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Items: 1 to 20 of 96

1.

Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor-mediated kidney fibrosis.

Zhang JD, Patel MB, Griffiths R, Dolber PC, Ruiz P, Sparks MA, Stegbauer J, Jin H, Gomez JA, Buckley AF, Lefler WS, Chen D, Crowley SD.

J Clin Invest. 2014 May;124(5):2198-203. doi: 10.1172/JCI61368. Epub 2014 Apr 17.

2.

Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction.

Skuginna V, Lech M, Allam R, Ryu M, Clauss S, Susanti HE, Römmele C, Garlanda C, Mantovani A, Anders HJ.

PLoS One. 2011 Apr 22;6(4):e19204. doi: 10.1371/journal.pone.0019204.

3.

Macrophage infiltration and renal damage are independent of matrix metalloproteinase 12 in the obstructed kidney.

Abraham AP, Ma FY, Mulley WR, Ozols E, Nikolic-Paterson DJ.

Nephrology (Carlton). 2012 May;17(4):322-9. doi: 10.1111/j.1440-1797.2012.01567.x.

PMID:
22257277
4.

RAGE-mediated interstitial fibrosis in neonatal obstructive nephropathy is independent of NF-κB activation.

Gasparitsch M, Arndt AK, Pawlitschek F, Oberle S, Keller U, Kasper M, Bierhaus A, Schaefer F, Weber LT, Lange-Sperandio B.

Kidney Int. 2013 Nov;84(5):911-9. doi: 10.1038/ki.2013.171. Epub 2013 May 15.

PMID:
23677242
5.

MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages.

Braga TT, Correa-Costa M, Guise YF, Castoldi A, de Oliveira CD, Hyane MI, Cenedeze MA, Teixeira SA, Muscara MN, Perez KR, Cuccovia IM, Pacheco-Silva A, Gonçalves GM, Camara NO.

Mol Med. 2012 Oct 24;18:1231-9. doi: 10.2119/molmed.2012.00131.

6.

ASK1/p38 signaling in renal tubular epithelial cells promotes renal fibrosis in the mouse obstructed kidney.

Ma FY, Tesch GH, Nikolic-Paterson DJ.

Am J Physiol Renal Physiol. 2014 Dec 1;307(11):F1263-73. doi: 10.1152/ajprenal.00211.2014. Epub 2014 Oct 8.

7.

Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis.

Nishida M, Fujinaka H, Matsusaka T, Price J, Kon V, Fogo AB, Davidson JM, Linton MF, Fazio S, Homma T, Yoshida H, Ichikawa I.

J Clin Invest. 2002 Dec;110(12):1859-68.

8.

Exaggerated renal fibrosis in P2X4 receptor-deficient mice following unilateral ureteric obstruction.

Kim MJ, Turner CM, Hewitt R, Smith J, Bhangal G, Pusey CD, Unwin RJ, Tam FW.

Nephrol Dial Transplant. 2014 Jul;29(7):1350-61. doi: 10.1093/ndt/gfu019. Epub 2014 Feb 25.

9.

Telmisartan inhibits both oxidative stress and renal fibrosis after unilateral ureteral obstruction in acatalasemic mice.

Sugiyama H, Kobayashi M, Wang DH, Sunami R, Maeshima Y, Yamasaki Y, Masuoka N, Kira S, Makino H.

Nephrol Dial Transplant. 2005 Dec;20(12):2670-80. Epub 2005 Sep 2.

10.

Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction.

Esteban V, Lorenzo O, Rupérez M, Suzuki Y, Mezzano S, Blanco J, Kretzler M, Sugaya T, Egido J, Ruiz-Ortega M.

J Am Soc Nephrol. 2004 Jun;15(6):1514-29.

11.

Vitronectin accumulates in the interstitium but minimally impacts fibrogenesis in experimental chronic kidney disease.

López-Guisa JM, Rassa AC, Cai X, Collins SJ, Eddy AA.

Am J Physiol Renal Physiol. 2011 May;300(5):F1244-54. doi: 10.1152/ajprenal.00701.2010. Epub 2011 Jan 26.

12.

Angiotensin AT1-receptor inhibition exacerbates renal injury resulting from partial unilateral ureteral obstruction in the neonatal rat.

Coleman CM, Minor JJ, Burt LE, Thornhill BA, Forbes MS, Chevalier RL.

Am J Physiol Renal Physiol. 2007 Jul;293(1):F262-8. Epub 2007 Apr 18.

13.

Effect of angiotensin II and small GTPase Ras signaling pathway inhibition on early renal changes in a murine model of obstructive nephropathy.

Rodríguez-Peña AB, Fuentes-Calvo I, Docherty NG, Arévalo M, Grande MT, Eleno N, Pérez-Barriocanal F, López-Novoa JM.

Biomed Res Int. 2014;2014:124902. doi: 10.1155/2014/124902. Epub 2014 Jul 3.

14.

Angiotensin AT(1) receptor inhibition-induced apoptosis by RhoA GTPase activation and pERK1/2 signaling pathways in neonatal obstructive nephropathy.

Bocanegra V, Rinaldi Tosi M, Gil Lorenzo A, Cacciamani V, Manucha W, Fornés M, Vallés PG.

Histol Histopathol. 2012 Jul;27(7):919-30.

PMID:
22648547
15.

Complement C5 mediates experimental tubulointerstitial fibrosis.

Boor P, Konieczny A, Villa L, Schult AL, Bücher E, Rong S, Kunter U, van Roeyen CR, Polakowski T, Hawlisch H, Hillebrandt S, Lammert F, Eitner F, Floege J, Ostendorf T.

J Am Soc Nephrol. 2007 May;18(5):1508-15. Epub 2007 Mar 27.

16.

Regulator of G protein signaling 2 (RGS2) deficiency accelerates the progression of kidney fibrosis.

Jang HS, Kim JI, Noh M, Rhee MH, Park KM.

Biochim Biophys Acta. 2014 Sep;1842(9):1733-41. doi: 10.1016/j.bbadis.2014.06.022. Epub 2014 Jun 26.

17.

Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction.

Eis V, Luckow B, Vielhauer V, Siveke JT, Linde Y, Segerer S, Perez De Lema G, Cohen CD, Kretzler M, Mack M, Horuk R, Murphy PM, Gao JL, Hudkins KL, Alpers CE, Gröne HJ, Schlöndorff D, Anders HJ.

J Am Soc Nephrol. 2004 Feb;15(2):337-47.

18.

Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction.

Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K.

Am J Pathol. 2011 Feb;178(2):572-9. doi: 10.1016/j.ajpath.2010.10.009.

19.

Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity.

Ma LJ, Corsa BA, Zhou J, Yang H, Li H, Tang YW, Babaev VR, Major AS, Linton MF, Fazio S, Hunley TE, Kon V, Fogo AB.

Am J Physiol Renal Physiol. 2011 May;300(5):F1203-13. doi: 10.1152/ajprenal.00468.2010. Epub 2011 Mar 2.

20.

Renal interstitial fibrosis is reduced in angiotensin II type 1a receptor-deficient mice.

Satoh M, Kashihara N, Yamasaki Y, Maruyama K, Okamoto K, Maeshima Y, Sugiyama H, Sugaya T, Murakami K, Makino H.

J Am Soc Nephrol. 2001 Feb;12(2):317-25.

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