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Results: 1 to 20 of 100

1.

Polymers Fight HIV: Potent (Pro)Drugs Identified Through Parallel Automated Synthesis.

Zuwala K, Smith AA, Postma A, Guerrero-Sanchez C, Ruiz-Sanchis P, Melchjorsen J, Tolstrup M, Zelikin AN.

Adv Healthc Mater. 2014 May 9. doi: 10.1002/adhm.201400148. [Epub ahead of print]

PMID:
24811313
[PubMed - as supplied by publisher]
2.

Macromolecular Prodrugs of Ribavirin: Concerted Efforts of the Carrier and the Drug.

Smith AA, Wohl BM, Kryger MB, Hedemann N, Guerrero-Sanchez C, Postma A, Zelikin AN.

Adv Healthc Mater. 2014 Jan 10. doi: 10.1002/adhm.201300637. [Epub ahead of print]

PMID:
24408515
[PubMed - as supplied by publisher]
3.

Novel anticancer polymeric conjugates of activated nucleoside analogues.

Senanayake TH, Warren G, Vinogradov SV.

Bioconjug Chem. 2011 Oct 19;22(10):1983-93. doi: 10.1021/bc200173e. Epub 2011 Sep 9.

PMID:
21863885
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Polyanions--a lost chance in the fight against HIV and other virus diseases?

Lüscher-Mattli M.

Antivir Chem Chemother. 2000 Jul;11(4):249-59. Review.

PMID:
10950387
[PubMed - indexed for MEDLINE]
5.

Phosphate derivatives of AZT display enhanced selectivity of action against HIV 1 by comparison to the parent nucleoside.

McGuigan C, Nickson C, Petrik J, Karpas A.

FEBS Lett. 1992 Sep 28;310(2):171-4.

PMID:
1397268
[PubMed - indexed for MEDLINE]
Free Article
6.

Lopinavir/ritonavir: a review of its use in the management of HIV infection.

Cvetkovic RS, Goa KL.

Drugs. 2003;63(8):769-802. Review.

PMID:
12662125
[PubMed - indexed for MEDLINE]
7.

Polyvalent side chain peptide-synthetic polymer conjugates as HIV-1 entry inhibitors.

Danial M, Root MJ, Klok HA.

Biomacromolecules. 2012 May 14;13(5):1438-47. doi: 10.1021/bm300150q. Epub 2012 Apr 27.

PMID:
22455441
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release.

Etrych T, Sírová M, Starovoytova L, Ríhová B, Ulbrich K.

Mol Pharm. 2010 Aug 2;7(4):1015-26. doi: 10.1021/mp100119f.

PMID:
20518512
[PubMed - indexed for MEDLINE]
9.

Polymer therapeutics-prospects for 21st century: the end of the beginning.

Duncan R, Vicent MJ.

Adv Drug Deliv Rev. 2013 Jan;65(1):60-70. doi: 10.1016/j.addr.2012.08.012. Epub 2012 Sep 5. Review.

PMID:
22981753
[PubMed - indexed for MEDLINE]
10.

Cancer-targeted polymeric drugs.

Luo Y, Prestwich GD.

Curr Cancer Drug Targets. 2002 Sep;2(3):209-26. Review.

PMID:
12188908
[PubMed - indexed for MEDLINE]
12.

Designing polymer conjugates as lysosomotropic nanomedicines.

Duncan R.

Biochem Soc Trans. 2007 Feb;35(Pt 1):56-60. Review.

PMID:
17233601
[PubMed - indexed for MEDLINE]
13.

Poly(HEMA-Zidovudine) conjugate: a macromolecular pro-drug for improvement in the biopharmaceutical properties of the drug.

Neeraj A, Chandrasekar MJ, Sara UV, Rohini A.

Drug Deliv. 2011 May;18(4):272-80. doi: 10.3109/10717544.2010.536272. Epub 2010 Nov 26.

PMID:
21110710
[PubMed - indexed for MEDLINE]
14.

Targeting of antiviral drugs to T4-lymphocytes. Anti-HIV activity of neoglycoprotein-AZTMP conjugates in vitro.

Molema G, Jansen RW, Pauwels R, de Clercq E, Meijer DK.

Biochem Pharmacol. 1990 Dec 15;40(12):2603-10.

PMID:
1979734
[PubMed - indexed for MEDLINE]
15.

Design, synthesis, and biological evaluation of anti-HIV double-drugs. conjugates of HIV protease inhibitors with a reverse transcriptase inhibitor through spontaneously cleavable linkers.

Matsumoto H, Kimura T, Hamawaki T, Kumagai A, Goto T, Sano K, Hayashi Y, Kiso Y.

Bioorg Med Chem. 2001 Jun;9(6):1589-600.

PMID:
11408178
[PubMed - indexed for MEDLINE]
16.

Potent nonclassical nucleoside antiviral drugs based on the N,N-diarylformamidine concept.

Anastasi C, Hantz O, De Clercq E, Pannecouque C, Clayette P, Dereuddre-Bosquet N, Dormont D, Gondois-Rey F, Hirsch I, Kraus JL.

J Med Chem. 2004 Feb 26;47(5):1183-92.

PMID:
14971898
[PubMed - indexed for MEDLINE]
17.

Antiviral activity and intracellular metabolism of bis(tButylSATE) phosphotriester of beta-L-2',3'dideoxyadenosine, a potent inhibitor of HIV and HBV replication.

Placidi L, Faraj A, Loi AG, Pierra C, Egron D, Cretton-Scott E, Gosseli G, Périgaud C, Martin LT, Schinazi RF, Imbach JL, el Kouni MH, Bryant ML, Sommadossi JP.

Antivir Chem Chemother. 2001 Mar;12(2):99-108.

PMID:
11527047
[PubMed - indexed for MEDLINE]
18.

Hyperbranched polymer-drug conjugates with high drug payload for enhanced cellular delivery.

Kolhe P, Khandare J, Pillai O, Kannan S, Lieh-Lai M, Kannan R.

Pharm Res. 2004 Dec;21(12):2185-95.

PMID:
15648249
[PubMed - indexed for MEDLINE]
19.

Anti-HIV efficacy and biodistribution of nucleoside reverse transcriptase inhibitors delivered as squalenoylated prodrug nanoassemblies.

Hillaireau H, Dereuddre-Bosquet N, Skanji R, Bekkara-Aounallah F, Caron J, Lepêtre S, Argote S, Bauduin L, Yousfi R, Rogez-Kreuz C, Desmaële D, Rousseau B, Gref R, Andrieux K, Clayette P, Couvreur P.

Biomaterials. 2013 Jul;34(20):4831-8. doi: 10.1016/j.biomaterials.2013.03.022. Epub 2013 Apr 2.

PMID:
23562054
[PubMed - indexed for MEDLINE]
20.

Ester prodrugs of acyclic nucleoside thiophosphonates compared to phosphonates: synthesis, antiviral activity and decomposition study.

Roux L, Priet S, Payrot N, Weck C, Fournier M, Zoulim F, Balzarini J, Canard B, Alvarez K.

Eur J Med Chem. 2013 May;63:869-81. doi: 10.1016/j.ejmech.2013.02.039. Epub 2013 Mar 14.

PMID:
23603046
[PubMed - indexed for MEDLINE]

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