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Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.

Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E, Condron M, Tan YH, Baum J, Scheres SH.

Elife. 2014 Jun 9;3. doi: 10.7554/eLife.03080.


Structure of the E. coli ribosome-EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM.

Fischer N, Neumann P, Konevega AL, Bock LV, Ficner R, Rodnina MV, Stark H.

Nature. 2015 Apr 23;520(7548):567-70. doi: 10.1038/nature14275. Epub 2015 Feb 23.


Structural insights into pre-translocation ribosome motions.

Flores SC, Altman R.

Pac Symp Biocomput. 2011:205-11.


A class of tricyclic compounds blocking malaria parasite oocyst development and transmission.

Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson KC, Lambert LE, Long C, Austin CP, Wu Y, Su XZ.

Antimicrob Agents Chemother. 2013 Jan;57(1):425-35. doi: 10.1128/AAC.00920-12. Epub 2012 Nov 5.


In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin.

Sidhu AB, Sun Q, Nkrumah LJ, Dunne MW, Sacchettini JC, Fidock DA.

J Biol Chem. 2007 Jan 26;282(4):2494-504. Epub 2006 Nov 15.


The CCA-end of P-tRNA Contacts Both the Human RPL36AL and the A-site Bound Translation Termination Factor eRF1 at the Peptidyl Transferase Center of the Human 80S Ribosome.

Hountondji C, Bulygin K, Créchet JB, Woisard A, Tuffery P, Nakayama J, Frolova L, Nierhaus KH, Karpova G, Baouz S.

Open Biochem J. 2014 Jul 11;8:52-67. doi: 10.2174/1874091X01408010052. eCollection 2014.


Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor.

Spahn CM, Jan E, Mulder A, Grassucci RA, Sarnow P, Frank J.

Cell. 2004 Aug 20;118(4):465-75.


Detection of high levels of mutations involved in anti-malarial drug resistance in Plasmodium falciparum and Plasmodium vivax at a rural hospital in southern Ethiopia.

Mula P, Fernández-Martínez A, de Lucio A, Ramos JM, Reyes F, González V, Benito A, Berzosa P.

Malar J. 2011 Aug 2;10:214. doi: 10.1186/1475-2875-10-214.


Antisense oligonucleotides targeting malarial aldolase inhibit the asexual erythrocytic stages of Plasmodium falciparum.

Wanidworanun C, Nagel RL, Shear HL.

Mol Biochem Parasitol. 1999 Jul 30;102(1):91-101.


Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution.

Arenz S, Nguyen F, Beckmann R, Wilson DN.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5401-6. doi: 10.1073/pnas.1501775112. Epub 2015 Apr 13.


Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins.

Sharma MR, Wilson DN, Datta PP, Barat C, Schluenzen F, Fucini P, Agrawal RK.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19315-20. Epub 2007 Nov 27.


Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi and evaluation of its inhibitor as a candidate drug.

Pallavi R, Roy N, Nageshan RK, Talukdar P, Pavithra SR, Reddy R, Venketesh S, Kumar R, Gupta AK, Singh RK, Yadav SC, Tatu U.

J Biol Chem. 2010 Dec 3;285(49):37964-75. doi: 10.1074/jbc.M110.155317. Epub 2010 Sep 13.


Global conformational changes of ribosome observed by normal mode fitting for 3D Cryo-EM structures.

Matsumoto A, Ishida H.

Structure. 2009 Dec 9;17(12):1605-13. doi: 10.1016/j.str.2009.09.017.


Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum.

Parquet V, Henry M, Wurtz N, Dormoi J, Briolant S, Gil M, Baret E, Amalvict R, Rogier C, Pradines B.

Malar J. 2010 May 25;9:139. doi: 10.1186/1475-2875-9-139.


Cryo-EM structure of the archaeal 50S ribosomal subunit in complex with initiation factor 6 and implications for ribosome evolution.

Greber BJ, Boehringer D, Godinic-Mikulcic V, Crnkovic A, Ibba M, Weygand-Durasevic I, Ban N.

J Mol Biol. 2012 May 4;418(3-4):145-60. doi: 10.1016/j.jmb.2012.01.018. Epub 2012 Jan 27.


Malaria, anti malarial drugs and the role of melatonin.

Srinivasan V, Mohamed M, Zakaria R, Ahmad AH.

Infect Disord Drug Targets. 2012 Oct;12(5):371-9. Review.


Proteomic approaches to studying drug targets and resistance in Plasmodium.

Cooper RA, Carucci DJ.

Curr Drug Targets Infect Disord. 2004 Mar;4(1):41-51. Review.


Molecular characterization of Plasmodium falciparum uracil-DNA glycosylase and its potential as a new anti-malarial drug target.

Suksangpleng T, Leartsakulpanich U, Moonsom S, Siribal S, Boonyuen U, Wright GE, Chavalitshewinkoon-Petmitr P.

Malar J. 2014 Apr 17;13:149. doi: 10.1186/1475-2875-13-149.

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