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Results: 1 to 20 of 95

1.

The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.

Gromek KA, Suchy FP, Meddaugh HR, Wrobel RL, LaPointe LM, Chu UB, Primm JG, Ruoho AE, Senes A, Fox BG.

J Biol Chem. 2014 Jul 18;289(29):20333-44. doi: 10.1074/jbc.M113.537993. Epub 2014 May 20.

PMID:
24847081
[PubMed - in process]
Free PMC Article
2.

Expression of sigma 1 receptor in human breast cancer.

Wang B, Rouzier R, Albarracin CT, Sahin A, Wagner P, Yang Y, Smith TL, Meric-Bernstam F, Marcelo Aldaz C, Hortobagyi GN, Pusztai L.

Breast Cancer Res Treat. 2004 Oct;87(3):205-14. Erratum in: Breast Cancer Res Treat. 2005 Jan;89(1):95. Marcelo, AC [corrected to Marcelo Aldaz, C].

PMID:
15528963
[PubMed - indexed for MEDLINE]
3.

Sigma 1 Receptor plays a prominent role in IL-24-induced cancer-specific apoptosis.

Do W, Herrera C, Mighty J, Shumskaya M, Redenti SM, Sauane M.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):215-20. doi: 10.1016/j.bbrc.2013.08.057. Epub 2013 Aug 26.

PMID:
23988449
[PubMed - indexed for MEDLINE]
4.

Characterization of the human sigma-1 receptor chaperone domain structure and binding immunoglobulin protein (BiP) interactions.

Ortega-Roldan JL, Ossa F, Schnell JR.

J Biol Chem. 2013 Jul 19;288(29):21448-57. doi: 10.1074/jbc.M113.450379. Epub 2013 Jun 12.

PMID:
23760505
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Oligomerization, biogenesis, and signaling is promoted by a glycophorin A-like dimerization motif in transmembrane domain 1 of a yeast G protein-coupled receptor.

Overton MC, Chinault SL, Blumer KJ.

J Biol Chem. 2003 Dec 5;278(49):49369-77. Epub 2003 Sep 23.

PMID:
14506226
[PubMed - indexed for MEDLINE]
Free Article
6.

A trimerizing GxxxG motif is uniquely inserted in the severe acute respiratory syndrome (SARS) coronavirus spike protein transmembrane domain.

Arbely E, Granot Z, Kass I, Orly J, Arkin IT.

Biochemistry. 2006 Sep 26;45(38):11349-56.

PMID:
16981695
[PubMed - indexed for MEDLINE]
7.

Multiple pathways of sigma(1) receptor ligand uptakes into primary cultured neuronal cells.

Yamamoto H, Karasawa J, Sagi N, Takahashi S, Horikomi K, Okuyama S, Nukada T, Sora I, Yamamoto T.

Eur J Pharmacol. 2001 Aug 3;425(1):1-9.

PMID:
11672569
[PubMed - indexed for MEDLINE]
8.

Improved expression and purification of sigma 1 receptor fused to maltose binding protein by alteration of linker sequence.

Gromek KA, Meddaugh HR, Wrobel RL, Suchy FP, Bingman CA, Primm JG, Fox BG.

Protein Expr Purif. 2013 Jun;89(2):203-9. doi: 10.1016/j.pep.2013.03.013. Epub 2013 Apr 3.

PMID:
23562661
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Differentiation of sigma ligand-activated receptor subtypes that modulate NMDA-evoked [3H]-noradrenaline release in rat hippocampal slices.

Monnet FP, de Costa BR, Bowen WD.

Br J Pharmacol. 1996 Sep;119(1):65-72.

PMID:
8872358
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.

Ramamoorthy JD, Ramamoorthy S, Mahesh VB, Leibach FH, Ganapathy V.

Endocrinology. 1995 Mar;136(3):924-32.

PMID:
7867601
[PubMed - indexed for MEDLINE]
11.

Development of the sigma-1 receptor in C-terminals of motoneurons and colocalization with the N,N'-dimethyltryptamine forming enzyme, indole-N-methyl transferase.

Mavlyutov TA, Epstein ML, Liu P, Verbny YI, Ziskind-Conhaim L, Ruoho AE.

Neuroscience. 2012 Mar 29;206:60-8. doi: 10.1016/j.neuroscience.2011.12.040. Epub 2012 Jan 4.

PMID:
22265729
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Cloning and functional characterization of a sigma receptor from rat brain.

Seth P, Fei YJ, Li HW, Huang W, Leibach FH, Ganapathy V.

J Neurochem. 1998 Mar;70(3):922-31.

PMID:
9489711
[PubMed - indexed for MEDLINE]
13.

Characterization of ligand binding to the σ(1) receptor in a human tumor cell line (RPMI 8226) and establishment of a competitive receptor binding assay.

Brune S, Schepmann D, Lehmkuhl K, Frehland B, Wünsch B.

Assay Drug Dev Technol. 2012 Aug;10(4):365-74. doi: 10.1089/adt.2011.0376. Epub 2011 Dec 22.

PMID:
22192304
[PubMed - indexed for MEDLINE]
14.

A-Current down-modulated by sigma receptor in frog pituitary melanotrope cells through a G protein-dependent pathway.

Soriani O, Foll FL, Roman F, Monnet FP, Vaudry H, Cazin L.

J Pharmacol Exp Ther. 1999 Apr;289(1):321-8.

PMID:
10087020
[PubMed - indexed for MEDLINE]
Free Article
15.

Lack of sigma-1 receptor exacerbates ALS progression in mice.

Mavlyutov TA, Epstein ML, Verbny YI, Huerta MS, Zaitoun I, Ziskind-Conhaim L, Ruoho AE.

Neuroscience. 2013 Jun 14;240:129-34. doi: 10.1016/j.neuroscience.2013.02.035. Epub 2013 Feb 28.

PMID:
23458708
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Expression of σ receptors of human urinary bladder tumor cells (RT-4 cells) and development of a competitive receptor binding assay for the determination of ligand affinity to human σ(2) receptors.

Schepmann D, Lehmkuhl K, Brune S, Wünsch B.

J Pharm Biomed Anal. 2011 Jul 15;55(5):1136-41. doi: 10.1016/j.jpba.2011.03.044. Epub 2011 Apr 8.

PMID:
21550749
[PubMed - indexed for MEDLINE]
17.

The effects of sigma ligands on protein release from lacrimal acinar cells: a potential agonist/antagonist assay.

Schoenwald RD, Barfknecht CF, Shirolkar S, Xia E.

Life Sci. 1995 Mar 3;56(15):1275-85.

PMID:
8614245
[PubMed - indexed for MEDLINE]
18.

Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the sigma-1 receptor.

Pal A, Chu UB, Ramachandran S, Grawoig D, Guo LW, Hajipour AR, Ruoho AE.

J Biol Chem. 2008 Jul 11;283(28):19646-56. doi: 10.1074/jbc.M802192200. Epub 2008 May 7.

PMID:
18467334
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Multiple affinity binding states of the sigma receptor: effect of GTP-binding protein-modifying agents.

Itzhak Y.

Mol Pharmacol. 1989 Oct;36(4):512-7.

PMID:
2554109
[PubMed - indexed for MEDLINE]
20.

Ionic zinc may function as an endogenous ligand for the haloperidol-sensitive sigma 2 receptor in rat brain.

Connor MA, Chavkin C.

Mol Pharmacol. 1992 Sep;42(3):471-9.

PMID:
1406599
[PubMed - indexed for MEDLINE]

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