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Items: 1 to 20 of 107


Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and function.

Pathak N, Austin-Tse CA, Liu Y, Vasilyev A, Drummond IA.

Mol Biol Cell. 2014 Jun 15;25(12):1836-44. doi: 10.1091/mbc.E13-01-0033. Epub 2014 Apr 17.


Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility.

Pathak N, Austin CA, Drummond IA.

J Biol Chem. 2011 Apr 1;286(13):11685-95. doi: 10.1074/jbc.M110.209817. Epub 2011 Jan 24.


Zebrafish cytosolic carboxypeptidases 1 and 5 are essential for embryonic development.

Lyons PJ, Sapio MR, Fricker LD.

J Biol Chem. 2013 Oct 18;288(42):30454-62. doi: 10.1074/jbc.M113.497933. Epub 2013 Sep 10.


The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.

Pathak N, Obara T, Mangos S, Liu Y, Drummond IA.

Mol Biol Cell. 2007 Nov;18(11):4353-64. Epub 2007 Aug 29.


Glutamylation on alpha-tubulin is not essential but affects the assembly and functions of a subset of microtubules in Tetrahymena thermophila.

Wloga D, Rogowski K, Sharma N, Van Dijk J, Janke C, Eddé B, Bré MH, Levilliers N, Redeker V, Duan J, Gorovsky MA, Jerka-Dziadosz M, Gaertig J.

Eukaryot Cell. 2008 Aug;7(8):1362-72. doi: 10.1128/EC.00084-08. Epub 2008 Jun 27.


Identification of tubulin deglutamylase among Caenorhabditis elegans and mammalian cytosolic carboxypeptidases (CCPs).

Kimura Y, Kurabe N, Ikegami K, Tsutsumi K, Konishi Y, Kaplan OI, Kunitomo H, Iino Y, Blacque OE, Setou M.

J Biol Chem. 2010 Jul 23;285(30):22936-41. doi: 10.1074/jbc.C110.128280. Epub 2010 Jun 2.


TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

Wloga D, Webster DM, Rogowski K, Bré MH, Levilliers N, Jerka-Dziadosz M, Janke C, Dougan ST, Gaertig J.

Dev Cell. 2009 Jun;16(6):867-76. doi: 10.1016/j.devcel.2009.04.008.


The tubulin deglutamylase CCPP-1 regulates the function and stability of sensory cilia in C. elegans.

O'Hagan R, Piasecki BP, Silva M, Phirke P, Nguyen KC, Hall DH, Swoboda P, Barr MM.

Curr Biol. 2011 Oct 25;21(20):1685-94. doi: 10.1016/j.cub.2011.08.049. Epub 2011 Oct 6.


Hyperglutamylation of tubulin can either stabilize or destabilize microtubules in the same cell.

Wloga D, Dave D, Meagley J, Rogowski K, Jerka-Dziadosz M, Gaertig J.

Eukaryot Cell. 2010 Jan;9(1):184-93. doi: 10.1128/EC.00176-09. Epub 2009 Aug 21.


Tubulin glutamylation regulates ciliary motility by altering inner dynein arm activity.

Suryavanshi S, Eddé B, Fox LA, Guerrero S, Hard R, Hennessey T, Kabi A, Malison D, Pennock D, Sale WS, Wloga D, Gaertig J.

Curr Biol. 2010 Mar 9;20(5):435-40. doi: 10.1016/j.cub.2009.12.062.


Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish.

Zhang Q, Liu Q, Austin C, Drummond I, Pierce EA.

Mol Biol Cell. 2012 Aug;23(16):3069-78. doi: 10.1091/mbc.E12-01-0019. Epub 2012 Jun 20.


Glutamylated tubulin: diversity of expression and distribution of isoforms.

Kann ML, Soues S, Levilliers N, Fouquet JP.

Cell Motil Cytoskeleton. 2003 May;55(1):14-25.


Cytosolic carboxypeptidase 5 removes α- and γ-linked glutamates from tubulin.

Berezniuk I, Lyons PJ, Sironi JJ, Xiao H, Setou M, Angeletti RH, Ikegami K, Fricker LD.

J Biol Chem. 2013 Oct 18;288(42):30445-53. doi: 10.1074/jbc.M113.497917. Epub 2013 Sep 10.


CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium.

Lee JE, Silhavy JL, Zaki MS, Schroth J, Bielas SL, Marsh SE, Olvera J, Brancati F, Iannicelli M, Ikegami K, Schlossman AM, Merriman B, Attié-Bitach T, Logan CV, Glass IA, Cluckey A, Louie CM, Lee JH, Raynes HR, Rapin I, Castroviejo IP, Setou M, Barbot C, Boltshauser E, Nelson SF, Hildebrandt F, Johnson CA, Doherty DA, Valente EM, Gleeson JG.

Nat Genet. 2012 Jan 15;44(2):193-9. doi: 10.1038/ng.1078.


Ciliary tubulin and its post-translational modifications.

Gaertig J, Wloga D.

Curr Top Dev Biol. 2008;85:83-113. doi: 10.1016/S0070-2153(08)00804-1. Review.


Tubulin posttranslational modifications: a Pushmi-Pullyu at work?

Bulinski JC.

Dev Cell. 2009 Jun;16(6):773-4. doi: 10.1016/j.devcel.2009.06.003.


Sept6 is required for ciliogenesis in Kupffer's vesicle, the pronephros, and the neural tube during early embryonic development.

Zhai G, Gu Q, He J, Lou Q, Chen X, Jin X, Bi E, Yin Z.

Mol Cell Biol. 2014 Apr;34(7):1310-21. doi: 10.1128/MCB.01409-13. Epub 2014 Jan 27.


CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development.

Backer CB, Gutzman JH, Pearson CG, Cheeseman IM.

Mol Biol Cell. 2012 Jun;23(11):2122-30. doi: 10.1091/mbc.E11-11-0931. Epub 2012 Apr 4.


Ciliary and flagellar structure and function--their regulations by posttranslational modifications of axonemal tubulin.

Konno A, Setou M, Ikegami K.

Int Rev Cell Mol Biol. 2012;294:133-70. doi: 10.1016/B978-0-12-394305-7.00003-3. Review.

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