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Interleukin-6 promotes systemic lupus erythematosus progression with Treg suppression approach in a murine systemic lupus erythematosus model.

Mao X, Wu Y, Diao H, Hao J, Tian G, Jia Z, Li Z, Xiong S, Wu Z, Wang P, Zhao L, Yin Z.

Clin Rheumatol. 2014 Nov;33(11):1585-93. doi: 10.1007/s10067-014-2717-9. Epub 2014 Jun 15.


Increased CD45RA+ FoxP3(low) regulatory T cells with impaired suppressive function in patients with systemic lupus erythematosus.

Pan X, Yuan X, Zheng Y, Wang W, Shan J, Lin F, Jiang G, Yang YH, Wang D, Xu D, Shen L.

PLoS One. 2012;7(4):e34662. doi: 10.1371/journal.pone.0034662. Epub 2012 Apr 10.


Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- mice.

Wilhelm AJ, Rhoads JP, Wade NS, Major AS.

Ann Rheum Dis. 2015 Apr;74(4):778-85. doi: 10.1136/annrheumdis-2013-203759. Epub 2014 Jan 6.


Anti-DNA Ig peptides promote Treg cell activity in systemic lupus erythematosus patients.

Hahn BH, Anderson M, Le E, La Cava A.

Arthritis Rheum. 2008 Aug;58(8):2488-97. doi: 10.1002/art.23609.


Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA.

Qiao B, Wu J, Chu YW, Wang Y, Wang DP, Wu HS, Xiong SD.

Rheumatology (Oxford). 2005 Sep;44(9):1108-14. Epub 2005 Apr 19.


Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus.

Liang B, Gardner DB, Griswold DE, Bugelski PJ, Song XY.

Immunology. 2006 Nov;119(3):296-305.


Altered homeostasis of CD4(+) FoxP3(+) regulatory T-cell subpopulations in systemic lupus erythematosus.

Suen JL, Li HT, Jong YJ, Chiang BL, Yen JH.

Immunology. 2009 Jun;127(2):196-205. doi: 10.1111/j.1365-2567.2008.02937.x. Epub 2008 Sep 16.


The percentage of FoxP3+Helios+ Treg cells correlates positively with disease activity in systemic lupus erythematosus.

Golding A, Hasni S, Illei G, Shevach EM.

Arthritis Rheum. 2013 Nov;65(11):2898-906. doi: 10.1002/art.38119. Erratum in: Arthritis Rheum. 2014 Jun;66(6):1671.


DNA hypomethylation is crucial for apoptotic DNA to induce systemic lupus erythematosus-like autoimmune disease in SLE-non-susceptible mice.

Wen ZK, Xu W, Xu L, Cao QH, Wang Y, Chu YW, Xiong SD.

Rheumatology (Oxford). 2007 Dec;46(12):1796-803.


Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells.

Yan B, Ye S, Chen G, Kuang M, Shen N, Chen S.

Arthritis Rheum. 2008 Mar;58(3):801-12. doi: 10.1002/art.23268.


Regulatory T cells in systemic lupus erythematosus.

Ohl K, Tenbrock K.

Eur J Immunol. 2015 Feb;45(2):344-55. doi: 10.1002/eji.201344280. Epub 2014 Dec 15. Review.


Imbalance of different types of CD4(+) forkhead box protein 3 (FoxP3)(+) T cells in patients with new-onset systemic lupus erythematosus.

Ma L, Zhao P, Jiang Z, Shan Y, Jiang Y.

Clin Exp Immunol. 2013 Dec;174(3):345-55. doi: 10.1111/cei.12189.


Transgenic overexpression of anti-double-stranded DNA autoantibody and activation of Toll-like receptor 4 in mice induce severe systemic lupus erythematosus syndromes.

Lee TP, Tang SJ, Wu MF, Song YC, Yu CL, Sun KH.

J Autoimmun. 2010 Dec;35(4):358-67. doi: 10.1016/j.jaut.2010.07.007. Epub 2010 Sep 15.


Defective response of CD4(+) T cells to retinoic acid and TGFβ in systemic lupus erythematosus.

Sobel ES, Brusko TM, Butfiloski EJ, Hou W, Li S, Cuda CM, Abid AN, Reeves WH, Morel L.

Arthritis Res Ther. 2011 Jun 27;13(3):R106. doi: 10.1186/ar3387.

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