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Items: 1 to 20 of 309

1.

Fuzheng Qingjie recipe induces apoptosis in HepG2 cells via P38 MAPK activation and the mitochondria-dependent apoptotic pathway.

Chen XZ, Li JN, Zhang YQ, Cao ZY, Liu ZZ, Wang SQ, Liao LM, Du J.

Mol Med Rep. 2014 Jun;9(6):2381-7. doi: 10.3892/mmr.2014.2138. Epub 2014 Apr 11.

PMID:
24737008
2.

Gambogenic acid induced mitochondrial-dependent apoptosis and referred to phospho-Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells.

Yan F, Wang M, Li J, Cheng H, Su J, Wang X, Wu H, Xia L, Li X, Chang HC, Li Q.

Environ Toxicol Pharmacol. 2012 Mar;33(2):181-90. doi: 10.1016/j.etap.2011.12.006. Epub 2011 Dec 10.

PMID:
22222560
3.

Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis.

Zhao J, Chen X, Lin W, Wu G, Zhuang Q, Zhong X, Hong Z, Peng J.

Int J Oncol. 2013 Mar;42(3):971-8. doi: 10.3892/ijo.2013.1779. Epub 2013 Jan 18.

PMID:
23338043
4.

Jiedu Xiaozheng Yin decoction inhibits hepatoma cell proliferation by inducing apoptosis via the mitochondrial-mediated pathway.

Cao Z, Chen X, Lin W, Zhao J, Zheng L, Ye H, Liao L, Du J.

Mol Med Rep. 2015 Aug;12(2):2800-6. doi: 10.3892/mmr.2015.3696. Epub 2015 Apr 28.

PMID:
25936398
5.

13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.

Su CC, Chen JY, Din ZH, Su JH, Yang ZY, Chen YJ, Wang RY, Wu YJ.

Mar Drugs. 2014 Oct 23;12(10):5295-315. doi: 10.3390/md12105295.

7.

Duhuo Jisheng decoction treatment inhibits the sodium nitroprussiate‑induced apoptosis of chondrocytes through the mitochondrial‑dependent signaling pathway.

Liu F, Liu G, Liang W, Ye H, Weng X, Lin P, Li H, Chen J, Liu X, Li X.

Int J Mol Med. 2014 Dec;34(6):1573-80. doi: 10.3892/ijmm.2014.1962. Epub 2014 Oct 10.

PMID:
25339266
8.

The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells.

Zhou QM, Wang S, Zhang H, Lu YY, Wang XF, Motoo Y, Su SB.

Acta Pharmacol Sin. 2009 Dec;30(12):1648-58. doi: 10.1038/aps.2009.166.

9.

Triggering of p38 MAPK and JNK signaling is important for oleanolic acid-induced apoptosis via the mitochondrial death pathway in hypertrophic scar fibroblasts.

Chen JY, Zhang L, Zhang H, Su L, Qin LP.

Phytother Res. 2014 Oct;28(10):1468-78. doi: 10.1002/ptr.5150. Epub 2014 Apr 6.

PMID:
24706573
10.

Fuzheng Qingjie Granules Inhibit Growth of Hepatoma Cells via Inducing Mitochondria-Mediated Apoptosis and Enhancing Immune Function.

Chen X, Cao Z, Zhang Y, Li J, Wang S, Du J, Liao L.

Integr Cancer Ther. 2016 Jun 22. pii: 1534735416654761. [Epub ahead of print]

PMID:
27335087
11.

TNFR1/TNF-α and mitochondria interrelated signaling pathway mediates quinocetone-induced apoptosis in HepG2 cells.

Zhang C, Wang C, Tang S, Sun Y, Zhao D, Zhang S, Deng S, Zhou Y, Xiao X.

Food Chem Toxicol. 2013 Dec;62:825-38. doi: 10.1016/j.fct.2013.10.022. Epub 2013 Oct 22.

PMID:
24161692
12.
13.

Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.

Chiang JH, Yang JS, Ma CY, Yang MD, Huang HY, Hsia TC, Kuo HM, Wu PP, Lee TH, Chung JG.

Chem Res Toxicol. 2011 Jan 14;24(1):20-9. doi: 10.1021/tx100248s. Epub 2010 Dec 2.

PMID:
21126053
14.

The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.

Kang YH, Lee SJ.

J Cell Physiol. 2008 Oct;217(1):23-33. doi: 10.1002/jcp.21470.

PMID:
18412143
15.

A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.

Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):659-71. doi: 10.1016/j.taap.2013.10.015. Epub 2013 Oct 22.

PMID:
24161344
16.

BBR induces apoptosis in HepG2 cell through an Akt-ASK1-ROS-p38MAPKs-linked cascade.

Hyun MS, Hur JM, Mun YJ, Kim D, Woo WH.

J Cell Biochem. 2010 Feb 1;109(2):329-38. doi: 10.1002/jcb.22384.

PMID:
19950206
17.

Induction of apoptosis by fucoidan in human leukemia U937 cells through activation of p38 MAPK and modulation of Bcl-2 family.

Park HS, Hwang HJ, Kim GY, Cha HJ, Kim WJ, Kim ND, Yoo YH, Choi YH.

Mar Drugs. 2013 Jul 4;11(7):2347-64. doi: 10.3390/md11072347.

18.

Bear bile powder (熊胆粉) induces apoptosis of human hepatocellular carcinoma cells via mitochondrion-dependent pathway.

Zhao JY, Chen ZH, Lin W, Zhong XY, Chen XZ, Peng J, Hong ZF.

Chin J Integr Med. 2014 Feb;20(2):123-9. doi: 10.1007/s11655-013-1581-9. Epub 2014 Mar 6.

PMID:
24619237
19.
20.

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

Park MT, Choi JA, Kim MJ, Um HD, Bae S, Kang CM, Cho CK, Kang S, Chung HY, Lee YS, Lee SJ.

J Biol Chem. 2003 Dec 12;278(50):50624-34. Epub 2003 Sep 30.

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