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Results: 1 to 20 of 94

1.

Persistent inflammation and T cell exhaustion in severe sepsis in the elderly.

Inoue S, Suzuki K, Komori Y, Morishita Y, Suzuki-Utsunomiya K, Hozumi K, Inokuchi S, Sato T.

Crit Care. 2014 Jun 24;18(3):R130. doi: 10.1186/cc13941.

PMID:
24962182
[PubMed - in process]
2.

Neutralization of interleukin-10 or transforming growth factor-β decreases the percentages of CD4+ CD25+ Foxp3+ regulatory T cells in septic mice, thereby leading to an improved survival.

Hiraki S, Ono S, Tsujimoto H, Kinoshita M, Takahata R, Miyazaki H, Saitoh D, Hase K.

Surgery. 2012 Feb;151(2):313-22. doi: 10.1016/j.surg.2011.07.019. Epub 2011 Oct 6.

PMID:
21982068
[PubMed - indexed for MEDLINE]
3.

Major injury induces increased production of interleukin-10 by cells of the immune system with a negative impact on resistance to infection.

Lyons A, Kelly JL, Rodrick ML, Mannick JA, Lederer JA.

Ann Surg. 1997 Oct;226(4):450-8; discussion 458-60.

PMID:
9351713
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Removal of increased circulating CD4+CD25+Foxp3+ regulatory T cells in patients with septic shock using hemoperfusion with polymyxin B-immobilized fibers.

Ono S, Kimura A, Hiraki S, Takahata R, Tsujimoto H, Kinoshita M, Miyazaki H, Yamamoto J, Hase K, Saitoh D.

Surgery. 2013 Feb;153(2):262-71. doi: 10.1016/j.surg.2012.06.023. Epub 2012 Aug 9.

PMID:
22884251
[PubMed - indexed for MEDLINE]
5.

Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly.

Inoue S, Suzuki-Utsunomiya K, Okada Y, Taira T, Iida Y, Miura N, Tsuji T, Yamagiwa T, Morita S, Chiba T, Sato T, Inokuchi S.

Crit Care Med. 2013 Mar;41(3):810-9. doi: 10.1097/CCM.0b013e318274645f.

PMID:
23328259
[PubMed - indexed for MEDLINE]
6.

Sepsis is characterized by the increases in percentages of circulating CD4+CD25+ regulatory T cells and plasma levels of soluble CD25.

Saito K, Wagatsuma T, Toyama H, Ejima Y, Hoshi K, Shibusawa M, Kato M, Kurosawa S.

Tohoku J Exp Med. 2008 Sep;216(1):61-8.

PMID:
18719339
[PubMed - indexed for MEDLINE]
Free Article
7.

Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis.

Scumpia PO, Delano MJ, Kelly KM, O'Malley KA, Efron PA, McAuliffe PF, Brusko T, Ungaro R, Barker T, Wynn JL, Atkinson MA, Reeves WH, Salzler MJ, Moldawer LL.

J Immunol. 2006 Dec 1;177(11):7943-9.

PMID:
17114466
[PubMed - indexed for MEDLINE]
Free Article
8.

Exogenous carbon monoxide attenuates inflammatory responses in the small intestine of septic mice.

Wang X, Cao J, Sun BW, Liu DD, Liang F, Gao L.

World J Gastroenterol. 2012 Oct 28;18(40):5719-28. doi: 10.3748/wjg.v18.i40.5719.

PMID:
23155312
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Rho kinase regulates induction of T-cell immune dysfunction in abdominal sepsis.

Hasan Z, Palani K, Zhang S, Lepsenyi M, Hwaiz R, Rahman M, Syk I, Jeppsson B, Thorlacius H.

Infect Immun. 2013 Jul;81(7):2499-506. doi: 10.1128/IAI.00126-13. Epub 2013 Apr 29.

PMID:
23630965
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mechanisms of mortality in early and late sepsis.

Xiao H, Siddiqui J, Remick DG.

Infect Immun. 2006 Sep;74(9):5227-35.

PMID:
16926416
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

Dendritic cells during polymicrobial sepsis rapidly mature but fail to initiate a protective Th1-type immune response.

Flohé SB, Agrawal H, Schmitz D, Gertz M, Flohé S, Schade FU.

J Leukoc Biol. 2006 Mar;79(3):473-81. Epub 2005 Dec 19.

PMID:
16365154
[PubMed - indexed for MEDLINE]
Free Article
13.

Injury induces deficient interleukin-12 production, but interleukin-12 therapy after injury restores resistance to infection.

Göebel A, Kavanagh E, Lyons A, Saporoschetz IB, Soberg C, Lederer JA, Mannick JA, Rodrick ML.

Ann Surg. 2000 Feb;231(2):253-61.

PMID:
10674618
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection.

O'Sullivan ST, Lederer JA, Horgan AF, Chin DH, Mannick JA, Rodrick ML.

Ann Surg. 1995 Oct;222(4):482-90; discussion 490-2.

PMID:
7574928
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Is circulating endotoxin the trigger for the systemic inflammatory response syndrome seen after injury?

Kelly JL, O'Sullivan C, O'Riordain M, O'Riordain D, Lyons A, Doherty J, Mannick JA, Rodrick ML.

Ann Surg. 1997 May;225(5):530-41; discussion 541-3.

PMID:
9193181
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Neutralization of IL-10 restores the downregulation of IL-18 receptor on natural killer cells and interferon-γ production in septic mice, thus leading to an improved survival.

Hiraki S, Ono S, Kinoshita M, Tsujimoto H, Takahata R, Miyazaki H, Saitoh D, Seki S, Hase K.

Shock. 2012 Feb;37(2):177-82. doi: 10.1097/SHK.0b013e31823f18ad.

PMID:
22089189
[PubMed - indexed for MEDLINE]
17.

Pretreatment with interleukin-6 small interfering RNA can improve the survival rate of polymicrobial cecal ligation and puncture mice by down regulating interleukin-6 production.

Mostafa Anower AK, Shim JA, Choi B, Sohn S.

Eur J Pharmacol. 2012 Aug 5;688(1-3):76-83. doi: 10.1016/j.ejphar.2012.05.007. Epub 2012 May 23.

PMID:
22634167
[PubMed - indexed for MEDLINE]
18.

Interleukin 10 extends the effectiveness of standard therapy during late sepsis with serum interleukin 6 levels predicting outcome.

Manley MO, O'Riordan MA, Levine AD, Latifi SQ.

Shock. 2005 Jun;23(6):521-6.

PMID:
15897804
[PubMed - indexed for MEDLINE]
19.

Increased proportion of CD4(+)CD25(+)Foxp3(+) regulatory T cells during early-stage sepsis in ICU patients.

Leng FY, Liu JL, Liu ZJ, Yin JY, Qu HP.

J Microbiol Immunol Infect. 2013 Oct;46(5):338-44. doi: 10.1016/j.jmii.2012.06.012. Epub 2012 Aug 24.

PMID:
22921804
[PubMed - indexed for MEDLINE]
20.

Serial increase of IL-12 response and human leukocyte antigen-DR expression in severe sepsis survivors.

Wu HP, Shih CC, Lin CY, Hua CC, Chuang DY.

Crit Care. 2011;15(5):R224. doi: 10.1186/cc10464. Epub 2011 Sep 22.

PMID:
21939530
[PubMed - indexed for MEDLINE]
Free PMC Article

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