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Results: 1 to 20 of 101

1.

Proteasome Inhibition-Induced Downregulation of Akt/GSK-3β Pathway Contributes to Abnormality of Tau in Hippocampal Slice.

Xie M, Shi R, Pan Y, Zeng T, Chen Q, Wang S, Liao X.

Mol Neurobiol. 2014 Dec;50(3):888-95. doi: 10.1007/s12035-014-8702-0. Epub 2014 Apr 22.

PMID:
24752588
[PubMed - in process]
2.

Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation.

Wang Y, Yang R, Gu J, Yin X, Jin N, Xie S, Wang Y, Chang H, Qian W, Shi J, Iqbal K, Gong CX, Cheng C, Liu F.

Neurobiol Aging. 2015 Jan;36(1):188-200. doi: 10.1016/j.neurobiolaging.2014.07.035. Epub 2014 Aug 1.

PMID:
25219467
[PubMed - in process]
3.

Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3β Signaling in Human Tau Transgenic Mice.

Zhang Y, Ma RH, Li XC, Zhang JY, Shi HR, Wei W, Luo DJ, Wang Q, Wang JZ, Liu GP.

Front Aging Neurosci. 2014 Jun 17;6:123. doi: 10.3389/fnagi.2014.00123. eCollection 2014.

PMID:
24987368
[PubMed]
Free PMC Article
4.
5.

Inhibition of Wnt and PI3K signaling modulates GSK-3beta activity and induces morphological changes in cortical neurons: role of tau phosphorylation.

Mercado-Gómez O, Hernández-Fonseca K, Villavicencio-Queijeiro A, Massieu L, Chimal-Monroy J, Arias C.

Neurochem Res. 2008 Aug;33(8):1599-609. doi: 10.1007/s11064-008-9714-9. Epub 2008 May 7.

PMID:
18461448
[PubMed - indexed for MEDLINE]
6.

Parkinson's disease-associated DJ-1 mutations increase abnormal phosphorylation of tau protein through Akt/GSK-3β pathways.

Wang Y, Liu W, He X, Zhou F.

J Mol Neurosci. 2013 Nov;51(3):911-8. doi: 10.1007/s12031-013-0099-0. Epub 2013 Aug 27.

PMID:
23979838
[PubMed - indexed for MEDLINE]
7.

Inhibition of glycogen synthase kinase-3β by Angelica sinensis extract decreases β-amyloid-induced neurotoxicity and tau phosphorylation in cultured cortical neurons.

Zhang Z, Zhao R, Qi J, Wen S, Tang Y, Wang D.

J Neurosci Res. 2011 Mar;89(3):437-47. doi: 10.1002/jnr.22563. Epub 2010 Dec 17.

PMID:
21259330
[PubMed - indexed for MEDLINE]
8.

Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly.

Utton MA, Vandecandelaere A, Wagner U, Reynolds CH, Gibb GM, Miller CC, Bayley PM, Anderton BH.

Biochem J. 1997 May 1;323 ( Pt 3):741-7.

PMID:
9169608
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Glycogen synthase kinase-3β regulates Tyr307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src.

Yao XQ, Zhang XX, Yin YY, Liu B, Luo DJ, Liu D, Chen NN, Ni ZF, Wang X, Wang Q, Wang JZ, Liu GP.

Biochem J. 2011 Jul 15;437(2):335-44. doi: 10.1042/BJ20110347.

PMID:
21554241
[PubMed - indexed for MEDLINE]
Free Article
10.

Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration.

Wang JZ, Grundke-Iqbal I, Iqbal K.

Eur J Neurosci. 2007 Jan;25(1):59-68.

PMID:
17241267
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Akt/protein kinase b and glycogen synthase kinase-3beta signaling pathway regulates cell migration through the NFAT1 transcription factor.

Yoeli-Lerner M, Chin YR, Hansen CK, Toker A.

Mol Cancer Res. 2009 Mar;7(3):425-32. doi: 10.1158/1541-7786.MCR-08-0342. Epub 2009 Mar 3.

PMID:
19258413
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta.

Qian W, Shi J, Yin X, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F.

J Alzheimers Dis. 2010;19(4):1221-9. doi: 10.3233/JAD-2010-1317.

PMID:
20308788
[PubMed - indexed for MEDLINE]
13.

Phosphorylation of tau protein over time in rats subjected to transient brain ischemia.

Song B, Ao Q, Wang Z, Liu W, Niu Y, Shen Q, Zuo H, Zhang X, Gong Y.

Neural Regen Res. 2013 Dec 5;8(34):3173-82. doi: 10.3969/j.issn.1673-5374.2013.34.001.

PMID:
25206638
[PubMed]
Free PMC Article
14.

17beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner.

Shi HR, Zhu LQ, Wang SH, Liu XA, Tian Q, Zhang Q, Wang Q, Wang JZ.

J Neural Transm. 2008 Jun;115(6):879-88. doi: 10.1007/s00702-008-0021-z. Epub 2008 Jan 24. Erratum in: J Neural Transm. 2010 May;117(5):679-80.

PMID:
18217188
[PubMed - indexed for MEDLINE]
15.

Ginsenoside Rd attenuates tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after transient forebrain ischemia.

Zhang X, Shi M, Ye R, Wang W, Liu X, Zhang G, Han J, Zhang Y, Wang B, Zhao J, Hui J, Xiong L, Zhao G.

Neurochem Res. 2014 Jul;39(7):1363-73. doi: 10.1007/s11064-014-1321-3. Epub 2014 May 3.

PMID:
24792734
[PubMed - in process]
16.
17.

GSK-3beta directly phosphorylates and activates MARK2/PAR-1.

Kosuga S, Tashiro E, Kajioka T, Ueki M, Shimizu Y, Imoto M.

J Biol Chem. 2005 Dec 30;280(52):42715-22. Epub 2005 Oct 28.

PMID:
16257959
[PubMed - indexed for MEDLINE]
Free Article
19.

Extracellular α-synuclein leads to microtubule destabilization via GSK-3β-dependent Tau phosphorylation in PC12 cells.

Gąssowska M, Czapski GA, Pająk B, Cieślik M, Lenkiewicz AM, Adamczyk A.

PLoS One. 2014 Apr 10;9(4):e94259. doi: 10.1371/journal.pone.0094259. eCollection 2014.

PMID:
24722055
[PubMed - in process]
Free PMC Article
20.

Cleavage of GSK-3β by calpain counteracts the inhibitory effect of Ser9 phosphorylation on GSK-3β activity induced by H₂O₂.

Feng Y, Xia Y, Yu G, Shu X, Ge H, Zeng K, Wang J, Wang X.

J Neurochem. 2013 Jul;126(2):234-42. doi: 10.1111/jnc.12285. Epub 2013 May 30.

PMID:
23646926
[PubMed - indexed for MEDLINE]

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