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Results: 1 to 20 of 105

1.

Extrasynaptic NMDA receptor involvement in central nervous system disorders.

Parsons MP, Raymond LA.

Neuron. 2014 Apr 16;82(2):279-93. doi: 10.1016/j.neuron.2014.03.030. Review.

PMID:
24742457
[PubMed - indexed for MEDLINE]
2.

Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.

Kaufman AM, Milnerwood AJ, Sepers MD, Coquinco A, She K, Wang L, Lee H, Craig AM, Cynader M, Raymond LA.

J Neurosci. 2012 Mar 21;32(12):3992-4003. doi: 10.1523/JNEUROSCI.4129-11.2012.

PMID:
22442066
[PubMed - indexed for MEDLINE]
Free Article
3.

Involvement of the GluN2A and GluN2B subunits in synaptic and extrasynaptic N-methyl-D-aspartate receptor function and neuronal excitotoxicity.

Zhou X, Ding Q, Chen Z, Yun H, Wang H.

J Biol Chem. 2013 Aug 16;288(33):24151-9. doi: 10.1074/jbc.M113.482000. Epub 2013 Jul 9.

PMID:
23839940
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects.

Vizi ES, Kisfali M, Lőrincz T.

Brain Res Bull. 2013 Apr;93:32-8. doi: 10.1016/j.brainresbull.2012.10.005. Epub 2012 Oct 23. Review.

PMID:
23089362
[PubMed - indexed for MEDLINE]
5.

Modulation of NMDA receptor at the synapse: promising therapeutic interventions in disorders of the nervous system.

Mellone M, Gardoni F.

Eur J Pharmacol. 2013 Nov 5;719(1-3):75-83. doi: 10.1016/j.ejphar.2013.04.054. Epub 2013 Jul 18. Review.

PMID:
23872417
[PubMed - indexed for MEDLINE]
6.

Developmental decrease in NMDA receptor desensitization associated with shift to synapse and interaction with postsynaptic density-95.

Li B, Otsu Y, Murphy TH, Raymond LA.

J Neurosci. 2003 Dec 3;23(35):11244-54.

PMID:
14657184
[PubMed - indexed for MEDLINE]
Free Article
7.

Functional roles of synaptic and extrasynaptic NMDA receptors in physiological and pathological neuronal activities.

Li ST, Ju JG.

Curr Drug Targets. 2012 Feb;13(2):207-21. Review.

PMID:
22204320
[PubMed - indexed for MEDLINE]
8.

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors.

Léveillé F, El Gaamouch F, Gouix E, Lecocq M, Lobner D, Nicole O, Buisson A.

FASEB J. 2008 Dec;22(12):4258-71. doi: 10.1096/fj.08-107268. Epub 2008 Aug 18.

PMID:
18711223
[PubMed - indexed for MEDLINE]
Free Article
9.

Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway.

Efthimiadi L, Farso M, Quirion R, Krantic S.

Neurodegener Dis. 2012;10(1-4):80-91. doi: 10.1159/000335911. Epub 2012 Feb 17.

PMID:
22354185
[PubMed - indexed for MEDLINE]
10.

Chronic blockade of extrasynaptic NMDA receptors ameliorates synaptic dysfunction and pro-death signaling in Huntington disease transgenic mice.

Dau A, Gladding CM, Sepers MD, Raymond LA.

Neurobiol Dis. 2014 Feb;62:533-42. doi: 10.1016/j.nbd.2013.11.013. Epub 2013 Nov 19.

PMID:
24269729
[PubMed - indexed for MEDLINE]
11.

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders.

Hardingham GE, Bading H.

Nat Rev Neurosci. 2010 Oct;11(10):682-96. doi: 10.1038/nrn2911. Epub 2010 Sep 15. Review.

PMID:
20842175
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dysregulation of synaptic and extrasynaptic N-methyl-D-aspartate receptors induced by amyloid-β.

Wang ZC, Zhao J, Li S.

Neurosci Bull. 2013 Dec;29(6):752-60. doi: 10.1007/s12264-013-1383-2. Epub 2013 Oct 17. Review.

PMID:
24136243
[PubMed - indexed for MEDLINE]
13.

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death.

Martel MA, Wyllie DJ, Hardingham GE.

Neuroscience. 2009 Jan 12;158(1):334-43. doi: 10.1016/j.neuroscience.2008.01.080. Epub 2008 Mar 4.

PMID:
18378405
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The chemical biology of clinically tolerated NMDA receptor antagonists.

Chen HS, Lipton SA.

J Neurochem. 2006 Jun;97(6):1611-26. Review.

PMID:
16805772
[PubMed - indexed for MEDLINE]
15.

NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors.

Zhou X, Hollern D, Liao J, Andrechek E, Wang H.

Cell Death Dis. 2013 Mar 28;4:e560. doi: 10.1038/cddis.2013.82.

PMID:
23538441
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated.

Hardingham GE, Bading H.

Biochim Biophys Acta. 2002 Nov 4;1600(1-2):148-53.

PMID:
12445470
[PubMed - indexed for MEDLINE]
17.

Extrasynaptic NMDA Receptor in Excitotoxicity: Function Revisited.

Zhou X, Chen Z, Yun W, Ren J, Li C, Wang H.

Neuroscientist. 2014 Aug 28. pii: 1073858414548724. [Epub ahead of print]

PMID:
25168337
[PubMed - as supplied by publisher]
18.

NMDA receptor function: subunit composition versus spatial distribution.

Köhr G.

Cell Tissue Res. 2006 Nov;326(2):439-46. Epub 2006 Jul 22. Review.

PMID:
16862427
[PubMed - indexed for MEDLINE]
19.

Calpain-mediated degradation of myocyte enhancer factor 2D contributes to excitotoxicity by activation of extrasynaptic N-methyl-D-aspartate receptors.

Wei G, Yin Y, Li W, Bito H, She H, Mao Z.

J Biol Chem. 2012 Feb 17;287(8):5797-805. doi: 10.1074/jbc.M111.260109. Epub 2012 Jan 3.

PMID:
22215669
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease.

Fan J, Gladding CM, Wang L, Zhang LY, Kaufman AM, Milnerwood AJ, Raymond LA.

Neurobiol Dis. 2012 Mar;45(3):999-1009. doi: 10.1016/j.nbd.2011.12.019. Epub 2011 Dec 14.

PMID:
22198502
[PubMed - indexed for MEDLINE]

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