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Items: 1 to 20 of 185

1.

Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation.

Takano S, Fukasawa M, Maekawa S, Kadokura M, Miura M, Shindo H, Takahashi E, Sato T, Enomoto N.

PLoS One. 2014 Jun 4;9(6):e98718. doi: 10.1371/journal.pone.0098718. eCollection 2014.

2.

Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype.

Ideno N, Ohtsuka T, Kono H, Fujiwara K, Oda Y, Aishima S, Ito T, Ishigami K, Tokunaga S, Ohuchida K, Takahata S, Nakamura M, Mizumoto K, Tanaka M.

Ann Surg. 2013 Jul;258(1):141-51. doi: 10.1097/SLA.0b013e31828cd008.

PMID:
23532108
3.

GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.

Tan MC, Basturk O, Brannon AR, Bhanot U, Scott SN, Bouvier N, LaFemina J, Jarnagin WR, Berger MF, Klimstra D, Allen PJ.

J Am Coll Surg. 2015 May;220(5):845-54.e1. doi: 10.1016/j.jamcollsurg.2014.11.029. Epub 2015 Feb 11.

PMID:
25840541
4.

GNAS mutation is a frequent event in pancreatic intraductal papillary mucinous neoplasms and associated adenocarcinomas.

Hosoda W, Sasaki E, Murakami Y, Yamao K, Shimizu Y, Yatabe Y.

Virchows Arch. 2015 Jun;466(6):665-74. doi: 10.1007/s00428-015-1751-6. Epub 2015 Mar 22.

PMID:
25796395
5.

Assessment of clonality of multisegmental main duct intraductal papillary mucinous neoplasms of the pancreas based on GNAS mutation analysis.

Tamura K, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Ideno N, Aso T, Miyazaki T, Ohuchida K, Takahata S, Ito T, Ushijima Y, Oda Y, Mizumoto K, Tanaka M.

Surgery. 2015 Feb;157(2):277-84. doi: 10.1016/j.surg.2014.09.013. Epub 2014 Dec 16.

PMID:
25530484
6.

The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant.

Yamaguchi H, Kuboki Y, Hatori T, Yamamoto M, Shimizu K, Shiratori K, Shibata N, Shimizu M, Furukawa T.

J Pathol. 2013 Nov;231(3):335-41. doi: 10.1002/path.4242.

PMID:
23893889
7.

Clinical significance of GNAS mutation in intraductal papillary mucinous neoplasm of the pancreas with concomitant pancreatic ductal adenocarcinoma.

Ideno N, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Tamura K, Aso T, Aishima S, Miyasaka Y, Ohuchida K, Ueda J, Takahata S, Oda Y, Mizumoto K, Tanaka M.

Pancreas. 2015 Mar;44(2):311-20. doi: 10.1097/MPA.0000000000000258.

PMID:
25479586
8.

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.

Dal Molin M, Matthaei H, Wu J, Blackford A, Debeljak M, Rezaee N, Wolfgang CL, Butturini G, Salvia R, Bassi C, Goggins MG, Kinzler KW, Vogelstein B, Eshleman JR, Hruban RH, Maitra A.

Ann Surg Oncol. 2013 Nov;20(12):3802-8. doi: 10.1245/s10434-013-3096-1. Epub 2013 Jul 12.

9.

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.

Amato E, Molin MD, Mafficini A, Yu J, Malleo G, Rusev B, Fassan M, Antonello D, Sadakari Y, Castelli P, Zamboni G, Maitra A, Salvia R, Hruban RH, Bassi C, Capelli P, Lawlor RT, Goggins M, Scarpa A.

J Pathol. 2014 Jul;233(3):217-27. doi: 10.1002/path.4344.

10.

GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".

Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH.

Am J Surg Pathol. 2014 Mar;38(3):360-3. doi: 10.1097/PAS.0000000000000117.

11.

Preoperative GNAS and KRAS testing in the diagnosis of pancreatic mucinous cysts.

Singhi AD, Nikiforova MN, Fasanella KE, McGrath KM, Pai RK, Ohori NP, Bartholow TL, Brand RE, Chennat JS, Lu X, Papachristou GI, Slivka A, Zeh HJ, Zureikat AH, Lee KK, Tsung A, Mantha GS, Khalid A.

Clin Cancer Res. 2014 Aug 15;20(16):4381-9. doi: 10.1158/1078-0432.CCR-14-0513. Epub 2014 Jun 17.

12.

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts.

Kanda M, Knight S, Topazian M, Syngal S, Farrell J, Lee J, Kamel I, Lennon AM, Borges M, Young A, Fujiwara S, Seike J, Eshleman J, Hruban RH, Canto MI, Goggins M.

Gut. 2013 Jul;62(7):1024-33. doi: 10.1136/gutjnl-2012-302823. Epub 2012 Aug 2.

13.

A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.

Komatsu H, Tanji E, Sakata N, Aoki T, Motoi F, Naitoh T, Katayose Y, Egawa S, Unno M, Furukawa T.

PLoS One. 2014 Feb 3;9(2):e87875. doi: 10.1371/journal.pone.0087875. eCollection 2014.

14.

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.

Wu J, Matthaei H, Maitra A, Dal Molin M, Wood LD, Eshleman JR, Goggins M, Canto MI, Schulick RD, Edil BH, Wolfgang CL, Klein AP, Diaz LA Jr, Allen PJ, Schmidt CM, Kinzler KW, Papadopoulos N, Hruban RH, Vogelstein B.

Sci Transl Med. 2011 Jul 20;3(92):92ra66. doi: 10.1126/scitranslmed.3002543.

16.

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas.

Furukawa T, Kuboki Y, Tanji E, Yoshida S, Hatori T, Yamamoto M, Shibata N, Shimizu K, Kamatani N, Shiratori K.

Sci Rep. 2011;1:161. doi: 10.1038/srep00161. Epub 2011 Nov 18.

17.

Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas.

Sakamoto H, Kuboki Y, Hatori T, Yamamoto M, Sugiyama M, Shibata N, Shimizu K, Shiratori K, Furukawa T.

Mod Pathol. 2015 Feb;28(2):261-7. doi: 10.1038/modpathol.2014.98. Epub 2014 Aug 1.

18.

Not all mixed-type intraductal papillary mucinous neoplasms behave like main-duct lesions: implications of minimal involvement of the main pancreatic duct.

Sahora K, Fernández-del Castillo C, Dong F, Marchegiani G, Thayer SP, Ferrone CR, Sahani DV, Brugge WR, Warshaw AL, Lillemoe KD, Mino-Kenudson M.

Surgery. 2014 Sep;156(3):611-21. doi: 10.1016/j.surg.2014.04.023. Epub 2014 Jul 28.

PMID:
25081232
19.

Pancreatic main-duct involvement in branch-duct IPMNs: an underestimated risk.

Fritz S, Klauss M, Bergmann F, Strobel O, Schneider L, Werner J, Hackert T, B├╝chler MW.

Ann Surg. 2014 Nov;260(5):848-55; discussion 855-6. doi: 10.1097/SLA.0000000000000980.

PMID:
25379856
20.

Treatment strategy for main duct intraductal papillary mucinous neoplasms of the pancreas based on the assessment of recurrence in the remnant pancreas after resection: a retrospective review.

Tamura K, Ohtsuka T, Ideno N, Aso T, Shindo K, Aishima S, Ohuchida K, Takahata S, Ushijima Y, Ito T, Oda Y, Mizumoto K, Tanaka M.

Ann Surg. 2014 Feb;259(2):360-8. doi: 10.1097/SLA.0b013e3182a690ff.

PMID:
23989056
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