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Results: 1 to 20 of 101

1.

ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis.

He Y, Zhang H, Yung A, Villeda SA, Jaeger PA, Olayiwola O, Fainberg N, Wyss-Coray T.

Nat Neurosci. 2014 Jul;17(7):943-52. doi: 10.1038/nn.3732. Epub 2014 May 25.

PMID:
24859199
[PubMed - in process]
2.

Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function.

Schniewind B, Groth S, Sebens Müerköster S, Sipos B, Schäfer H, Kalthoff H, Fändrich F, Ungefroren H.

Oncogene. 2007 Jul 19;26(33):4850-62. Epub 2007 Feb 12.

PMID:
17297450
[PubMed - indexed for MEDLINE]
3.

TGF-β superfamily gene expression and induction of the Runx1 transcription factor in adult neurogenic regions after brain injury.

Logan TT, Villapol S, Symes AJ.

PLoS One. 2013;8(3):e59250. doi: 10.1371/journal.pone.0059250. Epub 2013 Mar 21.

PMID:
23555640
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta.

Ungefroren H, Groth S, Ruhnke M, Kalthoff H, Fändrich F.

J Biol Chem. 2005 Jan 28;280(4):2644-52. Epub 2004 Nov 16.

PMID:
15546867
[PubMed - indexed for MEDLINE]
Free Article
5.

Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain.

Ronaldson PT, Demarco KM, Sanchez-Covarrubias L, Solinsky CM, Davis TP.

J Cereb Blood Flow Metab. 2009 Jun;29(6):1084-98. doi: 10.1038/jcbfm.2009.32. Epub 2009 Mar 25.

PMID:
19319146
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.

Yoo YA, Kang MH, Kim JS, Oh SC.

Carcinogenesis. 2008 Mar;29(3):480-90. doi: 10.1093/carcin/bgm281. Epub 2008 Jan 3.

PMID:
18174246
[PubMed - indexed for MEDLINE]
Free Article
7.

Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus.

Battista D, Ferrari CC, Gage FH, Pitossi FJ.

Eur J Neurosci. 2006 Jan;23(1):83-93.

PMID:
16420418
[PubMed - indexed for MEDLINE]
8.

Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.

Karlsson G, Liu Y, Larsson J, Goumans MJ, Lee JS, Thorgeirsson SS, Ringnér M, Karlsson S.

Physiol Genomics. 2005 May 11;21(3):396-403. Epub 2005 Mar 15.

PMID:
15769904
[PubMed - indexed for MEDLINE]
Free Article
9.

Chronic expression of transforming growth factor-beta enhances adult neurogenesis.

Mathieu P, Piantanida AP, Pitossi F.

Neuroimmunomodulation. 2010;17(3):200-1. doi: 10.1159/000258723. Epub 2010 Feb 4.

PMID:
20134202
[PubMed - indexed for MEDLINE]
10.

Age-dependent role for ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrus.

Darcy MJ, Trouche S, Jin SX, Feig LA.

Hippocampus. 2013 Oct 31. doi: 10.1002/hipo.22225. [Epub ahead of print]

PMID:
24174283
[PubMed - as supplied by publisher]
11.

Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development.

Matsunobu T, Torigoe K, Ishikawa M, de Vega S, Kulkarni AB, Iwamoto Y, Yamada Y.

Dev Biol. 2009 Aug 15;332(2):325-38. doi: 10.1016/j.ydbio.2009.06.002. Epub 2009 Jun 6.

PMID:
19501582
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.

Mazerbourg S, Klein C, Roh J, Kaivo-Oja N, Mottershead DG, Korchynskyi O, Ritvos O, Hsueh AJ.

Mol Endocrinol. 2004 Mar;18(3):653-65. Epub 2003 Dec 18.

PMID:
14684852
[PubMed - indexed for MEDLINE]
13.

TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling.

König HG, Kögel D, Rami A, Prehn JH.

J Cell Biol. 2005 Mar 28;168(7):1077-86. Epub 2005 Mar 21.

PMID:
15781474
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis.

Medina C, Santos-Martinez MJ, Santana A, Paz-Cabrera MC, Johnston MJ, Mourelle M, Salas A, Guarner F.

J Pathol. 2011 Aug;224(4):461-72. doi: 10.1002/path.2870. Epub 2011 Apr 4.

PMID:
21465486
[PubMed - indexed for MEDLINE]
15.

Transforming growth factor-beta1 causes pulmonary microvascular endothelial cell apoptosis via ALK5.

Lu Q, Patel B, Harrington EO, Rounds S.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L825-38. doi: 10.1152/ajplung.90307.2008. Epub 2009 Mar 6.

PMID:
19270180
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.

Finnson KW, Parker WL, ten Dijke P, Thorikay M, Philip A.

J Bone Miner Res. 2008 Jun;23(6):896-906. doi: 10.1359/jbmr.080209.

PMID:
18333754
[PubMed - indexed for MEDLINE]
17.

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.

Itoh F, Itoh S, Carvalho RL, Adachi T, Ema M, Goumans MJ, Larsson J, Karlsson S, Takahashi S, Mummery CL, Dijke PT, Kato M.

Lab Invest. 2009 Jul;89(7):800-10. doi: 10.1038/labinvest.2009.37. Epub 2009 Apr 27.

PMID:
19398960
[PubMed - indexed for MEDLINE]
Free Article
18.

Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses.

Itoh S, Thorikay M, Kowanetz M, Moustakas A, Itoh F, Heldin CH, ten Dijke P.

J Biol Chem. 2003 Feb 7;278(6):3751-61. Epub 2002 Nov 22.

PMID:
12446693
[PubMed - indexed for MEDLINE]
Free Article
19.

Zinc deficiency regulates hippocampal gene expression and impairs neuronal differentiation.

Gower-Winter SD, Corniola RS, Morgan TJ Jr, Levenson CW.

Nutr Neurosci. 2013 Jul;16(4):174-82. doi: 10.1179/1476830512Y.0000000043.

PMID:
23582512
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition.

Baldwin RL, Friess H, Yokoyama M, Lopez ME, Kobrin MS, Büchler MW, Korc M.

Int J Cancer. 1996 Jul 17;67(2):283-8.

PMID:
8760600
[PubMed - indexed for MEDLINE]

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