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Results: 1 to 20 of 88

Related Citations for PubMed (Select 24908670)


Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.

Hasumi Y, Baba M, Hasumi H, Huang Y, Lang M, Reindorf R, Oh HB, Sciarretta S, Nagashima K, Haines DC, Schneider MD, Adelstein RS, Schmidt LS, Sadoshima J, Marston Linehan W.

Hum Mol Genet. 2014 Nov 1;23(21):5706-19. doi: 10.1093/hmg/ddu286. Epub 2014 Jun 6.


Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells.

Khabibullin D, Medvetz DA, Pinilla M, Hariharan V, Li C, Hergrueter A, Laucho Contreras M, Zhang E, Parkhitko A, Yu JJ, Owen CA, Huang H, Baron RM, Henske EP.

Physiol Rep. 2014 Aug 12;2(8). pii: e12107. doi: 10.14814/phy2.12107. Print 2014 Aug 1.


Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.

Hasumi H, Baba M, Hasumi Y, Huang Y, Oh H, Hughes RM, Klein ME, Takikita S, Nagashima K, Schmidt LS, Linehan WM.

J Natl Cancer Inst. 2012 Nov 21;104(22):1750-64. doi: 10.1093/jnci/djs418. Epub 2012 Nov 12.


Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.

Baba M, Hong SB, Sharma N, Warren MB, Nickerson ML, Iwamatsu A, Esposito D, Gillette WK, Hopkins RF 3rd, Hartley JL, Furihata M, Oishi S, Zhen W, Burke TR Jr, Linehan WM, Schmidt LS, Zbar B.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15552-7. Epub 2006 Oct 6.


The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy.

Yang CS, Kim JJ, Lee HM, Jin HS, Lee SH, Park JH, Kim SJ, Kim JM, Han YM, Lee MS, Kweon GR, Shong M, Jo EK.

Autophagy. 2014 May;10(5):785-802. doi: 10.4161/auto.28072. Epub 2014 Feb 25.


AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1.

Li Y, Chen C, Yao F, Su Q, Liu D, Xue R, Dai G, Fang R, Zeng J, Chen Y, Huang H, Ma Y, Li W, Zhang L, Liu C, Dong Y.

Arch Biochem Biophys. 2014 Sep 15;558:79-86. doi: 10.1016/ Epub 2014 Jul 4.


Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway.

Piao X, Kobayashi T, Wang L, Shiono M, Takagi Y, Sun G, Abe M, Hagiwara Y, Zhang D, Okimoto K, Kouchi M, Matsumoto I, Hino O.

Biochem Biophys Res Commun. 2009 Nov 6;389(1):16-21. doi: 10.1016/j.bbrc.2009.08.070. Epub 2009 Aug 18.


Folliculin controls lung alveolar enlargement and epithelial cell survival through E-cadherin, LKB1, and AMPK.

Goncharova EA, Goncharov DA, James ML, Atochina-Vasserman EN, Stepanova V, Hong SB, Li H, Gonzales L, Baba M, Linehan WM, Gow AJ, Margulies S, Guttentag S, Schmidt LS, Krymskaya VP.

Cell Rep. 2014 Apr 24;7(2):412-23. doi: 10.1016/j.celrep.2014.03.025. Epub 2014 Apr 13.


Antagonistic control of muscle cell size by AMPK and mTORC1.

Mounier R, Lantier L, Leclerc J, Sotiropoulos A, Foretz M, Viollet B.

Cell Cycle. 2011 Aug 15;10(16):2640-6. Epub 2011 Aug 15.


Folliculin regulates ampk-dependent autophagy and metabolic stress survival.

Possik E, Jalali Z, Nouët Y, Yan M, Gingras MC, Schmeisser K, Panaite L, Dupuy F, Kharitidi D, Chotard L, Jones RG, Hall DH, Pause A.

PLoS Genet. 2014 Apr 24;10(4):e1004273. doi: 10.1371/journal.pgen.1004273. eCollection 2014 Apr.


Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA.

Lim TH, Fujikane R, Sano S, Sakagami R, Nakatsu Y, Tsuzuki T, Sekiguchi M, Hidaka M.

DNA Repair (Amst). 2012 Mar 1;11(3):259-66. doi: 10.1016/j.dnarep.2011.11.006. Epub 2011 Dec 29.


Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.

Chan AY, Soltys CL, Young ME, Proud CG, Dyck JR.

J Biol Chem. 2004 Jul 30;279(31):32771-9. Epub 2004 May 24.


Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction.

Ikeda Y, Sato K, Pimentel DR, Sam F, Shaw RJ, Dyck JR, Walsh K.

J Biol Chem. 2009 Dec 18;284(51):35839-49. doi: 10.1074/jbc.M109.057273. Epub .


The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure.

Xu N, Guan S, Chen Z, Yu Y, Xie J, Pan FY, Zhao NW, Liu L, Yang ZZ, Gao X, Xu B, Li CJ.

J Pathol. 2015 Apr;235(5):672-85. doi: 10.1002/path.4480. Epub 2015 Jan 7.


Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase.

Xing Y, Musi N, Fujii N, Zou L, Luptak I, Hirshman MF, Goodyear LJ, Tian R.

J Biol Chem. 2003 Aug 1;278(31):28372-7. Epub 2003 May 23.


Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase.

Stuck BJ, Lenski M, Böhm M, Laufs U.

J Biol Chem. 2008 Nov 21;283(47):32562-9. doi: 10.1074/jbc.M801904200. Epub 2008 Sep 12.


Role of AMP-activated protein kinase in healthy and diseased hearts.

Dolinsky VW, Dyck JR.

Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2557-69. Epub 2006 Jul 14. Review.


Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.

Shende P, Plaisance I, Morandi C, Pellieux C, Berthonneche C, Zorzato F, Krishnan J, Lerch R, Hall MN, Rüegg MA, Pedrazzini T, Brink M.

Circulation. 2011 Mar 15;123(10):1073-82. doi: 10.1161/CIRCULATIONAHA.110.977066. Epub 2011 Feb 28.


Does long-term metformin treatment increase cardiac lipoprotein lipase?

Hauton D.

Metabolism. 2011 Jan;60(1):32-42. doi: 10.1016/j.metabol.2009.12.015. Epub 2010 Feb 12.


AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.

Li J, Miller EJ, Ninomiya-Tsuji J, Russell RR 3rd, Young LH.

Circ Res. 2005 Oct 28;97(9):872-9. Epub 2005 Sep 22.

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