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Items: 1 to 20 of 130

1.

Transcriptional regulation of podoplanin expression by Prox1 in lymphatic endothelial cells.

Pan Y, Wang WD, Yago T.

Microvasc Res. 2014 Jul;94:96-102. doi: 10.1016/j.mvr.2014.05.006. Epub 2014 Jun 2.

PMID:
24944097
2.

Prox1 expression is negatively regulated by miR-181 in endothelial cells.

Kazenwadel J, Michael MZ, Harvey NL.

Blood. 2010 Sep 30;116(13):2395-401. doi: 10.1182/blood-2009-12-256297. Epub 2010 Jun 17.

3.

The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells.

Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G.

Genes Dev. 2010 Apr 1;24(7):696-707. doi: 10.1101/gad.1859310.

4.

Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis.

Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK.

Mol Biol Cell. 2006 Feb;17(2):576-84. Epub 2005 Nov 16.

5.

Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium.

Murtomaki A, Uh MK, Choi YK, Kitajewski C, Borisenko V, Kitajewski J, Shawber CJ.

Development. 2013 Jun;140(11):2365-76. doi: 10.1242/dev.083865. Epub 2013 Apr 24.

6.

COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction.

Yamazaki T, Yoshimatsu Y, Morishita Y, Miyazono K, Watabe T.

Genes Cells. 2009 Mar;14(3):425-34. doi: 10.1111/j.1365-2443.2008.01279.x. Epub 2009 Feb 4.

7.

An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells.

Kang J, Yoo J, Lee S, Tang W, Aguilar B, Ramu S, Choi I, Otu HH, Shin JW, Dotto GP, Koh CJ, Detmar M, Hong YK.

Blood. 2010 Jul 8;116(1):140-50. doi: 10.1182/blood-2009-11-252270. Epub 2010 Mar 29.

8.

Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1.

Kilic N, Oliveira-Ferrer L, Neshat-Vahid S, Irmak S, Obst-Pernberg K, Wurmbach JH, Loges S, Kilic E, Weil J, Lauke H, Tilki D, Singer BB, Ergün S.

Blood. 2007 Dec 15;110(13):4223-33. Epub 2007 Aug 30.

9.

COUP-TFII orchestrates venous and lymphatic endothelial identity by homo- or hetero-dimerisation with PROX1.

Aranguren XL, Beerens M, Coppiello G, Wiese C, Vandersmissen I, Lo Nigro A, Verfaillie CM, Gessler M, Luttun A.

J Cell Sci. 2013 Mar 1;126(Pt 5):1164-75. doi: 10.1242/jcs.116293. Epub 2013 Jan 23.

10.

The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors.

Srinivasan RS, Escobedo N, Yang Y, Interiano A, Dillard ME, Finkelstein D, Mukatira S, Gil HJ, Nurmi H, Alitalo K, Oliver G.

Genes Dev. 2014 Oct 1;28(19):2175-87. doi: 10.1101/gad.216226.113.

11.

Repression of interferon-gamma expression in T cells by Prospero-related homeobox protein.

Wang L, Zhu J, Shan S, Qin Y, Kong Y, Liu J, Wang Y, Xie Y.

Cell Res. 2008 Sep;18(9):911-20. doi: 10.1038/cr.2008.275.

PMID:
19160541
12.

Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells.

Pan MR, Chang TM, Chang HC, Su JL, Wang HW, Hung WC.

J Cell Sci. 2009 Sep 15;122(Pt 18):3358-64. doi: 10.1242/jcs.050005. Epub 2009 Aug 25.

13.

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein.

Baxter SA, Cheung DY, Bocangel P, Kim HK, Herbert K, Douville JM, Jangamreddy JR, Zhang S, Eisenstat DD, Wigle JT.

Biochim Biophys Acta. 2011 Jan;1813(1):201-12. doi: 10.1016/j.bbamcr.2010.10.015. Epub 2010 Oct 30.

14.

Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate.

Hong YK, Harvey N, Noh YH, Schacht V, Hirakawa S, Detmar M, Oliver G.

Dev Dyn. 2002 Nov;225(3):351-7.

15.

Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1.

Yoshimatsu Y, Yamazaki T, Mihira H, Itoh T, Suehiro J, Yuki K, Harada K, Morikawa M, Iwata C, Minami T, Morishita Y, Kodama T, Miyazono K, Watabe T.

J Cell Sci. 2011 Aug 15;124(Pt 16):2753-62. doi: 10.1242/jcs.083998.

16.

Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves.

Srinivasan RS, Oliver G.

Genes Dev. 2011 Oct 15;25(20):2187-97. doi: 10.1101/gad.16974811.

17.

Lymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos.

Yang Y, García-Verdugo JM, Soriano-Navarro M, Srinivasan RS, Scallan JP, Singh MK, Epstein JA, Oliver G.

Blood. 2012 Sep 13;120(11):2340-8. doi: 10.1182/blood-2012-05-428607. Epub 2012 Aug 2.

18.

Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis.

Harada K, Yamazaki T, Iwata C, Yoshimatsu Y, Sase H, Mishima K, Morishita Y, Hirashima M, Oike Y, Suda T, Miura N, Watabe T, Miyazono K.

J Cell Sci. 2009 Nov 1;122(Pt 21):3923-30. doi: 10.1242/jcs.052324. Epub 2009 Oct 13.

19.

T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema.

Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M.

EMBO J. 2003 Jul 15;22(14):3546-56.

20.

Transcriptional activation of the Prox1 gene by HIF-1α and HIF-2α in response to hypoxia.

Zhou B, Si W, Su Z, Deng W, Tu X, Wang Q.

FEBS Lett. 2013 Mar 18;587(6):724-31. doi: 10.1016/j.febslet.2013.01.053. Epub 2013 Feb 8.

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