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Items: 1 to 20 of 181

1.

Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.

Woodling NS, Wang Q, Priyam PG, Larkin P, Shi J, Johansson JU, Zagol-Ikapitte I, Boutaud O, Andreasson KI.

J Neurosci. 2014 Apr 23;34(17):5882-94. doi: 10.1523/JNEUROSCI.0410-14.2014.

2.

The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity.

Shi J, Johansson J, Woodling NS, Wang Q, Montine TJ, Andreasson K.

J Immunol. 2010 Jun 15;184(12):7207-18. doi: 10.4049/jimmunol.0903487. Epub 2010 May 7.

3.

Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease.

Shi J, Wang Q, Johansson JU, Liang X, Woodling NS, Priyam P, Loui TM, Merchant M, Breyer RM, Montine TJ, Andreasson K.

Ann Neurol. 2012 Nov;72(5):788-98. doi: 10.1002/ana.23677. Epub 2012 Aug 22.

4.

Loss of interleukin receptor-associated kinase 4 signaling suppresses amyloid pathology and alters microglial phenotype in a mouse model of Alzheimer's disease.

Cameron B, Tse W, Lamb R, Li X, Lamb BT, Landreth GE.

J Neurosci. 2012 Oct 24;32(43):15112-23. doi: 10.1523/JNEUROSCI.1729-12.2012.

5.

Prostaglandin signaling suppresses beneficial microglial function in Alzheimer's disease models.

Johansson JU, Woodling NS, Wang Q, Panchal M, Liang X, Trueba-Saiz A, Brown HD, Mhatre SD, Loui T, Andreasson KI.

J Clin Invest. 2015 Jan;125(1):350-64. doi: 10.1172/JCI77487. Epub 2014 Dec 8.

6.

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice.

Hickman SE, Allison EK, El Khoury J.

J Neurosci. 2008 Aug 13;28(33):8354-60. doi: 10.1523/JNEUROSCI.0616-08.2008.

7.

Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer's disease.

Cimino PJ, Yang Y, Li X, Hemingway JF, Cherne MK, Khademi SB, Fukui Y, Montine KS, Montine TJ, Keene CD.

Exp Mol Pathol. 2013 Apr;94(2):366-71. doi: 10.1016/j.yexmp.2013.01.002. Epub 2013 Jan 11.

8.

Prostaglandin E2 receptor subtype 2 regulation of scavenger receptor CD36 modulates microglial Aβ42 phagocytosis.

Li X, Melief E, Postupna N, Montine KS, Keene CD, Montine TJ.

Am J Pathol. 2015 Jan;185(1):230-9. doi: 10.1016/j.ajpath.2014.09.016. Epub 2014 Nov 15.

9.

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.

Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):6058-63. doi: 10.1073/pnas.0909586107. Epub 2010 Mar 15.

10.

Neoechinulin A suppresses amyloid-β oligomer-induced microglia activation and thereby protects PC-12 cells from inflammation-mediated toxicity.

Dewapriya P, Li YX, Himaya SW, Pangestuti R, Kim SK.

Neurotoxicology. 2013 Mar;35:30-40. doi: 10.1016/j.neuro.2012.12.004. Epub 2012 Dec 21.

PMID:
23261590
11.

Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia.

Johansson JU, Pradhan S, Lokteva LA, Woodling NS, Ko N, Brown HD, Wang Q, Loh C, Cekanaviciute E, Buckwalter M, Manning-Bog AB, Andreasson KI.

J Neurosci. 2013 Oct 2;33(40):16016-32. doi: 10.1523/JNEUROSCI.2203-13.2013.

12.

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.

Dhawan G, Combs CK.

J Neuroinflammation. 2012 Jul 2;9:117. doi: 10.1186/1742-2094-9-117.

13.

Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

Liang X, Wang Q, Hand T, Wu L, Breyer RM, Montine TJ, Andreasson K.

J Neurosci. 2005 Nov 2;25(44):10180-7.

14.

RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.

Fang F, Lue LF, Yan S, Xu H, Luddy JS, Chen D, Walker DG, Stern DM, Yan S, Schmidt AM, Chen JX, Yan SS.

FASEB J. 2010 Apr;24(4):1043-55. doi: 10.1096/fj.09-139634. Epub 2009 Nov 11.

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CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase.

Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F, Mullan M.

J Neurosci. 2000 Oct 15;20(20):7587-94.

19.

Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β.

Kauppinen TM, Suh SW, Higashi Y, Berman AE, Escartin C, Won SJ, Wang C, Cho SH, Gan L, Swanson RA.

J Neuroinflammation. 2011 Nov 3;8:152. doi: 10.1186/1742-2094-8-152.

20.

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

Lue LF, Walker DG, Brachova L, Beach TG, Rogers J, Schmidt AM, Stern DM, Yan SD.

Exp Neurol. 2001 Sep;171(1):29-45.

PMID:
11520119
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