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Results: 1 to 20 of 105

1.

New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids.

de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH.

J Biol Chem. 2014 May 30;289(22):15798-809. doi: 10.1074/jbc.M113.544346. Epub 2014 Apr 23.

PMID:
24759103
[PubMed - indexed for MEDLINE]
2.

Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling.

Truty MJ, Lomberk G, Fernandez-Zapico ME, Urrutia R.

J Biol Chem. 2009 Mar 6;284(10):6291-300. doi: 10.1074/jbc.M807791200. Epub 2008 Dec 15.

PMID:
19088080
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1.

Hayashi H, Nakagami H, Takami Y, Koriyama H, Mori M, Tamai K, Sun J, Nagao K, Morishita R, Kaneda Y.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):909-14. doi: 10.1161/ATVBAHA.108.178541. Epub 2009 Mar 26. Erratum in: Arterioscler Thromb Vasc Biol. 2009 Dec 1;29(12):e132.

PMID:
19325137
[PubMed - indexed for MEDLINE]
Free Article
4.

Low-density lipoprotein induced expression of connective tissue growth factor via transactivation of sphingosine 1-phosphate receptors in mesangial cells.

El-Shewy HM, Sohn M, Wilson P, Lee MH, Hammad SM, Luttrell LM, Jaffa AA.

Mol Endocrinol. 2012 May;26(5):833-45. doi: 10.1210/me.2011-1261. Epub 2012 Mar 15.

PMID:
22422617
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Eukaryotic elongation factor 1A interacts with sphingosine kinase and directly enhances its catalytic activity.

Leclercq TM, Moretti PA, Vadas MA, Pitson SM.

J Biol Chem. 2008 Apr 11;283(15):9606-14. doi: 10.1074/jbc.M708782200. Epub 2008 Feb 8.

PMID:
18263879
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The sphingosine kinase 1/sphingosine-1-phosphate pathway mediates COX-2 induction and PGE2 production in response to TNF-alpha.

Pettus BJ, Bielawski J, Porcelli AM, Reames DL, Johnson KR, Morrow J, Chalfant CE, Obeid LM, Hannun YA.

FASEB J. 2003 Aug;17(11):1411-21.

PMID:
12890694
[PubMed - indexed for MEDLINE]
Free Article
7.

Phospholipase C and protein kinase C-β 2 mediate insulin-like growth factor II-dependent sphingosine kinase 1 activation.

El-Shewy HM, Abdel-Samie SA, Al Qalam AM, Lee MH, Kitatani K, Anelli V, Jaffa AA, Obeid LM, Luttrell LM.

Mol Endocrinol. 2011 Dec;25(12):2144-56. doi: 10.1210/me.2011-0101. Epub 2011 Oct 20.

PMID:
22016563
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1.

Cinq-Frais C, Coatrieux C, Grazide MH, Hannun YA, Nègre-Salvayre A, Salvayre R, Augé N.

Biochim Biophys Acta. 2013 Aug;1831(8):1344-56. doi: 10.1016/j.bbalip.2013.04.014. Epub 2013 May 4.

PMID:
23651497
[PubMed - indexed for MEDLINE]
9.

Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.

Garrido-Martín EM, Blanco FJ, Roquè M, Novensà L, Tarocchi M, Lang UE, Suzuki T, Friedman SL, Botella LM, Bernabéu C.

Circ Res. 2013 Jan 4;112(1):113-27. doi: 10.1161/CIRCRESAHA.112.275586. Epub 2012 Oct 9.

PMID:
23048070
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors.

El-Shewy HM, Johnson KR, Lee MH, Jaffa AA, Obeid LM, Luttrell LM.

J Biol Chem. 2006 Oct 20;281(42):31399-407. Epub 2006 Aug 22.

PMID:
16926156
[PubMed - indexed for MEDLINE]
Free Article
11.

De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.

Berdyshev EV, Gorshkova IA, Usatyuk P, Zhao Y, Saatian B, Hubbard W, Natarajan V.

Cell Signal. 2006 Oct;18(10):1779-92. Epub 2006 Mar 10.

PMID:
16529909
[PubMed - indexed for MEDLINE]
12.

Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element.

Newberry EP, Willis D, Latifi T, Boudreaux JM, Towler DA.

Mol Endocrinol. 1997 Jul;11(8):1129-44.

PMID:
9212060
[PubMed - indexed for MEDLINE]
13.

Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids.

Yan G, Chen S, You B, Sun J.

Cardiovasc Res. 2008 May 1;78(2):308-14. doi: 10.1093/cvr/cvn006. Epub 2008 Jan 10.

PMID:
18192241
[PubMed - indexed for MEDLINE]
Free Article
14.

AP-1 regulates sphingosine kinase 1 expression in a positive feedback manner in glomerular mesangial cells exposed to high glucose.

Huang K, Huang J, Chen C, Hao J, Wang S, Huang J, Liu P, Huang H.

Cell Signal. 2014 Mar;26(3):629-38. doi: 10.1016/j.cellsig.2013.12.002. Epub 2013 Dec 14.

PMID:
24342046
[PubMed - indexed for MEDLINE]
15.

Sphingosine kinase activation regulates hepatocyte growth factor induced migration of endothelial cells.

Duan HF, Wu CT, Lu Y, Wang H, Liu HJ, Zhang QW, Jia XX, Lu ZZ, Wang LS.

Exp Cell Res. 2004 Aug 15;298(2):593-601.

PMID:
15265705
[PubMed - indexed for MEDLINE]
16.

Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate.

Siow DL, Anderson CD, Berdyshev EV, Skobeleva A, Pitson SM, Wattenberg BW.

J Lipid Res. 2010 Sep;51(9):2546-59. doi: 10.1194/jlr.M004374. Epub 2010 Apr 12.

PMID:
20386061
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells.

Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D.

Circ Res. 2008 Nov 7;103(10):1164-72. doi: 10.1161/01.RES.0000338501.84810.51. Epub 2008 Oct 10.

PMID:
18849324
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth.

Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R.

Biochem J. 2011 Apr 15;435(2):529-37. doi: 10.1042/BJ20100773.

PMID:
21171965
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells.

Gratschev D, Löf C, Heikkilä J, Björkbom A, Sukumaran P, Hinkkanen A, Slotte JP, Törnquist K.

Endocrinology. 2009 Nov;150(11):5125-34. doi: 10.1210/en.2009-0288. Epub 2009 Oct 1.

PMID:
19797403
[PubMed - indexed for MEDLINE]
20.

The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1.

Zebol JR, Hewitt NM, Moretti PA, Lynn HE, Lake JA, Li P, Vadas MA, Wattenberg BW, Pitson SM.

Int J Biochem Cell Biol. 2009 Apr;41(4):822-7. doi: 10.1016/j.biocel.2008.08.012. Epub 2008 Aug 14.

PMID:
18775504
[PubMed - indexed for MEDLINE]
Free Article
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