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A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.

Rodrigues TA, Alencastre IS, Francisco T, Brites P, Fransen M, Grou CP, Azevedo JE.

Mol Cell Biol. 2014 Aug;34(15):2917-28. doi: 10.1128/MCB.01727-13. Epub 2014 May 27.


A cargo-centered perspective on the PEX5 receptor-mediated peroxisomal protein import pathway.

Francisco T, Rodrigues TA, Freitas MO, Grou CP, Carvalho AF, Sá-Miranda C, Pinto MP, Azevedo JE.

J Biol Chem. 2013 Oct 4;288(40):29151-9. doi: 10.1074/jbc.M113.487140. Epub 2013 Aug 20.


Revisiting the intraperoxisomal pathway of mammalian PEX7.

Rodrigues TA, Grou CP, Azevedo JE.

Sci Rep. 2015 Jul 3;5:11806. doi: 10.1038/srep11806.


PEX5 and ubiquitin dynamics on mammalian peroxisome membranes.

Brown AI, Kim PK, Rutenberg AD.

PLoS Comput Biol. 2014 Jan;10(1):e1003426. doi: 10.1371/journal.pcbi.1003426. Epub 2014 Jan 16.


Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway.

Alencastre IS, Rodrigues TA, Grou CP, Fransen M, Sá-Miranda C, Azevedo JE.

J Biol Chem. 2009 Oct 2;284(40):27243-51. doi: 10.1074/jbc.M109.032565. Epub 2009 Jul 23.


The unique degradation pathway of the PTS2 receptor, Pex7, is dependent on the PTS receptor/coreceptor, Pex5 and Pex20.

Hagstrom D, Ma C, Guha-Polley S, Subramani S.

Mol Biol Cell. 2014 Sep 1;25(17):2634-43. doi: 10.1091/mbc.E13-12-0716. Epub 2014 Jul 9.


PEX5, the shuttling import receptor for peroxisomal matrix proteins, is a redox-sensitive protein.

Apanasets O, Grou CP, Van Veldhoven PP, Brees C, Wang B, Nordgren M, Dodt G, Azevedo JE, Fransen M.

Traffic. 2014 Jan;15(1):94-103. doi: 10.1111/tra.12129. Epub 2013 Oct 31.


Ubiquitin in the peroxisomal protein import pathway.

Francisco T, Rodrigues TA, Pinto MP, Carvalho AF, Azevedo JE, Grou CP.

Biochimie. 2014 Mar;98:29-35. doi: 10.1016/j.biochi.2013.08.003. Epub 2013 Aug 14. Review.


Novel proteins interacting with peroxisomal protein receptor PEX7 in Arabidopsis thaliana.

Cui S, Mano S, Yamada K, Hayashi M, Nishimura M.

Plant Signal Behav. 2013 Oct;8(10):doi: 10.4161/psb.26829.


Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7.

Kunze M, Malkani N, Maurer-Stroh S, Wiesinger C, Schmid JA, Berger J.

J Biol Chem. 2015 Feb 20;290(8):4928-40. doi: 10.1074/jbc.M114.601575. Epub 2014 Dec 23.


In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes.

Miyata N, Hosoi K, Mukai S, Fujiki Y.

Biochim Biophys Acta. 2009 May;1793(5):860-70. doi: 10.1016/j.bbamcr.2009.02.007. Epub 2009 Mar 2.


Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes.

Lanyon-Hogg T, Warriner SL, Baker A.

Biol Cell. 2010 Feb 12;102(4):245-63. doi: 10.1042/BC20090159. Review.


Redox-regulated cargo binding and release by the peroxisomal targeting signal receptor, Pex5.

Ma C, Hagstrom D, Polley SG, Subramani S.

J Biol Chem. 2013 Sep 20;288(38):27220-31. doi: 10.1074/jbc.M113.492694. Epub 2013 Jul 31.


The peroxisomal protein import machinery displays a preference for monomeric substrates.

Freitas MO, Francisco T, Rodrigues TA, Lismont C, Domingues P, Pinto MP, Grou CP, Fransen M, Azevedo JE.

Open Biol. 2015 Apr;5(4):140236. doi: 10.1098/rsob.140236.


AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase.

Miyata N, Okumoto K, Mukai S, Noguchi M, Fujiki Y.

Traffic. 2012 Jan;13(1):168-83. doi: 10.1111/j.1600-0854.2011.01298.x. Epub 2011 Nov 9.


A novel Pex14 protein-interacting site of human Pex5 is critical for matrix protein import into peroxisomes.

Neuhaus A, Kooshapur H, Wolf J, Meyer NH, Madl T, Saidowsky J, Hambruch E, Lazam A, Jung M, Sattler M, Schliebs W, Erdmann R.

J Biol Chem. 2014 Jan 3;289(1):437-48. doi: 10.1074/jbc.M113.499707. Epub 2013 Nov 14.


PEX7 and EBP50 target iNOS to the peroxisome in hepatocytes.

Loughran PA, Stolz DB, Barrick SR, Wheeler DS, Friedman PA, Rachubinski RA, Watkins SC, Billiar TR.

Nitric Oxide. 2013 May 31;31:9-19. doi: 10.1016/j.niox.2013.02.084. Epub 2013 Mar 5.

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