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Results: 1 to 20 of 102

1.

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations.

Kohsaka S, Shukla N, Ameur N, Ito T, Ng CK, Wang L, Lim D, Marchetti A, Viale A, Pirun M, Socci ND, Qin LX, Sciot R, Bridge J, Singer S, Meyers P, Wexler LH, Barr FG, Dogan S, Fletcher JA, Reis-Filho JS, Ladanyi M.

Nat Genet. 2014 Jun;46(6):595-600. doi: 10.1038/ng.2969. Epub 2014 May 4.

PMID:
24793135
[PubMed - indexed for MEDLINE]
2.

Transactivating mutation of the MYOD1 gene is a frequent event in adult spindle cell rhabdomyosarcoma.

Szuhai K, de Jong D, Leung WY, Fletcher CD, Hogendoorn PC.

J Pathol. 2014 Feb;232(3):300-7. doi: 10.1002/path.4307.

PMID:
24272621
[PubMed - indexed for MEDLINE]
3.

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma.

Zibat A, Missiaglia E, Rosenberger A, Pritchard-Jones K, Shipley J, Hahn H, Fulda S.

Oncogene. 2010 Dec 2;29(48):6323-30. doi: 10.1038/onc.2010.368. Epub 2010 Sep 6.

PMID:
20818440
[PubMed - indexed for MEDLINE]
4.

Rhabdomyosarcoma: molecular analysis of Igf2, MyoD1 and Myogenin expression.

Krskova L, Augustinakova A, Drahokoupilova E, Sumerauer D, Mudry P, Kodet R.

Neoplasma. 2011;58(5):415-23.

PMID:
21744995
[PubMed - indexed for MEDLINE]
5.

Targeting oxidative stress in embryonal rhabdomyosarcoma.

Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Cancer Cell. 2013 Dec 9;24(6):710-24. doi: 10.1016/j.ccr.2013.11.002.

PMID:
24332040
[PubMed - indexed for MEDLINE]
6.

Methylation alterations of the MyoD1 upstream region are predictive of subclassification of human rhabdomyosarcomas.

Chen B, Dias P, Jenkins JJ 3rd, Savell VH, Parham DM.

Am J Pathol. 1998 Apr;152(4):1071-9.

PMID:
9546368
[PubMed - indexed for MEDLINE]
Free PMC Article
7.
8.

Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways.

Shukla N, Ameur N, Yilmaz I, Nafa K, Lau CY, Marchetti A, Borsu L, Barr FG, Ladanyi M.

Clin Cancer Res. 2012 Feb 1;18(3):748-57. doi: 10.1158/1078-0432.CCR-11-2056. Epub 2011 Dec 5.

PMID:
22142829
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Identification of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma.

Ahn EH, Mercado GE, Laé M, Ladanyi M.

Oncol Rep. 2013 Aug;30(2):968-78. doi: 10.3892/or.2013.2513. Epub 2013 Jun 3.

PMID:
23733015
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Detection and clinical significance of bone marrow involvement in patients with rhabdomyosarcoma.

Krsková L, Mrhalová M, Hilská I, Sumerauer D, Drahokoupilová E, Múdry P, Kodet R.

Virchows Arch. 2010 May;456(5):463-72. doi: 10.1007/s00428-010-0913-9. Epub 2010 Apr 20.

PMID:
20405298
[PubMed - indexed for MEDLINE]
11.

Classification of rhabdomyosarcoma and its molecular basis.

Parham DM, Barr FG.

Adv Anat Pathol. 2013 Nov;20(6):387-97. doi: 10.1097/PAP.0b013e3182a92d0d. Review.

PMID:
24113309
[PubMed - indexed for MEDLINE]
12.

Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas.

Laé M, Ahn EH, Mercado GE, Chuai S, Edgar M, Pawel BR, Olshen A, Barr FG, Ladanyi M.

J Pathol. 2007 Jun;212(2):143-51.

PMID:
17471488
[PubMed - indexed for MEDLINE]
13.

Myc oncogene expression and nude mouse tumorigenicity and metastasis formation are higher in alveolar than embryonal rhabdomyosarcoma cell lines.

Kouraklis G, Triche TJ, Wesley R, Tsokos M.

Pediatr Res. 1999 Apr;45(4 Pt 1):552-8.

PMID:
10203148
[PubMed - indexed for MEDLINE]
14.

Regulation of target genes of PAX3-FOXO1 in alveolar rhabdomyosarcoma.

Ahn EH.

Anticancer Res. 2013 May;33(5):2029-35.

PMID:
23645752
[PubMed - indexed for MEDLINE]
15.

Are myogenin and myoD1 expression specific for rhabdomyosarcoma? A study of 150 cases, with emphasis on spindle cell mimics.

Cessna MH, Zhou H, Perkins SL, Tripp SR, Layfield L, Daines C, Coffin CM.

Am J Surg Pathol. 2001 Sep;25(9):1150-7.

PMID:
11688574
[PubMed - indexed for MEDLINE]
16.

Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes.

Bridge JA, Liu J, Qualman SJ, Suijkerbuijk R, Wenger G, Zhang J, Wan X, Baker KS, Sorensen P, Barr FG.

Genes Chromosomes Cancer. 2002 Mar;33(3):310-21.

PMID:
11807989
[PubMed - indexed for MEDLINE]
17.

A novel PAX3 rearrangement in embryonal rhabdomyosarcoma.

Hosoi H, Kakazu N, Konishi E, Tsuchihashi Y, Hada S, Amaya E, Nakabayahi Y, Misawa-Furihata A, Tabata-Maruyama H, Iehara T, Sugimoto T, Yamane H, Yamasaki M, Shiwaku K, Yanagisawa A, Ono M, Tokiwa K, Iwai N, Hashiba M, Abe T, Sawada T.

Cancer Genet Cytogenet. 2009 Mar;189(2):98-104. doi: 10.1016/j.cancergencyto.2008.10.016.

PMID:
19215790
[PubMed - indexed for MEDLINE]
18.

Recurrent t(2;2) and t(2;8) translocations in rhabdomyosarcoma without the canonical PAX-FOXO1 fuse PAX3 to members of the nuclear receptor transcriptional coactivator family.

Sumegi J, Streblow R, Frayer RW, Dal Cin P, Rosenberg A, Meloni-Ehrig A, Bridge JA.

Genes Chromosomes Cancer. 2010 Mar;49(3):224-36. doi: 10.1002/gcc.20731.

PMID:
19953635
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Myogenic regulatory protein (MyoD1) expression in childhood solid tumors: diagnostic utility in rhabdomyosarcoma.

Dias P, Parham DM, Shapiro DN, Webber BL, Houghton PJ.

Am J Pathol. 1990 Dec;137(6):1283-91.

PMID:
2260621
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

FGFR4 blockade exerts distinct antitumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma.

Crose LE, Etheridge KT, Chen C, Belyea B, Talbot LJ, Bentley RC, Linardic CM.

Clin Cancer Res. 2012 Jul 15;18(14):3780-90. doi: 10.1158/1078-0432.CCR-10-3063. Epub 2012 May 30.

PMID:
22648271
[PubMed - indexed for MEDLINE]
Free PMC Article

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