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Items: 1 to 20 of 102

1.

A genetically encoded aldehyde for rapid protein labelling.

Tuley A, Lee YJ, Wu B, Wang ZU, Liu WR.

Chem Commun (Camb). 2014 Jul 18;50(56):7424-6. doi: 10.1039/c4cc02000f.

2.

A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum.

Wang YS, Fang X, Wallace AL, Wu B, Liu WR.

J Am Chem Soc. 2012 Feb 15;134(6):2950-3. doi: 10.1021/ja211972x. Epub 2012 Feb 6.

3.

Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes.

Lee YJ, Kurra Y, Yang Y, Torres-Kolbus J, Deiters A, Liu WR.

Chem Commun (Camb). 2014 Nov 7;50(86):13085-8. doi: 10.1039/c4cc06435f. Erratum in: Chem Commun (Camb). 2014 Nov 11;50(87):13396.

4.

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives.

Wang YS, Russell WK, Wang Z, Wan W, Dodd LE, Pai PJ, Russell DH, Liu WR.

Mol Biosyst. 2011 Mar;7(3):714-7. doi: 10.1039/c0mb00217h. Epub 2011 Jan 14.

PMID:
21234492
5.

Expanding the genetic code of yeast for incorporation of diverse unnatural amino acids via a pyrrolysyl-tRNA synthetase/tRNA pair.

Hancock SM, Uprety R, Deiters A, Chin JW.

J Am Chem Soc. 2010 Oct 27;132(42):14819-24. doi: 10.1021/ja104609m.

6.

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.

Lang K, Davis L, Torres-Kolbus J, Chou C, Deiters A, Chin JW.

Nat Chem. 2012 Feb 5;4(4):298-304. doi: 10.1038/nchem.1250.

7.
8.

Two rapid catalyst-free click reactions for in vivo protein labeling of genetically encoded strained alkene/alkyne functionalities.

Kurra Y, Odoi KA, Lee YJ, Yang Y, Lu T, Wheeler SE, Torres-Kolbus J, Deiters A, Liu WR.

Bioconjug Chem. 2014 Sep 17;25(9):1730-8. doi: 10.1021/bc500361d. Epub 2014 Sep 4.

9.

Genetically encoded initiator for polymer growth from proteins.

Peeler JC, Woodman BF, Averick S, Miyake-Stoner SJ, Stokes AL, Hess KR, Matyjaszewski K, Mehl RA.

J Am Chem Soc. 2010 Oct 6;132(39):13575-7. doi: 10.1021/ja104493d.

PMID:
20839808
10.

The genetic incorporation of thirteen novel non-canonical amino acids.

Tuley A, Wang YS, Fang X, Kurra Y, Rezenom YH, Liu WR.

Chem Commun (Camb). 2014 Mar 11;50(20):2673-5. doi: 10.1039/c3cc49068h.

11.

Genetic incorporation of twelve meta-substituted phenylalanine derivatives using a single pyrrolysyl-tRNA synthetase mutant.

Wang YS, Fang X, Chen HY, Wu B, Wang ZU, Hilty C, Liu WR.

ACS Chem Biol. 2013 Feb 15;8(2):405-15. doi: 10.1021/cb300512r. Epub 2012 Nov 19.

12.

Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality.

Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y, Ishitani R, Umehara T, Söll D, Nureki O.

Nature. 2009 Feb 26;457(7233):1163-7. doi: 10.1038/nature07611. Epub 2008 Dec 31.

13.

Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase.

Xiao H, Peters FB, Yang PY, Reed S, Chittuluru JR, Schultz PG.

ACS Chem Biol. 2014 May 16;9(5):1092-6. doi: 10.1021/cb500032c. Epub 2014 Mar 17.

14.

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome.

Neumann H, Wang K, Davis L, Garcia-Alai M, Chin JW.

Nature. 2010 Mar 18;464(7287):441-4. doi: 10.1038/nature08817. Epub 2010 Feb 14.

PMID:
20154731
15.

A need for speed: genetic encoding of rapid cycloaddition chemistries for protein labelling in living cells.

Schmidt MJ, Summerer D.

Chembiochem. 2012 Jul 23;13(11):1553-7. doi: 10.1002/cbic.201200321. Epub 2012 Jun 29.

PMID:
22753121
16.
17.

Transforming a pair of orthogonal tRNA-aminoacyl-tRNA synthetase from Archaea to function in mammalian cells.

Thibodeaux GN, Liang X, Moncivais K, Umeda A, Singer O, Alfonta L, Zhang ZJ.

PLoS One. 2010 Jun 22;5(6):e11263. doi: 10.1371/journal.pone.0011263.

18.

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET.

Wang K, Sachdeva A, Cox DJ, Wilf NM, Lang K, Wallace S, Mehl RA, Chin JW.

Nat Chem. 2014 May;6(5):393-403. doi: 10.1038/nchem.1919. Epub 2014 Apr 20. Erratum in: Nat Chem. 2014 Feb;7(2):178. Wilf, Nabil W [corrected to Wilf, Nabil M].

19.

Recognition of non-alpha-amino substrates by pyrrolysyl-tRNA synthetase.

Kobayashi T, Yanagisawa T, Sakamoto K, Yokoyama S.

J Mol Biol. 2009 Feb 6;385(5):1352-60. doi: 10.1016/j.jmb.2008.11.059. Epub 2008 Dec 11.

PMID:
19100747
20.

A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli.

Chatterjee A, Xiao H, Yang PY, Soundararajan G, Schultz PG.

Angew Chem Int Ed Engl. 2013 May 3;52(19):5106-9. doi: 10.1002/anie.201301094. Epub 2013 Apr 2. No abstract available.

PMID:
23554007
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