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Results: 1 to 20 of 95

1.

Asmase Regulates Autophagy and Lysosomal Membrane Permeabilization and its Inhibition Prevents Early Stage Nonalcoholic Steatohepatitis.

Fucho R, Martínez L, Baulies A, Torres S, Tarrats N, Fernandez A, Ribas V, Astudillo AM, Balsinde J, Garcia-Rovés P, Elena M, Bergheim I, Lotersztajn S, Trautwein C, Appelqvist H, Paton AW, Paton JC, Czaja MJ, Kaplowitz N, Fernandez-Checa JC, García-Ruiz C.

J Hepatol. 2014 Jun 16. pii: S0168-8278(14)00404-8. doi: 10.1016/j.jhep.2014.06.009. [Epub ahead of print]

PMID:
24946279
[PubMed - as supplied by publisher]
2.

ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.

Fernandez A, Matias N, Fucho R, Ribas V, Von Montfort C, Nuño N, Baulies A, Martinez L, Tarrats N, Mari M, Colell A, Morales A, Dubuquoy L, Mathurin P, Bataller R, Caballeria J, Elena M, Balsinde J, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC.

J Hepatol. 2013 Oct;59(4):805-13. doi: 10.1016/j.jhep.2013.05.023. Epub 2013 May 23.

PMID:
23707365
[PubMed - indexed for MEDLINE]
3.

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

González-Rodríguez A, Mayoral R, Agra N, Valdecantos MP, Pardo V, Miquilena-Colina ME, Vargas-Castrillón J, Lo Iacono O, Corazzari M, Fimia GM, Piacentini M, Muntané J, Boscá L, García-Monzón C, Martín-Sanz P, Valverde ÁM.

Cell Death Dis. 2014 Apr 17;5:e1179. doi: 10.1038/cddis.2014.162.

PMID:
24743734
[PubMed - in process]
Free PMC Article
4.

Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fed foz/foz mice.

Legry V, Van Rooyen DM, Lambert B, Sempoux C, Poekes L, Español-Suñer R, Molendi-Coste O, Horsmans Y, Farrell GC, Leclercq IA.

Clin Sci (Lond). 2014 Oct;127(7):507-18. doi: 10.1042/CS20140026.

PMID:
24766485
[PubMed - in process]
5.

Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet.

Henkel AS, Dewey AM, Anderson KA, Olivares S, Green RM.

Am J Physiol Gastrointest Liver Physiol. 2012 Jul;303(1):G54-9. doi: 10.1152/ajpgi.00052.2012. Epub 2012 May 3.

PMID:
22556147
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice.

Yamaguchi K, Itoh Y, Yokomizo C, Nishimura T, Niimi T, Fujii H, Okanoue T, Yoshikawa T.

Lab Invest. 2010 Aug;90(8):1169-78. doi: 10.1038/labinvest.2010.75. Epub 2010 Apr 5.

PMID:
20368703
[PubMed - indexed for MEDLINE]
Free Article
7.

Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice.

Haque JA, McMahan RS, Campbell JS, Shimizu-Albergine M, Wilson AM, Botta D, Bammler TK, Beyer RP, Montine TJ, Yeh MM, Kavanagh TJ, Fausto N.

Lab Invest. 2010 Dec;90(12):1704-17. doi: 10.1038/labinvest.2010.112. Epub 2010 Jun 14.

PMID:
20548286
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis.

Das S, Seth RK, Kumar A, Kadiiska MB, Michelotti G, Diehl AM, Chatterjee S.

Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(12):G950-63. doi: 10.1152/ajpgi.00235.2013. Epub 2013 Oct 24.

PMID:
24157968
[PubMed - indexed for MEDLINE]
9.

Decoding cell death signals in liver inflammation.

Brenner C, Galluzzi L, Kepp O, Kroemer G.

J Hepatol. 2013 Sep;59(3):583-94. doi: 10.1016/j.jhep.2013.03.033. Epub 2013 Apr 6. Review.

PMID:
23567086
[PubMed - indexed for MEDLINE]
Free Article
10.

The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.

Wortham M, He L, Gyamfi M, Copple BL, Wan YJ.

Dig Dis Sci. 2008 Oct;53(10):2761-74. doi: 10.1007/s10620-007-0193-7. Epub 2008 Feb 26.

PMID:
18299981
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice.

Min AK, Kim MK, Kim HS, Seo HY, Lee KU, Kim JG, Park KG, Lee IK.

Life Sci. 2012 Jan 30;90(5-6):200-5. doi: 10.1016/j.lfs.2011.11.012. Epub 2011 Dec 1.

PMID:
22154902
[PubMed - indexed for MEDLINE]
12.

CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis.

Rahman SM, Schroeder-Gloeckler JM, Janssen RC, Jiang H, Qadri I, Maclean KN, Friedman JE.

Hepatology. 2007 May;45(5):1108-17.

PMID:
17464987
[PubMed - indexed for MEDLINE]
13.

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

Yamaguchi K, Yang L, McCall S, Huang J, Yu XX, Pandey SK, Bhanot S, Monia BP, Li YX, Diehl AM.

Hepatology. 2007 Jun;45(6):1366-74.

PMID:
17476695
[PubMed - indexed for MEDLINE]
14.

A novel mouse model of nonalcoholic steatohepatitis with significant insulin resistance.

Adkins Y, Schie IW, Fedor D, Reddy A, Nguyen S, Zhou P, Kelley DS, Wu J.

Lab Invest. 2013 Dec;93(12):1313-22. doi: 10.1038/labinvest.2013.123. Epub 2013 Oct 21.

PMID:
24145238
[PubMed - indexed for MEDLINE]
15.

Genistein alleviates the development of nonalcoholic steatohepatitis in ApoE(-/-) mice fed a high-fat diet.

Jeon S, Park YJ, Kwon YH.

Mol Nutr Food Res. 2014 Apr;58(4):830-41. doi: 10.1002/mnfr.201300112. Epub 2013 Nov 11.

PMID:
24214843
[PubMed - in process]
16.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
[PubMed - indexed for MEDLINE]
17.

Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesis.

Moles A, Tarrats N, Morales A, Domínguez M, Bataller R, Caballería J, García-Ruiz C, Fernández-Checa JC, Marí M.

Am J Pathol. 2010 Sep;177(3):1214-24. doi: 10.2353/ajpath.2010.091257. Epub 2010 Jul 22.

PMID:
20651240
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.

Caballero F, Fernández A, Matías N, Martínez L, Fucho R, Elena M, Caballeria J, Morales A, Fernández-Checa JC, García-Ruiz C.

J Biol Chem. 2010 Jun 11;285(24):18528-36. doi: 10.1074/jbc.M109.099333. Epub 2010 Apr 15.

PMID:
20395294
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice.

Ahsan MK, Okuyama H, Hoshino Y, Oka S, Masutani H, Yodoi J, Nakamura H.

Antioxid Redox Signal. 2009 Oct;11(10):2573-84. doi: 10.1089/ars.2009.2385.

PMID:
19764881
[PubMed - indexed for MEDLINE]
20.

A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein.

Yimin, Furumaki H, Matsuoka S, Sakurai T, Kohanawa M, Zhao S, Kuge Y, Tamaki N, Chiba H.

Lab Invest. 2012 Feb;92(2):265-81. doi: 10.1038/labinvest.2011.159. Epub 2011 Nov 7.

PMID:
22064320
[PubMed - indexed for MEDLINE]
Free Article

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