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Results: 1 to 20 of 94

1.

The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B.

Zhang Y, Yang H, Guo X, Rong N, Song Y, Xu Y, Lan W, Zhang X, Liu M, Xu Y, Cao C.

Protein Cell. 2014 Jun 22. [Epub ahead of print]

PMID:
24952722
[PubMed - as supplied by publisher]
2.

The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.

Klein BJ, Piao L, Xi Y, Rincon-Arano H, Rothbart SB, Peng D, Wen H, Larson C, Zhang X, Zheng X, Cortazar MA, Peña PV, Mangan A, Bentley DL, Strahl BD, Groudine M, Li W, Shi X, Kutateladze TG.

Cell Rep. 2014 Jan 30;6(2):325-35. doi: 10.1016/j.celrep.2013.12.021. Epub 2014 Jan 9.

PMID:
24412361
[PubMed - in process]
Free Article
3.

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y.

Nature. 2007 Aug 9;448(7154):718-22.

PMID:
17687328
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.

Kristensen LH, Nielsen AL, Helgstrand C, Lees M, Cloos P, Kastrup JS, Helin K, Olsen L, Gajhede M.

FEBS J. 2012 Jun;279(11):1905-14. doi: 10.1111/j.1742-4658.2012.08567.x. Epub 2012 May 2.

PMID:
22420752
[PubMed - indexed for MEDLINE]
5.

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation.

Chignola F, Gaetani M, Rebane A, Org T, Mollica L, Zucchelli C, Spitaleri A, Mannella V, Peterson P, Musco G.

Nucleic Acids Res. 2009 May;37(9):2951-61. doi: 10.1093/nar/gkp166. Epub 2009 Mar 17.

PMID:
19293276
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation.

Kidder BL, Hu G, Zhao K.

Genome Biol. 2014 Feb 4;15(2):R32. [Epub ahead of print]

PMID:
24495580
[PubMed - as supplied by publisher]
Free PMC Article
7.

Exploring PHD fingers and H3K4me0 interactions with molecular dynamics simulations and binding free energy calculations: AIRE-PHD1, a comparative study.

Spiliotopoulos D, Spitaleri A, Musco G.

PLoS One. 2012;7(10):e46902. doi: 10.1371/journal.pone.0046902. Epub 2012 Oct 15.

PMID:
23077531
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).

Qin S, Jin L, Zhang J, Liu L, Ji P, Wu M, Wu J, Shi Y.

J Biol Chem. 2011 Oct 21;286(42):36944-55. doi: 10.1074/jbc.M111.244400. Epub 2011 Aug 31.

PMID:
21880731
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A).

Wong PP, Miranda F, Chan KV, Berlato C, Hurst HC, Scibetta AG.

Mol Cell Biol. 2012 May;32(9):1633-44. doi: 10.1128/MCB.06373-11. Epub 2012 Feb 27.

PMID:
22371483
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Extended self-renewal and accelerated reprogramming in the absence of Kdm5b.

Kidder BL, Hu G, Yu ZX, Liu C, Zhao K.

Mol Cell Biol. 2013 Dec;33(24):4793-810. doi: 10.1128/MCB.00692-13. Epub 2013 Oct 7.

PMID:
24100015
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation.

Dey BK, Stalker L, Schnerch A, Bhatia M, Taylor-Papidimitriou J, Wynder C.

Mol Cell Biol. 2008 Sep;28(17):5312-27. doi: 10.1128/MCB.00128-08. Epub 2008 Jun 30.

PMID:
18591252
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.

Bueno MT, Richard S.

Epigenetics. 2013 Nov;8(11):1162-75. doi: 10.4161/epi.26112. Epub 2013 Aug 22.

PMID:
23970103
[PubMed - in process]
13.

The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to-mesenchymal transition.

Tang M, Shen H, Jin Y, Lin T, Cai Q, Pinard MA, Biswas S, Tran Q, Li G, Shenoy AK, Tongdee E, Lin S, Gu Y, Law BK, Zhou L, McKenna R, Wu L, Lu J.

J Biol Chem. 2013 Sep 20;288(38):27680-91. doi: 10.1074/jbc.M113.482349. Epub 2013 Aug 8.

PMID:
23928305
[PubMed - indexed for MEDLINE]
14.

The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers.

Lallous N, Legrand P, McEwen AG, Ramón-Maiques S, Samama JP, Birck C.

PLoS One. 2011;6(11):e27599. doi: 10.1371/journal.pone.0027599. Epub 2011 Nov 11.

PMID:
22096602
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b.

Zhang Q, Qi S, Xu M, Yu L, Tao Y, Deng Z, Wu W, Li J, Chen Z, Wong J.

Cell Res. 2013 Feb;23(2):225-41. doi: 10.1038/cr.2012.177. Epub 2012 Dec 25.

PMID:
23266887
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y.

Cell. 2007 Mar 23;128(6):1077-88. Epub 2007 Feb 22.

PMID:
17320160
[PubMed - indexed for MEDLINE]
Free Article
17.

Crystallization and preliminary crystallographic analysis of a PHD domain of human JARID1B.

Guo X, Xu Y, Wang P, Li Z, Xu Y, Yang H.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):907-10. doi: 10.1107/S1744309111021981. Epub 2011 Jul 19.

PMID:
21821892
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway.

Hayami S, Yoshimatsu M, Veerakumarasivam A, Unoki M, Iwai Y, Tsunoda T, Field HI, Kelly JD, Neal DE, Yamaue H, Ponder BA, Nakamura Y, Hamamoto R.

Mol Cancer. 2010 Mar 13;9:59. doi: 10.1186/1476-4598-9-59.

PMID:
20226085
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.

Ali M, Yan K, Lalonde ME, Degerny C, Rothbart SB, Strahl BD, Côté J, Yang XJ, Kutateladze TG.

J Mol Biol. 2012 Dec 14;424(5):328-38. doi: 10.1016/j.jmb.2012.10.004. Epub 2012 Oct 12.

PMID:
23063713
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription.

Xie L, Pelz C, Wang W, Bashar A, Varlamova O, Shadle S, Impey S.

EMBO J. 2011 Apr 20;30(8):1473-84. doi: 10.1038/emboj.2011.91. Epub 2011 Mar 29.

PMID:
21448134
[PubMed - indexed for MEDLINE]
Free PMC Article

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