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Results: 1 to 20 of 104

1.

DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.

Ashley AK, Shrivastav M, Nie J, Amerin C, Troksa K, Glanzer JG, Liu S, Opiyo SO, Dimitrova DD, Le P, Sishc B, Bailey SM, Oakley GG, Nickoloff JA.

DNA Repair (Amst). 2014 Sep;21:131-9. doi: 10.1016/j.dnarep.2014.04.008. Epub 2014 May 10.

PMID:
24819595
[PubMed - in process]
2.

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.

Liu S, Opiyo SO, Manthey K, Glanzer JG, Ashley AK, Amerin C, Troksa K, Shrivastav M, Nickoloff JA, Oakley GG.

Nucleic Acids Res. 2012 Nov;40(21):10780-94. doi: 10.1093/nar/gks849. Epub 2012 Sep 12.

PMID:
22977173
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

The ATR Signaling Pathway Is Disabled during Infection with the Parvovirus Minute Virus of Mice.

Adeyemi RO, Pintel DJ.

J Virol. 2014 Sep 1;88(17):10189-99. doi: 10.1128/JVI.01412-14. Epub 2014 Jun 25.

PMID:
24965470
[PubMed - in process]
5.

DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair.

Serrano MA, Li Z, Dangeti M, Musich PR, Patrick S, Roginskaya M, Cartwright B, Zou Y.

Oncogene. 2013 May 9;32(19):2452-62. doi: 10.1038/onc.2012.257. Epub 2012 Jul 16.

PMID:
22797063
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Phosphorylation of replication protein A by S-phase checkpoint kinases.

Liu JS, Kuo SR, Melendy T.

DNA Repair (Amst). 2006 Mar 7;5(3):369-80. Epub 2006 Jan 18.

PMID:
16412704
[PubMed - indexed for MEDLINE]
7.

Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.

Wang H, Guan J, Wang H, Perrault AR, Wang Y, Iliakis G.

Cancer Res. 2001 Dec 1;61(23):8554-63.

PMID:
11731442
[PubMed - indexed for MEDLINE]
Free Article
8.

Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.

Shiotani B, Nguyen HD, Håkansson P, Maréchal A, Tse A, Tahara H, Zou L.

Cell Rep. 2013 May 30;3(5):1651-62. doi: 10.1016/j.celrep.2013.04.018. Epub 2013 May 16.

PMID:
23684611
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

DNA replication defects, spontaneous DNA damage, and ATM-dependent checkpoint activation in replication protein A-deficient cells.

Dodson GE, Shi Y, Tibbetts RS.

J Biol Chem. 2004 Aug 6;279(32):34010-4. Epub 2004 Jun 14.

PMID:
15197179
[PubMed - indexed for MEDLINE]
Free Article
10.

Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress.

Feng J, Wakeman T, Yong S, Wu X, Kornbluth S, Wang XF.

Mol Cell Biol. 2009 Nov;29(21):5696-709. doi: 10.1128/MCB.00191-09. Epub 2009 Aug 24.

PMID:
19704001
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Implication of RPA32 phosphorylation in S-phase checkpoint signalling at replication forks stalled with aphidicolin in Xenopus egg extracts.

Recolin B, Maiorano D.

Biochem Biophys Res Commun. 2012 Nov 2;427(4):785-9. doi: 10.1016/j.bbrc.2012.09.139. Epub 2012 Oct 6.

PMID:
23047005
[PubMed - indexed for MEDLINE]
12.

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.

Willis J, Patel Y, Lentz BL, Yan S.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10592-7. doi: 10.1073/pnas.1301445110. Epub 2013 Jun 10.

PMID:
23754435
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.

Choi JH, Lindsey-Boltz LA, Kemp M, Mason AC, Wold MS, Sancar A.

Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13660-5. doi: 10.1073/pnas.1007856107. Epub 2010 Jun 28.

PMID:
20616048
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ATR and H2AX cooperate in maintaining genome stability under replication stress.

Chanoux RA, Yin B, Urtishak KA, Asare A, Bassing CH, Brown EJ.

J Biol Chem. 2009 Feb 27;284(9):5994-6003. doi: 10.1074/jbc.M806739200. Epub 2008 Dec 2.

PMID:
19049966
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes.

Shao RG, Cao CX, Zhang H, Kohn KW, Wold MS, Pommier Y.

EMBO J. 1999 Mar 1;18(5):1397-406.

PMID:
10064605
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

DNA-PKcs is required to maintain stability of Chk1 and Claspin for optimal replication stress response.

Lin YF, Shih HY, Shang Z, Matsunaga S, Chen BP.

Nucleic Acids Res. 2014 Apr;42(7):4463-73. doi: 10.1093/nar/gku116. Epub 2014 Feb 5.

PMID:
24500207
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

ATR phosphorylates SMARCAL1 to prevent replication fork collapse.

Couch FB, Bansbach CE, Driscoll R, Luzwick JW, Glick GG, Bétous R, Carroll CM, Jung SY, Qin J, Cimprich KA, Cortez D.

Genes Dev. 2013 Jul 15;27(14):1610-23. doi: 10.1101/gad.214080.113.

PMID:
23873943
[PubMed - indexed for MEDLINE]
Free PMC Article
18.
19.

Damage-induced phosphorylation of Sld3 is important to block late origin firing.

Lopez-Mosqueda J, Maas NL, Jonsson ZO, Defazio-Eli LG, Wohlschlegel J, Toczyski DP.

Nature. 2010 Sep 23;467(7314):479-83. doi: 10.1038/nature09377.

PMID:
20865002
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts.

Smith-Roe SL, Patel SS, Zhou Y, Simpson DA, Rao S, Ibrahim JG, Cordeiro-Stone M, Kaufmann WK.

Cell Cycle. 2013 Jan 15;12(2):332-45. doi: 10.4161/cc.23177. Epub 2012 Jan 15.

PMID:
23255133
[PubMed - indexed for MEDLINE]
Free PMC Article

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