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Items: 1 to 20 of 104

1.

The glucocorticoid dexamethasone inhibits U937 cell adhesion and neutrophil release via RhoA/ROCK1-dependent and independent pathways.

Liu D, Xiong R, Chen X, Li P, Ning Y, Peng Y, Zhao Y, Yang N, Zhou Y.

Cell Physiol Biochem. 2014;33(6):1654-62. doi: 10.1159/000362948. Epub 2014 May 16.

PMID:
24902944
2.

Dexamethasone inhibits U937 cell adhesion via the down-regulation of ROCK1 activity.

Liu D, Chen XY, Xiong RP, Ning YL, Li P, Peng Y, Liu P, Zhao Y, Yang N, Zhou YG.

Acta Biochim Pol. 2012;59(4):557-60. Epub 2012 Oct 16.

3.

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage.

Arita R, Hata Y, Nakao S, Kita T, Miura M, Kawahara S, Zandi S, Almulki L, Tayyari F, Shimokawa H, Hafezi-Moghadam A, Ishibashi T.

Diabetes. 2009 Jan;58(1):215-26. doi: 10.2337/db08-0762. Epub 2008 Oct 7.

4.

ROCK1 feedback regulation of the upstream small GTPase RhoA.

Tang AT, Campbell WB, Nithipatikom K.

Cell Signal. 2012 Jul;24(7):1375-80. doi: 10.1016/j.cellsig.2012.03.005. Epub 2012 Mar 11.

5.

Involvement of RhoA/ROCK1 signaling pathway in hyperglycemia-induced microvascular endothelial dysfunction in diabetic retinopathy.

Lu QY, Chen W, Lu L, Zheng Z, Xu X.

Int J Clin Exp Pathol. 2014 Sep 15;7(10):7268-77. eCollection 2014.

6.

Involvement of RhoA/Rho-associated kinase signal transduction pathway in dexamethasone-induced alterations in aqueous outflow.

Fujimoto T, Inoue T, Kameda T, Kasaoka N, Inoue-Mochita M, Tsuboi N, Tanihara H.

Invest Ophthalmol Vis Sci. 2012 Oct 11;53(11):7097-108. doi: 10.1167/iovs.12-9989. Erratum in: Invest Ophthalmol Vis Sci. 2015 Mar;56(3):1593.

PMID:
22969074
7.

Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells.

Ohta T, Takahashi T, Shibuya T, Amita M, Henmi N, Takahashi K, Kurachi H.

Cancer Biol Ther. 2012 Jan 1;13(1):25-33. doi: 10.4161/cbt.13.1.18440.

PMID:
22336585
8.

RhoA/ROCK may involve in cardiac hypertrophy induced by experimental hyperthyroidism.

Na W, Peng G, Jianping Z, Yanzhong C, Shengjiang G, Li C.

Toxicol Ind Health. 2012 Oct;28(9):831-9. Epub 2011 Nov 9.

PMID:
22072613
9.
10.

Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.

Rashid M, Tawara S, Fukumoto Y, Seto M, Yano K, Shimokawa H.

Circ J. 2009 Feb;73(2):361-70. Epub 2008 Dec 8.

11.

ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion.

Li H, Peng W, Jian W, Li Y, Li Q, Li W, Xu Y.

Cardiovasc Diabetol. 2012 Jun 13;11:65. doi: 10.1186/1475-2840-11-65.

12.

RhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo.

Li G, Liu L, Shan C, Cheng Q, Budhraja A, Zhou T, Cui H, Gao N.

Cell Death Dis. 2014 Jan 16;5:e998. doi: 10.1038/cddis.2013.519.

13.

Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions.

Saito M, Ohmasa F, Shomori K, Dimitriadis F, Ohiwa H, Shimizu S, Tsounapi P, Kinoshita Y, Satoh K.

Mol Cell Biochem. 2011 Dec;358(1-2):207-13. doi: 10.1007/s11010-011-0936-9. Epub 2011 Jul 1.

PMID:
21720764
14.

A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat.

Sung JK, Miao L, Calvert JW, Huang L, Louis Harkey H, Zhang JH.

Brain Res. 2003 Jan 3;959(1):29-38.

PMID:
12480155
15.

Activation of ERM-family proteins via RhoA-ROCK signaling increases intestinal P-gp expression and leads to attenuation of oral morphine analgesia.

Kobori T, Harada S, Nakamoto K, Tokuyama S.

J Pharm Sci. 2013 Mar;102(3):1095-105. doi: 10.1002/jps.23441. Epub 2013 Jan 9.

PMID:
23303573
16.
17.

[Fasudil inhibits HSC adhesion, migration and proliferation via Rho/ROCK pathway].

Wang YZ, Jiang HQ, Hu CX, Chen X.

Zhonghua Gan Zang Bing Za Zhi. 2006 Nov;14(11):821-3. Chinese.

PMID:
17125608
18.

2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells.

Rigassi L, Barchiesi Bozzolo F, Lucchinetti E, Zaugg M, Fingerle J, Rosselli M, Imthurn B, Jackson EK, Dubey RK.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E995-1007. doi: 10.1152/ajpendo.00267.2015. Epub 2015 Oct 20.

PMID:
26487003
19.

Inhibition of formyl peptide-stimulated phospholipase D activation by Fal-002-2 via blockade of the Arf6, RhoA and protein kinase C signaling pathways in rat neutrophils.

Tsai YR, Huang LJ, Lin HY, Hung YJ, Lee MR, Kuo SC, Hsu MF, Wang JP.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):507-19. doi: 10.1007/s00210-013-0851-6. Epub 2013 Mar 23.

PMID:
23525454
20.

The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models.

Ying H, Biroc SL, Li WW, Alicke B, Xuan JA, Pagila R, Ohashi Y, Okada T, Kamata Y, Dinter H.

Mol Cancer Ther. 2006 Sep;5(9):2158-64.

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