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Items: 1 to 20 of 102


Autophagy plays a protective role as an anti-oxidant system in human T cells and represents a novel strategy for induction of T-cell apoptosis.

Watanabe R, Fujii H, Shirai T, Saito S, Ishii T, Harigae H.

Eur J Immunol. 2014 Aug;44(8):2508-20. doi: 10.1002/eji.201344248. Epub 2014 Jun 16.


Canonical autophagy dependent on the class III phosphoinositide-3 kinase Vps34 is required for naive T-cell homeostasis.

Willinger T, Flavell RA.

Proc Natl Acad Sci U S A. 2012 May 29;109(22):8670-5. doi: 10.1073/pnas.1205305109. Epub 2012 May 16.


Coenzyme Q deficiency triggers mitochondria degradation by mitophagy.

Rodríguez-Hernández A, Cordero MD, Salviati L, Artuch R, Pineda M, Briones P, Gómez Izquierdo L, Cotán D, Navas P, Sánchez-Alcázar JA.

Autophagy. 2009 Jan;5(1):19-32.


Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells.

He H, Zang LH, Feng YS, Chen LX, Kang N, Tashiro S, Onodera S, Qiu F, Ikejima T.

J Ethnopharmacol. 2013 Jul 9;148(2):544-55. doi: 10.1016/j.jep.2013.04.051. Epub 2013 May 14.


Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.

Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB.

J Cell Sci. 2007 Dec 1;120(Pt 23):4155-66.


Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species.

Park SH, Kim JH, Chi GY, Kim GY, Chang YC, Moon SK, Nam SW, Kim WJ, Yoo YH, Choi YH.

Toxicol Lett. 2012 Aug 3;212(3):252-61. doi: 10.1016/j.toxlet.2012.06.007. Epub 2012 Jun 18.


BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.

Kim Y, Kim YS, Kim DE, Lee JS, Song JH, Kim HG, Cho DH, Jeong SY, Jin DH, Jang SJ, Seol HS, Suh YA, Lee SJ, Kim CS, Koh JY, Hwang JJ.

Autophagy. 2013 Dec;9(12):2126-39. doi: 10.4161/auto.26308.


Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation.

Lee SJ, Ryter SW, Xu JF, Nakahira K, Kim HP, Choi AM, Kim YS.

Am J Respir Cell Mol Biol. 2011 Oct;45(4):867-73. doi: 10.1165/rcmb.2010-0352OC. Epub 2011 Mar 25.


Timosaponin A-III induces autophagy preceding mitochondria-mediated apoptosis in HeLa cancer cells.

Sy LK, Yan SC, Lok CN, Man RY, Che CM.

Cancer Res. 2008 Dec 15;68(24):10229-37. doi: 10.1158/0008-5472.CAN-08-1983.


Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

Chen Y, Gibson SB.

Autophagy. 2008 Feb;4(2):246-8. Epub 2007 Dec 14. Review.


Autophagy contributes to ING4-induced glioma cell death.

Gong A, Ye S, Xiong E, Guo W, Zhang Y, Peng W, Shao G, Jin J, Zhang Z, Yang J, Gao J.

Exp Cell Res. 2013 Jul 15;319(12):1714-23. doi: 10.1016/j.yexcr.2013.05.004. Epub 2013 May 14.


Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent.

Karna P, Zughaier S, Pannu V, Simmons R, Narayan S, Aneja R.

J Biol Chem. 2010 Jun 11;285(24):18737-48. doi: 10.1074/jbc.M109.091694. Epub 2010 Apr 19.


Apoptosis and autophagy in rat cerebellar granule neuron death: Role of reactive oxygen species.

Maycotte P, Guemez-Gamboa A, Moran J.

J Neurosci Res. 2010 Jan;88(1):73-85. doi: 10.1002/jnr.22168.


Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death.

Petit F, Arnoult D, Lelièvre JD, Moutouh-de Parseval L, Hance AJ, Schneider P, Corbeil J, Ameisen JC, Estaquier J.

J Biol Chem. 2002 Jan 11;277(2):1477-87. Epub 2001 Oct 31.


A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells.

Kim AD, Kang KA, Kim HS, Kim DH, Choi YH, Lee SJ, Kim HS, Hyun JW.

Cell Death Dis. 2013 Aug 1;4:e750. doi: 10.1038/cddis.2013.273.


Apolipoprotein L6, induced in atherosclerotic lesions, promotes apoptosis and blocks Beclin 1-dependent autophagy in atherosclerotic cells.

Zhaorigetu S, Yang Z, Toma I, McCaffrey TA, Hu CA.

J Biol Chem. 2011 Aug 5;286(31):27389-98. doi: 10.1074/jbc.M110.210245. Epub 2011 Jun 6.


Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts.

Cotán D, Cordero MD, Garrido-Maraver J, Oropesa-Ávila M, Rodríguez-Hernández A, Gómez Izquierdo L, De la Mata M, De Miguel M, Lorite JB, Infante ER, Jackson S, Navas P, Sánchez-Alcázar JA.

FASEB J. 2011 Aug;25(8):2669-87. doi: 10.1096/fj.10-165340. Epub 2011 May 6.


Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death.

Li C, Capan E, Zhao Y, Zhao J, Stolz D, Watkins SC, Jin S, Lu B.

J Immunol. 2006 Oct 15;177(8):5163-8.


Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression.

Ma KG, Shao ZW, Yang SH, Wang J, Wang BC, Xiong LM, Wu Q, Chen SF.

Osteoarthritis Cartilage. 2013 Dec;21(12):2030-8. doi: 10.1016/j.joca.2013.10.002. Epub 2013 Oct 10.

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