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Results: 1 to 20 of 89

1.

CARF and WYL domains: ligand-binding regulators of prokaryotic defense systems.

Makarova KS, Anantharaman V, Grishin NV, Koonin EV, Aravind L.

Front Genet. 2014 Apr 30;5:102. doi: 10.3389/fgene.2014.00102. eCollection 2014.

PMID:
24817877
[PubMed]
Free PMC Article
2.

CRISPR-Cas: evolution of an RNA-based adaptive immunity system in prokaryotes.

Koonin EV, Makarova KS.

RNA Biol. 2013 May;10(5):679-86. doi: 10.4161/rna.24022. Epub 2013 Feb 25. Review.

PMID:
23439366
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems.

Makarova KS, Aravind L, Wolf YI, Koonin EV.

Biol Direct. 2011 Jul 14;6:38. doi: 10.1186/1745-6150-6-38.

PMID:
21756346
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing.

Anantharaman V, Makarova KS, Burroughs AM, Koonin EV, Aravind L.

Biol Direct. 2013 Jun 15;8:15. doi: 10.1186/1745-6150-8-15.

PMID:
23768067
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements.

Makarova KS, Wolf YI, van der Oost J, Koonin EV.

Biol Direct. 2009 Aug 25;4:29. doi: 10.1186/1745-6150-4-29.

PMID:
19706170
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Live virus-free or die: coupling of antivirus immunity and programmed suicide or dormancy in prokaryotes.

Makarova KS, Anantharaman V, Aravind L, Koonin EV.

Biol Direct. 2012 Nov 14;7:40. doi: 10.1186/1745-6150-7-40.

PMID:
23151069
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Substrate generation for endonucleases of CRISPR/cas systems.

Zoephel J, Dwarakanath S, Richter H, Plagens A, Randau L.

J Vis Exp. 2012 Sep 8;(67). pii: 4277. doi: 10.3791/4277.

PMID:
22986408
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Viral diversity threshold for adaptive immunity in prokaryotes.

Weinberger AD, Wolf YI, Lobkovsky AE, Gilmore MS, Koonin EV.

MBio. 2012 Dec 4;3(6):e00456-12. doi: 10.1128/mBio.00456-12.

PMID:
23221803
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems.

Chylinski K, Le Rhun A, Charpentier E.

RNA Biol. 2013 May;10(5):726-37. doi: 10.4161/rna.24321. Epub 2013 Apr 5.

PMID:
23563642
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system.

Lintner NG, Frankel KA, Tsutakawa SE, Alsbury DL, Copié V, Young MJ, Tainer JA, Lawrence CM.

J Mol Biol. 2011 Jan 28;405(4):939-55. doi: 10.1016/j.jmb.2010.11.019. Epub 2010 Nov 18.

PMID:
21093452
[PubMed - indexed for MEDLINE]
12.

Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B.

Maier LK, Lange SJ, Stoll B, Haas KA, Fischer S, Fischer E, Duchardt-Ferner E, Wöhnert J, Backofen R, Marchfelder A.

RNA Biol. 2013 May;10(5):865-74. doi: 10.4161/rna.24282. Epub 2013 Apr 17.

PMID:
23594992
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

CRISPR-Cas systems and RNA-guided interference.

Barrangou R.

Wiley Interdiscip Rev RNA. 2013 May-Jun;4(3):267-78. doi: 10.1002/wrna.1159. Epub 2013 Mar 20. Review.

PMID:
23520078
[PubMed - indexed for MEDLINE]
14.

Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system.

Datsenko KA, Pougach K, Tikhonov A, Wanner BL, Severinov K, Semenova E.

Nat Commun. 2012 Jul 10;3:945. doi: 10.1038/ncomms1937.

PMID:
22781758
[PubMed - indexed for MEDLINE]
15.

Conservation and variability in the structure and function of the Cas5d endoribonuclease in the CRISPR-mediated microbial immune system.

Koo Y, Ka D, Kim EJ, Suh N, Bae E.

J Mol Biol. 2013 Oct 23;425(20):3799-810. doi: 10.1016/j.jmb.2013.02.032. Epub 2013 Mar 7.

PMID:
23500492
[PubMed - indexed for MEDLINE]
16.

CRISPR interference directs strand specific spacer acquisition.

Swarts DC, Mosterd C, van Passel MW, Brouns SJ.

PLoS One. 2012;7(4):e35888. doi: 10.1371/journal.pone.0035888. Epub 2012 Apr 27.

PMID:
22558257
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli.

Sapranauskas R, Gasiunas G, Fremaux C, Barrangou R, Horvath P, Siksnys V.

Nucleic Acids Res. 2011 Nov;39(21):9275-82. doi: 10.1093/nar/gkr606. Epub 2011 Aug 3.

PMID:
21813460
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Role of CRISPR/cas system in the development of bacteriophage resistance.

Szczepankowska A.

Adv Virus Res. 2012;82:289-338. doi: 10.1016/B978-0-12-394621-8.00011-X. Review.

PMID:
22420856
[PubMed - indexed for MEDLINE]
19.

A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes.

Haft DH, Selengut J, Mongodin EF, Nelson KE.

PLoS Comput Biol. 2005 Nov;1(6):e60. Epub 2005 Nov 11.

PMID:
16292354
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes.

Al-Attar S, Westra ER, van der Oost J, Brouns SJ.

Biol Chem. 2011 Apr;392(4):277-89. doi: 10.1515/BC.2011.042. Epub 2011 Feb 7. Review.

PMID:
21294681
[PubMed - indexed for MEDLINE]

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