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Items: 1 to 20 of 136

1.

Treatment with the NK1 antagonist emend reduces blood brain barrier dysfunction and edema formation in an experimental model of brain tumors.

Harford-Wright E, Lewis KM, Ghabriel MN, Vink R.

PLoS One. 2014 May 12;9(5):e97002. doi: 10.1371/journal.pone.0097002. eCollection 2014.

2.

Evaluating the role of substance P in the growth of brain tumors.

Harford-Wright E, Lewis KM, Vink R, Ghabriel MN.

Neuroscience. 2014 Mar 7;261:85-94. doi: 10.1016/j.neuroscience.2013.12.027. Epub 2013 Dec 27.

PMID:
24374326
3.

NK1 receptor blockade is ineffective in improving outcome following a balloon compression model of spinal cord injury.

Leonard AV, Thornton E, Vink R.

PLoS One. 2014 May 23;9(5):e98364. doi: 10.1371/journal.pone.0098364. eCollection 2014.

4.

Targeting classical but not neurogenic inflammation reduces peritumoral oedema in secondary brain tumours.

Lewis KM, Harford-Wright E, Vink R, Ghabriel MN.

J Neuroimmunol. 2012 Sep 15;250(1-2):59-65. doi: 10.1016/j.jneuroim.2012.06.001. Epub 2012 Jun 20.

PMID:
22722013
5.

NK1 receptor antagonists and dexamethasone as anticancer agents in vitro and in a model of brain tumours secondary to breast cancer.

Lewis KM, Harford-Wright E, Vink R, Ghabriel MN.

Anticancer Drugs. 2013 Apr;24(4):344-54. doi: 10.1097/CAD.0b013e32835ef440.

PMID:
23407059
6.

A substance P antagonist improves outcome when administered 4 h after onset of ischaemic stroke.

Turner RJ, Helps SC, Thornton E, Vink R.

Brain Res. 2011 Jun 1;1393:84-90. doi: 10.1016/j.brainres.2011.03.066. Epub 2011 Apr 3.

PMID:
21466790
7.

The effect of an NK1 receptor antagonist on blood spinal cord barrier permeability following balloon compression-induced spinal cord injury.

Leonard AV, Vink R.

Acta Neurochir Suppl. 2013;118:303-6. doi: 10.1007/978-3-7091-1434-6_59.

PMID:
23564154
8.

Substance P antagonists as a novel intervention for brain edema and raised intracranial pressure.

Gabrielian L, Helps SC, Thornton E, Turner RJ, Leonard AV, Vink R.

Acta Neurochir Suppl. 2013;118:201-4. doi: 10.1007/978-3-7091-1434-6_37. Review.

PMID:
23564132
9.

The potential for substance P antagonists as anti-cancer agents in brain tumours.

Harford-Wright E, Lewis KM, Vink R.

Recent Pat CNS Drug Discov. 2013 Apr;8(1):13-23. Review.

PMID:
23477306
10.

Substance P is associated with the development of brain edema and functional deficits after traumatic brain injury.

Donkin JJ, Nimmo AJ, Cernak I, Blumbergs PC, Vink R.

J Cereb Blood Flow Metab. 2009 Aug;29(8):1388-98. doi: 10.1038/jcbfm.2009.63. Epub 2009 May 13.

11.
12.

NK1 tachykinin receptor treatment is superior to capsaicin pre-treatment in improving functional outcome following acute ischemic stroke.

Turner RJ, Vink R.

Neuropeptides. 2014 Oct;48(5):267-72. doi: 10.1016/j.npep.2014.07.002. Epub 2014 Jul 30.

PMID:
25151181
13.

Corticotropin-releasing factor decreases vasogenic brain edema.

Tjuvajev J, Uehara H, Desai R, Beattie B, Matei C, Zhou Y, Kreek MJ, Koutcher J, Blasberg R.

Cancer Res. 1996 Mar 15;56(6):1352-60.

14.

Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4.

Li M, Ma RN, Li LH, Qu YZ, Gao GD.

Eur J Pharmacol. 2013 Sep 5;715(1-3):189-95. doi: 10.1016/j.ejphar.2013.05.022. Epub 2013 Jun 5.

PMID:
23747593
15.

Changes in substance P and NK1 receptor immunohistochemistry following human spinal cord injury.

Leonard AV, Manavis J, Blumbergs PC, Vink R.

Spinal Cord. 2014 Jan;52(1):17-23. doi: 10.1038/sc.2013.136. Epub 2013 Nov 12.

PMID:
24216617
16.

Involvement of substance P in the development of cisplatin-induced acute and delayed pica in rats.

Yamamoto K, Asano K, Tasaka A, Ogura Y, Kim S, Ito Y, Yamatodani A.

Br J Pharmacol. 2014 Jun;171(11):2888-99. doi: 10.1111/bph.12629.

17.

Lazaroid U-74389G attenuates edema in rat brain subjected to post-ischemic reperfusion injury.

Durmaz R, Ertilav K, Akyüz F, Kanbak G, Bildirici K, Tel E.

J Neurol Sci. 2003 Nov 15;215(1-2):87-93.

PMID:
14568134
18.

Hepatoblastoma cells express truncated neurokinin-1 receptor and can be growth inhibited by aprepitant in vitro and in vivo.

Berger M, Neth O, Ilmer M, Garnier A, Salinas-Martín MV, de Agustín Asencio JC, von Schweinitz D, Kappler R, Muñoz M.

J Hepatol. 2014 May;60(5):985-94. doi: 10.1016/j.jhep.2013.12.024. Epub 2014 Jan 8.

PMID:
24412605
19.
20.

Effects of hypothermia on thrombin-induced brain edema formation.

Kawai N, Kawanishi M, Okauchi M, Nagao S.

Brain Res. 2001 Mar 23;895(1-2):50-8.

PMID:
11259759
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