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Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis.

Zhao Z, Cheng X, Wang Y, Han R, Li L, Xiang T, He L, Long H, Zhu B, He Y.

PLoS One. 2014 Apr 30;9(4):e95884. doi: 10.1371/journal.pone.0095884. eCollection 2014.


Interleukin-6-induced epithelial-mesenchymal transition through signal transducer and activator of transcription 3 in human cervical carcinoma.

Miao JW, Liu LJ, Huang J.

Int J Oncol. 2014 Jul;45(1):165-76. doi: 10.3892/ijo.2014.2422. Epub 2014 May 6.


JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells.

Liu RY, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, Zhao J, Zhang HT.

Int J Oncol. 2014 May;44(5):1643-51. doi: 10.3892/ijo.2014.2310. Epub 2014 Feb 21.


Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance.

Kim YJ, Choi WI, Jeon BN, Choi KC, Kim K, Kim TJ, Ham J, Jang HJ, Kang KS, Ko H.

Toxicology. 2014 Aug 1;322:23-33. doi: 10.1016/j.tox.2014.04.002. Epub 2014 May 2.


37-kDa laminin receptor precursor promotes lung adenocarcinoma cell invasion and metastasis by epithelial-to-mesenchymal transition.

Wang Y, Dong H, Xu M, Xin B, Niu W, Xu D, Zhao P, Zhang B, Li Z, Liu L.

Cancer Gene Ther. 2014 Apr;21(4):150-7. doi: 10.1038/cgt.2014.10. Epub 2014 Apr 11.


Enhanced invasion of lung adenocarcinoma cells after co-culture with THP-1-derived macrophages via the induction of EMT by IL-6.

Dehai C, Bo P, Qiang T, Lihua S, Fang L, Shi J, Jingyan C, Yan Y, Guangbin W, Zhenjun Y.

Immunol Lett. 2014 Jul;160(1):1-10. doi: 10.1016/j.imlet.2014.03.004. Epub 2014 Mar 31.


Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis.

Wang H, Zhang H, Tang L, Chen H, Wu C, Zhao M, Yang Y, Chen X, Liu G.

Toxicology. 2013 Jan 7;303:139-46. doi: 10.1016/j.tox.2012.09.017. Epub 2012 Nov 9.


IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway.

Yadav A, Kumar B, Datta J, Teknos TN, Kumar P.

Mol Cancer Res. 2011 Dec;9(12):1658-67. doi: 10.1158/1541-7786.MCR-11-0271. Epub 2011 Oct 5.


Transforming growth factor-β1 promotes lung adenocarcinoma invasion and metastasis by epithelial-to-mesenchymal transition.

Zhang HJ, Wang HY, Zhang HT, Su JM, Zhu J, Wang HB, Zhou WY, Zhang H, Zhao MC, Zhang L, Chen XF.

Mol Cell Biochem. 2011 Sep;355(1-2):309-14. doi: 10.1007/s11010-011-0869-3. Epub 2011 Jun 22.


Notch3 is important for TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer bone metastasis by regulating ZEB-1.

Liu L, Chen X, Wang Y, Qu Z, Lu Q, Zhao J, Yan X, Zhang H, Zhou Y.

Cancer Gene Ther. 2014 Sep;21(9):364-72. doi: 10.1038/cgt.2014.39. Epub 2014 Aug 1.


FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.

Lu Z, Wang J, Zheng T, Liang Y, Yin D, Song R, Pei T, Pan S, Jiang H, Liu L.

BMC Cancer. 2014 Oct 25;14:783. doi: 10.1186/1471-2407-14-783.


IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer.

Kachroo P, Lee MH, Zhang L, Baratelli F, Lee G, Srivastava MK, Wang G, Walser TC, Krysan K, Sharma S, Dubinett SM, Lee JM.

J Exp Clin Cancer Res. 2013 Nov 25;32:97. doi: 10.1186/1756-9966-32-97.


N-cadherin expression is associated with acquisition of EMT phenotype and with enhanced invasion in erlotinib-resistant lung cancer cell lines.

Zhang X, Liu G, Kang Y, Dong Z, Qian Q, Ma X.

PLoS One. 2013;8(3):e57692. doi: 10.1371/journal.pone.0057692. Epub 2013 Mar 8.


Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis.

Qi HW, Xin LY, Xu X, Ji XX, Fan LH.

J Transl Med. 2014 Jan 24;12:22. doi: 10.1186/1479-5876-12-22.


MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.

Li DM, Zhang J, Li WM, Cui JT, Pan YM, Liu SQ, Xing R, Lu YY.

World J Gastroenterol. 2013 May 14;19(18):2781-92. doi: 10.3748/wjg.v19.i18.2781.


Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract.

Liu Y, Luo F, Xu Y, Wang B, Zhao Y, Xu W, Shi L, Lu X, Liu Q.

Toxicol Appl Pharmacol. 2015 Jan 1;282(1):9-19. doi: 10.1016/j.taap.2014.10.022. Epub 2014 Nov 8.


Metformin inhibits epithelial-mesenchymal transition in prostate cancer cells: involvement of the tumor suppressor miR30a and its target gene SOX4.

Zhang J, Shen C, Wang L, Ma Q, Xia P, Qi M, Yang M, Han B.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):746-52. doi: 10.1016/j.bbrc.2014.08.154. Epub 2014 Sep 6.


Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states.

Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, Uesugi M, Agoulnik S, Taylor N, Funahashi Y, Matsui J.

Br J Cancer. 2014 Mar 18;110(6):1497-505. doi: 10.1038/bjc.2014.80. Epub 2014 Feb 25.

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