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Results: 1 to 20 of 100

1.

FR-190997, a nonpeptide bradykinin B2-receptor partial agonist, is a potent and efficacious intraocular pressure lowering agent in ocular hypertensive cynomolgus monkeys.

Sharif NA, Katoli P, Scott D, Li L, Kelly C, Xu S, Husain S, Toris C, Crosson C.

Drug Dev Res. 2014 Jun;75(4):211-23. doi: 10.1002/ddr.21174. Epub 2014 May 2.

PMID:
24796320
[PubMed - in process]
2.

Human non-pigmented ciliary epithelium bradykinin B2-receptors: receptor localization, pharmacological characterization of intracellular Ca(2+) mobilization, and prostaglandin secretion.

Sharif NA, Wang Y, Katoli P, Xu S, Kelly CR, Li L.

Curr Eye Res. 2014 Apr;39(4):378-89. doi: 10.3109/02713683.2013.816324. Epub 2013 Jul 25.

PMID:
24624903
[PubMed - in process]
3.

Cabergoline: Pharmacology, ocular hypotensive studies in multiple species, and aqueous humor dynamic modulation in the Cynomolgus monkey eyes.

Sharif NA, McLaughlin MA, Kelly CR, Katoli P, Drace C, Husain S, Crosson C, Toris C, Zhan GL, Camras C.

Exp Eye Res. 2009 Mar;88(3):386-97. doi: 10.1016/j.exer.2008.10.003. Epub 2008 Nov 1.

PMID:
18992242
[PubMed - indexed for MEDLINE]
4.

Trabecular meshwork bradykinin receptors: mRNA levels, immunohistochemical visualization, signaling processes pharmacology, and linkage to IOP reduction.

Sharif NA, Katoli P, Kelly CR, Li L, Xu S, Wang Y, Klekar L, Earnest D, Yacoub S, Hamilton G, Jacobson N, Shepard AR, Ellis D.

J Ocul Pharmacol Ther. 2014 Feb;30(1):21-34. doi: 10.1089/jop.2013.0105. Epub 2013 Nov 16.

PMID:
24236827
[PubMed - in process]
5.

Protein expression, biochemical pharmacology of signal transduction, and relation to intraocular pressure modulation by bradykinin B₂ receptors in ciliary muscle.

Sharif NA, Xu S, Li L, Katoli P, Kelly CR, Wang Y, Cao S, Patil R, Husain S, Klekar L, Scott D.

Mol Vis. 2013 Jun 15;19:1356-70. Print 2013.

PMID:
23805043
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action.

Sharif NA.

Curr Drug Targets. 2010 Aug;11(8):978-93. Review.

PMID:
20426763
[PubMed - indexed for MEDLINE]
7.

AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist.

Sharif NA, McLaughlin MA, Kelly CR.

J Ocul Pharmacol Ther. 2007 Feb;23(1):1-13.

PMID:
17341144
[PubMed - indexed for MEDLINE]
8.
9.

Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in cultured cells.

Sharif NA, Kelly CR, Crider JY, Williams GW, Xu SX.

J Ocul Pharmacol Ther. 2003 Dec;19(6):501-15.

PMID:
14733708
[PubMed - indexed for MEDLINE]
10.

Human trabecular meshwork cells express functional serotonin-2A (5HT2A) receptors: role in IOP reduction.

Sharif NA, Kelly CR, McLaughlin M.

Invest Ophthalmol Vis Sci. 2006 Sep;47(9):4001-10.

PMID:
16936116
[PubMed - indexed for MEDLINE]
Free Article
11.

Preclinical pharmacology of AL-12182, a new ocular hypotensive 11-oxa prostaglandin analog.

Sharif NA, McLaughlin MA, Kelly CR, Xu S, Crider JY, Williams GW, Parker JL.

J Ocul Pharmacol Ther. 2006 Oct;22(5):291-309.

PMID:
17076623
[PubMed - indexed for MEDLINE]
12.

The longitudinal muscle of rat ileum as a sensitive monoreceptor assay for bradykinin B1 receptors.

Meini S, Lecci A, Maggi CA.

Br J Pharmacol. 1996 Apr;117(8):1619-24.

PMID:
8732268
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The N-terminal of icatibant and bradykinin interact with the same Asp residues in the human B2 receptor.

Bellucci F, Meini S, Cucchi P, Catalani C, Giuliani S, Zappitelli S, Rotondaro L, Quartara L, Giolitti A, Maggi CA.

Eur J Pharmacol. 2004 May 3;491(2-3):121-5.

PMID:
15140628
[PubMed - indexed for MEDLINE]
14.

Pharmacological characterization of a nonpeptide bradykinin B2 receptor antagonist, FR165649, and agonist, FR190997.

Asano M, Hatori C, Sawai H, Johki S, Inamura N, Kayakiri H, Satoh S, Abe Y, Inoue T, Sawada Y, Mizutani T, Oku T, Nakahara K.

Br J Pharmacol. 1998 Jun;124(3):441-6.

PMID:
9647466
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Characterization of non-peptide bradykinin B2 receptor agonist (FR 190997) and antagonist (FR 173657).

Gobeil F Jr, Montagne M, Inamura N, Regoli D.

Immunopharmacology. 1999 Sep;43(2-3):179-85.

PMID:
10596851
[PubMed - indexed for MEDLINE]
16.

L-662,583 is a topically effective ocular hypotensive carbonic anhydrase inhibitor in experimental animals.

Sugrue MF, Gautheron P, Mallorga P, Nolan TE, Graham SL, Schwam H, Shepard KL, Smith RL.

Br J Pharmacol. 1990 Jan;99(1):59-64.

PMID:
2110013
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Molecular pharmacology of the DP/EP2 class prostaglandin AL-6598 and quantitative autoradiographic visualization of DP and EP2 receptor sites in human eyes.

Sharif NA, Williams GW, Crider JY, Xu SX, Davis TL.

J Ocul Pharmacol Ther. 2004 Dec;20(6):489-508.

PMID:
15684809
[PubMed - indexed for MEDLINE]
18.

The prostanoid EP2 receptor agonist butaprost increases uveoscleral outflow in the cynomolgus monkey.

Nilsson SF, Drecoll E, Lütjen-Drecoll E, Toris CB, Krauss AH, Kharlamb A, Nieves A, Guerra T, Woodward DF.

Invest Ophthalmol Vis Sci. 2006 Sep;47(9):4042-9.

PMID:
16936121
[PubMed - indexed for MEDLINE]
Free Article
19.
20.

Pharmacological characteristics of AFP-168 (tafluprost), a new prostanoid FP receptor agonist, as an ocular hypotensive drug.

Takagi Y, Nakajima T, Shimazaki A, Kageyama M, Matsugi T, Matsumura Y, Gabelt BT, Kaufman PL, Hara H.

Exp Eye Res. 2004 Apr;78(4):767-76.

PMID:
15037111
[PubMed - indexed for MEDLINE]

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