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Results: 1 to 20 of 101

1.

CRIF1 deficiency induces p66shc-mediated oxidative stress and endothelial activation.

Nagar H, Jung SB, Kwon SK, Park JB, Shong M, Song HJ, Jeon BH, Irani K, Kim CS.

PLoS One. 2014 Jun 6;9(6):e98670. doi: 10.1371/journal.pone.0098670. eCollection 2014.

PMID:
24906005
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.

Vikram A, Kim YR, Kumar S, Naqvi A, Hoffman TA, Kumar A, Miller FJ Jr, Kim CS, Irani K.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2301-9. doi: 10.1161/ATVBAHA.114.304338. Epub 2014 Aug 21.

PMID:
25147340
[PubMed - indexed for MEDLINE]
3.

Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc.

Kim CS, Kim YR, Naqvi A, Kumar S, Hoffman TA, Jung SB, Kumar A, Jeon BH, McNamara DM, Irani K.

Cardiovasc Res. 2011 Dec 1;92(3):466-75. doi: 10.1093/cvr/cvr250. Epub 2011 Sep 20.

PMID:
21933910
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc.

Arany I, Clark J, Reed DK, Juncos LA.

Nephrol Dial Transplant. 2013 Jun;28(6):1417-25. doi: 10.1093/ndt/gfs596. Epub 2013 Jan 16.

PMID:
23328708
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients.

Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR.

Int J Biochem Cell Biol. 2013 Jan;45(1):141-50. doi: 10.1016/j.biocel.2012.07.020. Epub 2012 Jul 31.

PMID:
22885148
[PubMed - indexed for MEDLINE]
6.

Novel role of p66Shc in ROS-dependent VEGF signaling and angiogenesis in endothelial cells.

Oshikawa J, Kim SJ, Furuta E, Caliceti C, Chen GF, McKinney RD, Kuhr F, Levitan I, Fukai T, Ushio-Fukai M.

Am J Physiol Heart Circ Physiol. 2012 Feb 1;302(3):H724-32. doi: 10.1152/ajpheart.00739.2011. Epub 2011 Nov 18.

PMID:
22101521
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

p66SHC-mediated mitochondrial dysfunction in renal proximal tubule cells during oxidative injury.

Arany I, Faisal A, Clark JS, Vera T, Baliga R, Nagamine Y.

Am J Physiol Renal Physiol. 2010 May;298(5):F1214-21. doi: 10.1152/ajprenal.00639.2009. Epub 2010 Jan 6.

PMID:
20053790
[PubMed - indexed for MEDLINE]
Free Article
8.

The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation.

Frijhoff J, Dagnell M, Augsten M, Beltrami E, Giorgio M, Östman A.

Free Radic Biol Med. 2014 Mar;68:268-77. doi: 10.1016/j.freeradbiomed.2013.12.022. Epub 2013 Dec 27.

PMID:
24378437
[PubMed - indexed for MEDLINE]
9.

The role of p66shc in taxol- and dichloroacetic acid-dependent renal toxicity.

Arany I, Clark JS, Reed D, Szabó I, Ember I, Juncos LA.

Anticancer Res. 2013 Aug;33(8):3119-22.

PMID:
23898068
[PubMed - indexed for MEDLINE]
10.

p66Shc-dependent apoptosis requires Lck and CamKII activity.

Patrussi L, Giommoni N, Pellegrini M, Gamberucci A, Baldari CT.

Apoptosis. 2012 Feb;17(2):174-86. doi: 10.1007/s10495-011-0663-4.

PMID:
21983898
[PubMed - indexed for MEDLINE]
11.

[P66shc action on resistance of colon carcinoma RKO cells to oxidative stress].

Galimov ER, Sidorenko AS, Tereshkova AV, Pletiushkina OIu, Cherniak BV, Chumakov PM.

Mol Biol (Mosk). 2012 Jan-Feb;46(1):139-46. Russian.

PMID:
22642111
[PubMed - indexed for MEDLINE]
12.

CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane.

Kim SJ, Kwon MC, Ryu MJ, Chung HK, Tadi S, Kim YK, Kim JM, Lee SH, Park JH, Kweon GR, Ryu SW, Jo YS, Lee CH, Hatakeyama H, Goto Y, Yim YH, Chung J, Kong YY, Shong M.

Cell Metab. 2012 Aug 8;16(2):274-83. doi: 10.1016/j.cmet.2012.06.012. Epub 2012 Jul 19.

PMID:
22819524
[PubMed - indexed for MEDLINE]
Free Article
13.

Reactive oxygen species induced by p66Shc longevity protein mediate nongenomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells.

Veeramani S, Chou YW, Lin FC, Muniyan S, Lin FF, Kumar S, Xie Y, Lele SM, Tu Y, Lin MF.

Free Radic Biol Med. 2012 Jul 1;53(1):95-108. doi: 10.1016/j.freeradbiomed.2012.03.024. Epub 2012 Apr 16.

PMID:
22561705
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The role of p66Shc deletion in age-associated arterial dysfunction and disease states.

Camici GG, Cosentino F, Tanner FC, Lüscher TF.

J Appl Physiol (1985). 2008 Nov;105(5):1628-31. doi: 10.1152/japplphysiol.90579.2008. Epub 2008 Sep 4. Review.

PMID:
18772327
[PubMed - indexed for MEDLINE]
Free Article
15.

The Lifespan-regulator p66Shc in mitochondria: redox enzyme or redox sensor?

Gertz M, Steegborn C.

Antioxid Redox Signal. 2010 Nov 1;13(9):1417-28. doi: 10.1089/ars.2010.3147. Review.

PMID:
20214499
[PubMed - indexed for MEDLINE]
16.

p66Shc mediates high-glucose and angiotensin II-induced oxidative stress renal tubular injury via mitochondrial-dependent apoptotic pathway.

Sun L, Xiao L, Nie J, Liu FY, Ling GH, Zhu XJ, Tang WB, Chen WC, Xia YC, Zhan M, Ma MM, Peng YM, Liu H, Liu YH, Kanwar YS.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F1014-25. doi: 10.1152/ajprenal.00414.2010. Epub 2010 Aug 25.

PMID:
20739391
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction.

Zhou S, Chen HZ, Wan YZ, Zhang QJ, Wei YS, Huang S, Liu JJ, Lu YB, Zhang ZQ, Yang RF, Zhang R, Cai H, Liu DP, Liang CC.

Circ Res. 2011 Sep 2;109(6):639-48. doi: 10.1161/CIRCRESAHA.111.243592. Epub 2011 Jul 21.

PMID:
21778425
[PubMed - indexed for MEDLINE]
Free Article
18.

p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes.

Guo J, Gertsberg Z, Ozgen N, Steinberg SF.

Circ Res. 2009 Mar 13;104(5):660-9. doi: 10.1161/CIRCRESAHA.108.186288. Epub 2009 Jan 22.

PMID:
19168439
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Apoptosis and oxidative stress-related diseases: the p66Shc connection.

Pellegrini M, Baldari CT.

Curr Mol Med. 2009 Apr;9(3):392-8. Review.

PMID:
19355920
[PubMed - indexed for MEDLINE]
20.

Transcriptional repression of Kruppel like factor-2 by the adaptor protein p66shc.

Kumar A, Hoffman TA, Dericco J, Naqvi A, Jain MK, Irani K.

FASEB J. 2009 Dec;23(12):4344-52. doi: 10.1096/fj.09-138743. Epub 2009 Aug 20.

PMID:
19696221
[PubMed - indexed for MEDLINE]
Free PMC Article

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