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Items: 1 to 20 of 181

1.

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling.

Philip NH, Dillon CP, Snyder AG, Fitzgerald P, Wynosky-Dolfi MA, Zwack EE, Hu B, Fitzgerald L, Mauldin EA, Copenhaver AM, Shin S, Wei L, Parker M, Zhang J, Oberst A, Green DR, Brodsky IE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7385-90. doi: 10.1073/pnas.1403252111. Epub 2014 May 5.

2.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.

3.

YopJ-induced caspase-1 activation in Yersinia-infected macrophages: independent of apoptosis, linked to necrosis, dispensable for innate host defense.

Zheng Y, Lilo S, Mena P, Bliska JB.

PLoS One. 2012;7(4):e36019. doi: 10.1371/journal.pone.0036019. Epub 2012 Apr 26.

4.

Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.

Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, Mocarski ES, Pouliot K, Chan FK, Kelliher MA, Harris PA, Bertin J, Gough PJ, Shayakhmetov DM, Goguen JD, Fitzgerald KA, Silverman N, Lien E.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7391-6. doi: 10.1073/pnas.1403477111. Epub 2014 May 5.

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7.

Catalytically active Yersinia outer protein P induces cleavage of RIP and caspase-8 at the level of the DISC independently of death receptors in dendritic cells.

Gröbner S, Adkins I, Schulz S, Richter K, Borgmann S, Wesselborg S, Ruckdeschel K, Micheau O, Autenrieth IB.

Apoptosis. 2007 Oct;12(10):1813-25.

PMID:
17624595
8.

Neutrophils are resistant to Yersinia YopJ/P-induced apoptosis and are protected from ROS-mediated cell death by the type III secretion system.

Spinner JL, Seo KS, O'Loughlin JL, Cundiff JA, Minnich SA, Bohach GA, Kobayashi SD.

PLoS One. 2010 Feb 18;5(2):e9279. doi: 10.1371/journal.pone.0009279.

9.

Cell death programs in Yersinia immunity and pathogenesis.

Philip NH, Brodsky IE.

Front Cell Infect Microbiol. 2012 Nov 30;2:149. doi: 10.3389/fcimb.2012.00149. eCollection 2012. Review.

10.

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.

Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P, Verbist KC, Brewer TL, Llambi F, Gong YN, Janke LJ, Kelliher MA, Kanneganti TD, Green DR.

Cell. 2014 May 22;157(5):1189-202. doi: 10.1016/j.cell.2014.04.018. Epub 2014 May 8.

11.

Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.

Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A, Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis S, Fitzgerald KA, Stuart L, Silverman N.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12710-5. doi: 10.1073/pnas.1008203109. Epub 2012 Jul 16.

12.

RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition.

Dondelinger Y, Aguileta MA, Goossens V, Dubuisson C, Grootjans S, Dejardin E, Vandenabeele P, Bertrand MJ.

Cell Death Differ. 2013 Oct;20(10):1381-92. doi: 10.1038/cdd.2013.94. Epub 2013 Jul 26.

13.

Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ.

Lilo S, Zheng Y, Bliska JB.

Infect Immun. 2008 Sep;76(9):3911-23. doi: 10.1128/IAI.01695-07. Epub 2008 Jun 16.

14.
15.

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

Takahashi N, Vereecke L, Bertrand MJ, Duprez L, Berger SB, Divert T, Gonçalves A, Sze M, Gilbert B, Kourula S, Goossens V, Lefebvre S, Günther C, Becker C, Bertin J, Gough PJ, Declercq W, van Loo G, Vandenabeele P.

Nature. 2014 Sep 4;513(7516):95-9. doi: 10.1038/nature13706.

PMID:
25186904
16.

The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL.

Grunert M, Gottschalk K, Kapahnke J, Gündisch S, Kieser A, Jeremias I.

Cell Death Dis. 2012 Oct 25;3:e414. doi: 10.1038/cddis.2012.154.

17.
18.

Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity.

Lu JV, Weist BM, van Raam BJ, Marro BS, Nguyen LV, Srinivas P, Bell BD, Luhrs KA, Lane TE, Salvesen GS, Walsh CM.

Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15312-7. doi: 10.1073/pnas.1102779108. Epub 2011 Aug 29.

20.

RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts.

Green DR, Oberst A, Dillon CP, Weinlich R, Salvesen GS.

Mol Cell. 2011 Oct 7;44(1):9-16. doi: 10.1016/j.molcel.2011.09.003. Review.

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