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Salidroside protects Caenorhabditis elegans neurons from polyglutamine-mediated toxicity by reducing oxidative stress.

Xiao L, Li H, Zhang J, Yang F, Huang A, Deng J, Liang M, Ma F, Hu M, Huang Z.

Molecules. 2014 Jun 10;19(6):7757-69. doi: 10.3390/molecules19067757.


miR-103 Regulates Oxidative Stress by Targeting the BCL2/Adenovirus E1B 19 kDa Interacting Protein 3 in HUVECs.

Xu MC, Gao XF, Ruan C, Ge ZR, Lu JD, Zhang JJ, Zhang Y, Wang L, Shi HM.

Oxid Med Cell Longev. 2015;2015:489647. doi: 10.1155/2015/489647. Epub 2015 Apr 27.


Salidroside inhibits oxygen glucose deprivation (OGD)/re-oxygenation-induced H9c2 cell necrosis through activating of Akt-Nrf2 signaling.

Zheng K, Sheng Z, Li Y, Lu H.

Biochem Biophys Res Commun. 2014 Aug 15;451(1):79-85. doi: 10.1016/j.bbrc.2014.07.072. Epub 2014 Jul 22.


Salidroside stimulates mitochondrial biogenesis and protects against H₂O₂-induced endothelial dysfunction.

Xing S, Yang X, Li W, Bian F, Wu D, Chi J, Xu G, Zhang Y, Jin S.

Oxid Med Cell Longev. 2014;2014:904834. doi: 10.1155/2014/904834. Epub 2014 Apr 24.


MADP, a salidroside analog, protects hippocampal neurons from glutamate induced apoptosis.

Xian H, Zhao J, Zheng Y, Wang M, Huang J, Wu B, Sun C, Yang Y.

Life Sci. 2014 May 8;103(1):34-40. doi: 10.1016/j.lfs.2014.02.040. Epub 2014 Mar 11.


Aqueous extract of Gardenia jasminoides targeting oxidative stress to reduce polyQ aggregation in cell models of spinocerebellar ataxia 3.

Chang KH, Chen WL, Wu YR, Lin TH, Wu YC, Chao CY, Lin JY, Lee LC, Chen YC, Lee-Chen GJ, Chen CM.

Neuropharmacology. 2014 Jun;81:166-75. doi: 10.1016/j.neuropharm.2014.01.032. Epub 2014 Jan 31.


Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart.

Melkani GC, Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K.

PLoS Genet. 2013;9(12):e1004024. doi: 10.1371/journal.pgen.1004024. Epub 2013 Dec 19.


Phthalates induce neurotoxicity affecting locomotor and thermotactic behaviors and AFD neurons through oxidative stress in Caenorhabditis elegans.

Tseng IL, Yang YF, Yu CW, Li WH, Liao VH.

PLoS One. 2013 Dec 12;8(12):e82657. doi: 10.1371/journal.pone.0082657. eCollection 2013. Erratum in: PLoS One. 2014;9(6):e99945.


Binding to WGR domain by salidroside activates PARP1 and protects hematopoietic stem cells from oxidative stress.

Li X, Erden O, Li L, Ye Q, Wilson A, Du W.

Antioxid Redox Signal. 2014 Apr 20;20(12):1853-65. doi: 10.1089/ars.2013.5600. Epub 2014 Mar 5.


Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegans model for polyglutamine disease.

Gidalevitz T, Wang N, Deravaj T, Alexander-Floyd J, Morimoto RI.

BMC Biol. 2013 Sep 30;11:100. doi: 10.1186/1741-7007-11-100.


Salidroside improves doxorubicin-induced cardiac dysfunction by suppression of excessive oxidative stress and cardiomyocyte apoptosis.

Wang XL, Wang X, Xiong LL, Zhu Y, Chen HL, Chen JX, Wang XX, Li RL, Guo ZY, Li P, Jiang W.

J Cardiovasc Pharmacol. 2013 Dec;62(6):512-23. doi: 10.1097/FJC.0000000000000009.


Salidroside inhibits endogenous hydrogen peroxide induced cytotoxicity of endothelial cells.

Zhao X, Jin L, Shen N, Xu B, Zhang W, Zhu H, Luo Z.

Biol Pharm Bull. 2013;36(11):1773-8. Epub 2013 Aug 22.


A huntingtin peptide inhibits polyQ-huntingtin associated defects.

Arribat Y, Bonneaud N, Talmat-Amar Y, Layalle S, Parmentier ML, Maschat F.

PLoS One. 2013 Jul 4;8(7):e68775. doi: 10.1371/journal.pone.0068775. Print 2013.


Salidroside reduces cold-induced mucin production by inhibiting TRPM8 activation.

Li Q, Zhou XD, Kolosov VP, Perelman JM.

Int J Mol Med. 2013 Sep;32(3):637-46. doi: 10.3892/ijmm.2013.1434. Epub 2013 Jul 5.


Pharmacological activation of Sirt1 ameliorates polyglutamine-induced toxicity through the regulation of autophagy.

Shin BH, Lim Y, Oh HJ, Park SM, Lee SK, Ahnn J, Kim do H, Song WK, Kwak TH, Park WJ.

PLoS One. 2013 Jun 10;8(6):e64953. doi: 10.1371/journal.pone.0064953. Print 2013.


Inhibitory effects of salidroside and paeonol on tyrosinase activity and melanin synthesis in mouse B16F10 melanoma cells and ultraviolet B-induced pigmentation in guinea pig skin.

Peng LH, Liu S, Xu SY, Chen L, Shan YH, Wei W, Liang WQ, Gao JQ.

Phytomedicine. 2013 Sep 15;20(12):1082-7. doi: 10.1016/j.phymed.2013.04.015. Epub 2013 Jun 7.


Salidroside protects against hydrogen peroxide-induced injury in HUVECs via the regulation of REDD1 and mTOR activation.

Xu MC, Shi HM, Wang H, Gao XF.

Mol Med Rep. 2013 Jul;8(1):147-53. doi: 10.3892/mmr.2013.1468. Epub 2013 May 9.


Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases.

Muñoz-Lobato F, Rodríguez-Palero MJ, Naranjo-Galindo FJ, Shephard F, Gaffney CJ, Szewczyk NJ, Hamamichi S, Caldwell KA, Caldwell GA, Link CD, Miranda-Vizuete A.

Antioxid Redox Signal. 2014 Jan 10;20(2):217-35. doi: 10.1089/ars.2012.5051. Epub 2013 Jul 3.


Salidroside improves homocysteine-induced endothelial dysfunction by reducing oxidative stress.

Leung SB, Zhang H, Lau CW, Huang Y, Lin Z.

Evid Based Complement Alternat Med. 2013;2013:679635. doi: 10.1155/2013/679635. Epub 2013 Mar 26.

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