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Items: 1 to 20 of 125

1.

Hemodynamic disturbed flow induces differential DNA methylation of endothelial Kruppel-Like Factor 4 promoter in vitro and in vivo.

Jiang YZ, Jiménez JM, Ou K, McCormick ME, Zhang LD, Davies PF.

Circ Res. 2014 Jun 20;115(1):32-43. doi: 10.1161/CIRCRESAHA.115.303883. Epub 2014 Apr 22.

2.

Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium.

Fang Y, Davies PF.

Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):979-87. doi: 10.1161/ATVBAHA.111.244053. Epub 2012 Jan 19.

3.

Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo.

Jiang YZ, Manduchi E, Stoeckert CJ Jr, Davies PF.

BMC Genomics. 2015 Jul 7;16:506. doi: 10.1186/s12864-015-1656-4.

4.

Histone and DNA methylation-mediated epigenetic downregulation of endothelial Kruppel-like factor 2 by low-density lipoprotein cholesterol.

Kumar A, Kumar S, Vikram A, Hoffman TA, Naqvi A, Lewarchik CM, Kim YR, Irani K.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1936-42. doi: 10.1161/ATVBAHA.113.301765. Epub 2013 May 30.

5.

Direct evidence for pitavastatin induced chromatin structure change in the KLF4 gene in endothelial cells.

Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, Kimura H, Kobayashi M, Taguchi A, Tsutsumi S, Iwanari H, Yamamoto S, Aruga H, Dong S, Stevens JF, Poh HM, Yamamoto K, Kawamura T, Mimura I, Suehiro J, Sugiyama A, Kaneki K, Shibata H, Yoshinaka Y, Doi T, Asanuma A, Tanabe S, Tanaka T, Minami T, Hamakubo T, Sakai J, Nozaki N, Aburatani H, Nangaku M, Ruan X, Tanabe H, Ruan Y, Ihara S, Endo A, Kodama T, Wada Y.

PLoS One. 2014 May 5;9(5):e96005. doi: 10.1371/journal.pone.0096005. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99749.

6.

The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation.

Chan Y, Fish JE, D'Abreo C, Lin S, Robb GB, Teichert AM, Karantzoulis-Fegaras F, Keightley A, Steer BM, Marsden PA.

J Biol Chem. 2004 Aug 13;279(33):35087-100. Epub 2004 Jun 4.

7.

Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis.

Dunn J, Qiu H, Kim S, Jjingo D, Hoffman R, Kim CW, Jang I, Son DJ, Kim D, Pan C, Fan Y, Jordan IK, Jo H.

J Clin Invest. 2014 Jul;124(7):3187-99. doi: 10.1172/JCI74792. Epub 2014 May 27.

8.

Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.

Karpurapu M, Ranjan R, Deng J, Chung S, Lee YG, Xiao L, Nirujogi TS, Jacobson JR, Park GY, Christman JW.

PLoS One. 2014 Apr 2;9(4):e93362. doi: 10.1371/journal.pone.0093362. eCollection 2014.

9.

Kruppel-like factor 4 is a novel mediator of Kallistatin in inhibiting endothelial inflammation via increased endothelial nitric-oxide synthase expression.

Shen B, Smith RS Jr, Hsu YT, Chao L, Chao J.

J Biol Chem. 2009 Dec 18;284(51):35471-8. doi: 10.1074/jbc.M109.046813. Epub .

10.

The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.

Dunn J, Simmons R, Thabet S, Jo H.

Int J Biochem Cell Biol. 2015 Oct;67:167-76. doi: 10.1016/j.biocel.2015.05.001. Epub 2015 May 13. Review.

PMID:
25979369
11.

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo.

Davies PF, Civelek M, Fang Y, Fleming I.

Cardiovasc Res. 2013 Jul 15;99(2):315-27. doi: 10.1093/cvr/cvt101. Epub 2013 Apr 25. Review.

12.

Endothelial epigenetics in biomechanical stress: disturbed flow-mediated epigenomic plasticity in vivo and in vitro.

Jiang YZ, Manduchi E, Jiménez JM, Davies PF.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1317-26. doi: 10.1161/ATVBAHA.115.303427. Epub 2015 Apr 2. Review.

13.

Flow-Dependent Regulation of Kruppel-Like Factor 2 Is Mediated by MicroRNA-92a.

Wu W, Xiao H, Laguna-Fernandez A, Villarreal G Jr, Wang KC, Geary GG, Zhang Y, Wang WC, Huang HD, Zhou J, Li YS, Chien S, Garcia-Cardena G, Shyy JY.

Circulation. 2011 Aug 2;124(5):633-41. doi: 10.1161/CIRCULATIONAHA.110.005108. Epub 2011 Jul 18.

14.

Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension.

Shatat MA, Tian H, Zhang R, Tandon G, Hale A, Fritz JS, Zhou G, Martínez-González J, Rodríguez C, Champion HC, Jain MK, Hamik A.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):647-53. doi: 10.1165/rcmb.2013-0135OC.

15.

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces.

Wu C, Huang RT, Kuo CH, Kumar S, Kim CW, Lin YC, Chen YJ, Birukova A, Birukov KG, Dulin NO, Civelek M, Lusis AJ, Loyer X, Tedgui A, Dai G, Jo H, Fang Y.

Circ Res. 2015 Jul 31;117(4):e41-53. doi: 10.1161/CIRCRESAHA.117.306457. Epub 2015 Jun 1.

16.

p53 impairs endothelial function by transcriptionally repressing Kruppel-Like Factor 2.

Kumar A, Kim CS, Hoffman TA, Naqvi A, Dericco J, Jung SB, Lin Z, Jain MK, Irani K.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):133-41. doi: 10.1161/ATVBAHA.110.215061. Epub 2010 Oct 14.

17.

Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.

Nakahara Y, Northcott PA, Li M, Kongkham PN, Smith C, Yan H, Croul S, Ra YS, Eberhart C, Huang A, Bigner D, Grajkowska W, Van Meter T, Rutka JT, Taylor MD.

Neoplasia. 2010 Jan;12(1):20-7.

18.

Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis.

Dunn J, Thabet S, Jo H.

Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1562-9. doi: 10.1161/ATVBAHA.115.305042. Epub 2015 May 7. Review.

19.

Promoter hypermethylation of KLF4 inactivates its tumor suppressor function in cervical carcinogenesis.

Yang WT, Zheng PS.

PLoS One. 2014 Feb 14;9(2):e88827. doi: 10.1371/journal.pone.0088827. eCollection 2014.

20.

Heterogeneity of endothelial cell phenotype within and amongst conduit vessels of the swine vasculature.

Simmons GH, Padilla J, Laughlin MH.

Exp Physiol. 2012 Sep;97(9):1074-82. doi: 10.1113/expphysiol.2011.064006. Epub 2012 Apr 27.

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