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Results: 1 to 20 of 99

1.

Engineered RNase P ribozymes effectively inhibit human cytomegalovirus gene expression and replication.

Yang Z, Vu GP, Qian H, Chen YC, Wang Y, Reeves M, Zen K, Liu F.

Viruses. 2014 Jun 13;6(6):2376-91. doi: 10.3390/v6062376.

PMID:
24932966
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells.

Zou H, Lee J, Umamoto S, Kilani AF, Kim J, Trang P, Zhou T, Liu F.

J Biol Chem. 2003 Sep 26;278(39):37265-74. Epub 2003 Jul 15.

PMID:
12867424
[PubMed - indexed for MEDLINE]
Free Article
3.

Engineered RNase P ribozymes inhibit gene expression and growth of cytomegalovirus by increasing rate of cleavage and substrate binding.

Trang P, Hsu A, Zhou T, Lee J, Kilani AF, Nepomuceno E, Liu F.

J Mol Biol. 2002 Jan 25;315(4):573-86.

PMID:
11812131
[PubMed - indexed for MEDLINE]
4.

RNase P ribozymes for the studies and treatment of human cytomegalovirus infections.

Trang P, Kilani A, Lee J, Hsu A, Liou K, Kim J, Nassi A, Kim K, Liu F.

J Clin Virol. 2002 Aug;25 Suppl 2:S63-74.

PMID:
12361758
[PubMed - indexed for MEDLINE]
5.

Engineered RNase P ribozymes increase their cleavage activities and efficacies in inhibiting viral gene expression in cells by enhancing the rate of cleavage and binding of the target mRNA.

Zou H, Lee J, Kilani AF, Kim K, Trang P, Kim J, Liu F.

J Biol Chem. 2004 Jul 30;279(31):32063-70. Epub 2004 May 28.

PMID:
15169770
[PubMed - indexed for MEDLINE]
Free Article
6.

Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli.

Trang P, Lee M, Nepomuceno E, Kim J, Zhu H, Liu F.

Proc Natl Acad Sci U S A. 2000 May 23;97(11):5812-7.

PMID:
10811889
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Effective inhibition of human immunodeficiency virus 1 replication by engineered RNase P ribozyme.

Zeng W, Chen YC, Bai Y, Trang P, Vu GP, Lu S, Wu J, Liu F.

PLoS One. 2012;7(12):e51855. doi: 10.1371/journal.pone.0051855. Epub 2012 Dec 26.

PMID:
23300569
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Engineered external guide sequences are highly effective in inducing RNase P for inhibition of gene expression and replication of human cytomegalovirus.

Yang YH, Li H, Zhou T, Kim K, Liu F.

Nucleic Acids Res. 2006 Jan 23;34(2):575-83. Print 2006.

PMID:
16432261
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Salmonella-mediated delivery of RNase P-based ribozymes for inhibition of viral gene expression and replication in human cells.

Bai Y, Li H, Vu GP, Gong H, Umamoto S, Zhou T, Lu S, Liu F.

Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7269-74. doi: 10.1073/pnas.0912813107. Epub 2010 Apr 1.

PMID:
20360564
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Engineered external guide sequences effectively block viral gene expression and replication in cultured cells.

Jiang X, Bai Y, Rider P, Kim K, Zhang CY, Lu S, Liu F.

J Biol Chem. 2011 Jan 7;286(1):322-30. doi: 10.1074/jbc.M110.158857. Epub 2010 Oct 27.

PMID:
20980254
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozyme.

Trang P, Lee J, Kilani AF, Kim J, Liu F.

Nucleic Acids Res. 2001 Dec 15;29(24):5071-8.

PMID:
11812839
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

RNase P ribozyme inhibits cytomegalovirus replication by blocking the expression of viral capsid proteins.

Kim K, Trang P, Umamoto S, Hai R, Liu F.

Nucleic Acids Res. 2004 Jun 25;32(11):3427-34. Print 2004.

PMID:
15220469
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Intracellular expression of engineered RNase P ribozymes effectively blocks gene expression and replication of human cytomegalovirus.

Kim K, Umamoto S, Trang P, Hai R, Liu F.

RNA. 2004 Mar;10(3):438-47.

PMID:
14970389
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

In vitro selection of RNase P ribozymes that efficiently cleave a target mRNA.

Kim K, Liu F.

Methods Mol Biol. 2004;252:399-412.

PMID:
15017066
[PubMed - indexed for MEDLINE]
15.

Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P.

Zhang W, Li H, Li Y, Zeng Z, Li S, Zhang X, Zou Y, Zhou T.

Virol J. 2010 May 18;7:100. doi: 10.1186/1743-422X-7-100.

PMID:
20482805
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Ribonuclease P-mediated inhibition of human cytomegalovirus gene expression and replication induced by engineered external guide sequences.

Jiang X, Chen YC, Gong H, Trang P, Lu S, Liu F.

RNA Biol. 2012 Sep;9(9):1186-95. doi: 10.4161/rna.21724. Epub 2012 Sep 1.

PMID:
23018778
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Expression of an RNase P ribozyme against the mRNA encoding human cytomegalovirus protease inhibits viral capsid protein processing and growth.

Trang P, Kim K, Zhu J, Liu F.

J Mol Biol. 2003 May 16;328(5):1123-35.

PMID:
12729746
[PubMed - indexed for MEDLINE]
18.

Targeting mRNAs by engineered sequence-specific RNase P ribozymes.

Bai Y, Sunkara N, Liu F.

Methods Mol Biol. 2012;848:357-68. doi: 10.1007/978-1-61779-545-9_22.

PMID:
22315080
[PubMed - indexed for MEDLINE]
19.

RNase P ribozyme as an antiviral agent against human cytomegalovirus.

Trang P, Liu F.

Methods Mol Biol. 2004;252:437-50.

PMID:
15017069
[PubMed - indexed for MEDLINE]
20.

RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture.

Kilani AF, Trang P, Jo S, Hsu A, Kim J, Nepomuceno E, Liou K, Liu F.

J Biol Chem. 2000 Apr 7;275(14):10611-22.

PMID:
10744757
[PubMed - indexed for MEDLINE]
Free Article
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