki T, Hu Y, Chen S, Núñez G.

J Biol Chem. 1998 Dec 4;273(49):32479-86.

14.
15.

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions.

Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH.

J Am Chem Soc. 2007 Jan 10;129(1):139-54.

PMID:
17199293
16.

Structural biology of the Bcl-2 family of proteins.

Petros AM, Olejniczak ET, Fesik SW.

Biochim Biophys Acta. 2004 Mar 1;1644(2-3):83-94. Review.

PMID:
14996493
17.

Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.

Lee MS, Ha JH, Yoon HS, Lee CK, Chi SW.

Biochem Biophys Res Commun. 2014 Feb 28;445(1):120-5. doi: 10.1016/j.bbrc.2014.01.130. Epub 2014 Feb 1.

PMID:
24491548
18.

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.

Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM.

J Cell Biol. 2007 Apr 23;177(2):277-87.

19.

Antiapoptotic Bcl-2 homolog CED-9 in Caenorhabditis elegans: dynamics of BH3 and CED-4 binding regions and comparison with mammalian antiapoptotic Bcl-2 proteins.

Modi V, Sankararamakrishnan R.

Proteins. 2014 Jun;82(6):1035-47. doi: 10.1002/prot.24476. Epub 2013 Nov 23.

PMID:
24218065
20.

Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.

Zhang YH, Bhunia A, Wan KF, Lee MC, Chan SL, Yu VC, Mok YK.

J Mol Biol. 2006 Dec 1;364(3):536-49. Epub 2006 Sep 14.

PMID:
17011577
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